Author(s):
Santosh Karajgi, Sushma Angadi, Shripad Potadar, C.C. Patil
Email(s):
santosh.karajgi@gmail.com
DOI:
10.52711/0974-360X.2023.00556
Address:
Santosh Karajgi*, Sushma Angadi, Shripad Potadar, C.C. Patil
Department of Pharmaceutical Quality Assurance, BLDEA’s SSM College of Pharmacy and Research Centre, BLDE University Campus, Vijayapur 586103, Karnataka, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 7,
Year - 2023
ABSTRACT:
For the simultaneous estimation of Vortioxetine Hydrochloride pharmaceuticals, a simple, accurate, precise, and reproducible method has been developed. For Quantitative Analysis of First Order Derivative, no UV methodologies have been described, it was felt that a novel approach to drug analysis using methanol as a solvent was required. Vortioxetine hydrochloride has absorbance maximum at 230 nm. This drug obeys Beer's law in concentration range of 10-50µg/ml. The recovery studies confirmed the proposed method's accuracy, and the results were validated in accordance with ICH guidelines. The outcomes were found to be satisfactory and reproducible. Thus the proposed method can be successfully applied for the quantitative analysis of Vortioxetine hydrochloride.
Cite this article:
Santosh Karajgi, Sushma Angadi, Shripad Potadar, C.C. Patil. Vortioxetine Estimation in its Drug Formulations by fist order derivative UV Spectrophotometric Method. Research Journal of Pharmacy and Technology 2023; 16(7):3363-6. doi: 10.52711/0974-360X.2023.00556
Cite(Electronic):
Santosh Karajgi, Sushma Angadi, Shripad Potadar, C.C. Patil. Vortioxetine Estimation in its Drug Formulations by fist order derivative UV Spectrophotometric Method. Research Journal of Pharmacy and Technology 2023; 16(7):3363-6. doi: 10.52711/0974-360X.2023.00556 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-7-53
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