Author(s):
Latifa Nasser A. Abdulqawi, Syed Atheruddin Quadri, Sehbanul Islam, Manas Kumar Santra
Email(s):
latifaabdulqawi@gmail.com , dratheruddin.qs@gmail.com , sehbanalig@gmail.com , manas@nccs.res.in
DOI:
10.52711/0974-360X.2023.00506 
Address:
Latifa Nasser A. Abdulqawi1*, Syed Atheruddin Quadri2, Sehbanul Islam3,4, Manas Kumar Santra3
1Department of Zoology, Maulana Azad Collage, Dr Babasaheb Ambedkar Marathwada University, Aurangabad - 431004, Maharashtra, India.
2Department of Zoology, Maulana Azad Collage, Dr. Rafiq Zakaria Campus, Aurangabad - 431001, Maharashtra, India.
3National Centre for Cell Science, NCCS Complex, Ganeshkhind Road, Pune - 411007, Maharashtra, India.
4Department of Biotechnology, Savitribai Phule Pune University, Ganeshkhind Road, Pune - 411007, Maharashtra India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 7,
Year - 2023
ABSTRACT:
Tribulus terrestris and Withania somnifera have been used in Indian medicine for a long time to treat a variety of diseases. The Present study evaluates anticancer activities of methanolic and aqueous extracts of W. somnifera and T. terrestris against breast cancer cell lines (MCF-7) were tested using MTT assay In-vitro, concentrations ranging of extracts from 2.5µg/ml to 25µg/ml.The results showed that all the plant extracts inhibited breast cancer cells' growth in dose-dependent. Methanolic and aqueous extracts of W. somnifera showing higher anticancer activity whit IC50 14.20 and 17.00µg/ml, respectively. The results of this study give direction for more pharmacological evaluation of these plants and isolation of their active compounds that may be tested and developed into new drugs for the treatment of the cancer.
Cite this article:
Latifa Nasser A. Abdulqawi, Syed Atheruddin Quadri, Sehbanul Islam, Manas Kumar Santra. Evaluation of Anticancer Activity of Withania somnifera L. and Tribulus terrestris L. on Human Breast Cancer Cells In vitro. Research Journal of Pharmacy and Technology 2023; 16(7):3079-2. doi: 10.52711/0974-360X.2023.00506
Cite(Electronic):
Latifa Nasser A. Abdulqawi, Syed Atheruddin Quadri, Sehbanul Islam, Manas Kumar Santra. Evaluation of Anticancer Activity of Withania somnifera L. and Tribulus terrestris L. on Human Breast Cancer Cells In vitro. Research Journal of Pharmacy and Technology 2023; 16(7):3079-2. doi: 10.52711/0974-360X.2023.00506 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-7-3
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