Author(s): Indumathi. K. P, S. Sibyl

Email(s): indumatp@srmist.edu.in , indhuparthiban@yahoo.co.in

DOI: 10.52711/0974-360X.2023.00412   

Address: Indumathi. K. P1*, S. Sibyl2
1Senior Lecturer, Department of Public Health Dentistry, SRM Institute of Science and Technology, SRM Kattankulathur Dental College and Hospital, Kattankulathur - 603203, Chengalpattu District, Tamil Nadu, India.
2Reader, Department of Public Health Dentistry, SRM Institute of Science and Technology, SRM Kattankulathur Dental College and Hospital, Kattankulathur - 603203, Chengalpattu District, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 5,     Year - 2023


ABSTRACT:
Vitamin D is a steroid hormone that has long been recognized for its function in calcium and phosphorus regulation and bone mineralization. As dentists, we are well aware of the role it plays in tooth growth and mineralization. Vitamin D, in addition to supporting calcium homeostasis, appears to control a variety of physiologic processes. Vitamin D deficiency though appears as a single element deficiency its impact on the entire human body is tremendous. It is a growing health issue but still awareness and the importance of maintaining adequate levels in the body is not known by most of the population. Vitamin D deficiency affects individuals of all ages, including those born to aged adults. In this article, we will be focusing on the function physiological action, and pharmacology of vitamin D. We will also review how vitamin D insufficiency affects dental caries, child oral health, periodontium, orthodontic tooth movement, and oral cancer.


Cite this article:
Indumathi. K. P, S. Sibyl. Vitamin D and its Influence on Oral Health: A Literature Review. Research Journal of Pharmacy and Technology 2023; 16(5):2507-2. doi: 10.52711/0974-360X.2023.00412

Cite(Electronic):
Indumathi. K. P, S. Sibyl. Vitamin D and its Influence on Oral Health: A Literature Review. Research Journal of Pharmacy and Technology 2023; 16(5):2507-2. doi: 10.52711/0974-360X.2023.00412   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-5-71


REFERENCES:
1.    Botelho et al. Vitamin D Deficiency and Oral Health: A Comprehensive Review. Nutrients. 2020; 12(5): 1471. doi:10.3390/nu12051471
2.    Millen, A. E., & Pavlesen, S.  Could Vitamin D Influence Risk for Periodontal Disease—to “D” or Not to “D”? Current Oral Health Reports. 2020;7(1):98–111. doi:10.1007/s40496-020-00253-7
3.    Rawal G et al. Health and the vitamin D. Int J Health Sci Res.2015;5(5):416-423. https://www.ijhsr.org/IJHSR_Vol.5_Issue.5_May2015/58.pdf
4.    Stein SH, Tipton DA. Vitamin D and its impact on oral health-an update. J Tenn Dent Assoc. 2011;91(2):30-33. https://pubmed.ncbi.nlm.nih.gov/21748977/
5.    Khammissa, R. A. G. et al. Vitamin D Deficiency as It Relates to Oral Immunity and Chronic Periodontitis. International Journal of Dentistry. 2018;1: 1–9. doi:10.1155/2018/7315797
6.    Dragonas, P. et al. Association of vitamin D with periodontal disease: a narrative review. Oral Health Prev Dent. 2020;18(2):103-114. doi: 10.3290/j.ohpd.a44323.
7.    Nalbantoglu, B., & Nalbantoglu, A. Vitamin D Levels in Children with Recurrent Aphthous Stomatitis. Ear, Nose & Throat Journal. 2019; 99(7): 460–463. doi:10.1177/0145561319882783
8.    .Chapple, I. L. et al.  Interaction of lifestyle, behaviour or systemic diseases with dental caries and periodontal diseases: consensus report of group 2 of the joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. Journal of Clinical Periodontology. 2017; 44: S39–S51. doi:10.1111/jcpe.12685
9.    Schroth, R. J. et al. Vitamin D status of children with severe early childhood caries: a case–control study. BMC Pediatrics. 2013; 13(1):174. doi:10.1186/1471-2431-13-174
10.    Lhamo, Y. et al. Epidemic of Vitamin D Deficiency and Its Management: Awareness among Indian Medical Undergraduates. Journal of Environmental and Public Health. 2017; 1–7. doi:10.1155/2017/2517207
11.    Gallieni, M. et al. Vitamin D: Physiology and Pathophysiology. The International Journal of Artificial Organs. 2009; 32(2): 87–94. doi:10.1177/039139880903200205
12.    Basit, S. Vitamin D in health and disease: a literature review. British Journal of Biomedical Science. 2013; 70(4), 161–172. doi:10.1080/09674845.2013.11669951
13.    Martelli, F. (2014). Vitamin D: relevance in dental practice. Clinical Cases in Mineral and Bone Metabolism. doi:10.11138/ccmbm/2014.11.1.015
14.    Girgis E, Reyad AA. Vitamin D: Pharmacology and Clinical Challenges in Oral Health Care. J Int Acad Periodontol. 2019;21(3):118-124. https://pubmed.ncbi.nlm.nih.gov/31473704/
15.    Laird, E. et al. Vitamin D and Bone Health; Potential Mechanisms. Nutrients. 2010;2(7): 693–724. doi:10.3390/nu2070693
16.    Weitzmann, M. N.  Estrogen deficiency and bone loss: an inflammatory tale. Journal of Clinical Investigation. 2006;116(5):1186–1194. doi:10.1172/jci28550
17.    Slemenda, C. W. (1990). Predictors of Bone Mass in Perimenopausal Women. Annals of Internal Medicine. 1990; 112(2):96-101. doi:10.7326/0003-4819-112-2-96
18.    Lips, P. Vitamin D Deficiency and Secondary Hyperparathyroidism in the Elderly: Consequences for Bone Loss and Fractures and Therapeutic Implications. Endocrine Reviews. 2001; 22(4): 477–501. doi:10.1210/edrv.22.4.0437
19.    World Health Organisation. Technical Report Series 843. World Health Organisation; Geneva, Switzerland: 1994. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. (n.d.).
20.    Marshall, D. et al. Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ. 1996; 312(7041):1254–1259. doi:10.1136/bmj.312.7041.1254
21.    Haentjens, P. et al. The Economic Cost of Hip Fractures Among Elderly Women. The Journal of Bone and Joint Surgery-American Volume. 2001; 83(4): 493–500. doi:10.2106/00004623-200104000-00003
22.    Bergwitz, C., & Juppner, H. Regulation of Phosphate Homeostasis by PTH, Vitamin D, and FGF23. Annual Review of Medicine. 2010; 61(1):91–104. doi: 10.1146/annurev.med.051308.111339
23.    Hujoel, P. P.  Vitamin D and dental caries in controlled clinical trials: systematic review and meta-analysis. Nutrition Reviews.2012;71(2): 88–97. doi:10.1111/j.1753-4887.2012. 00544.x
24.    Patil, D. J. Clinical Implications of Vitamin D in Oral Diseases- A Review. Journal of Pharmaceutical Research International. 2021; 9(11):103–110. doi:10.9734/jpri/2021/v33i30a31621
25.    Tanaka, K. et al. Higher vitamin D intake during pregnancy is associated with reduced risk of dental caries in young Japanese children. Annals of Epidemiology. 2015;2 5(8):620–625. doi: 10.1016/j.annepidem.2015.03.020
26.    Swapna, L. A., & Abdulsalam, R. Vitamin D Deficiency and its Effects on Tooth Structure and pulpal changes. Open Access Macedonian Journal of Medical Sciences. 2021;9(F): 81–87. doi:10.3889/oamjms.2021.5651
27.    Silva, C. C. et al. Prenatal or childhood serum levels of vitamin D and dental caries in paediatric patients: A systematic review. Oral Health Prev Dent. 2020; 18: 653-668. doi: 10.3290/j.ohpd.a45089.
28.    Jagelaviciene, E. et al. The Relationship between Vitamin D and Periodontal Pathology. Medicine. 2018;54(3): 45. doi:10.3390/medicina54030045
29.    Almoammar, K. Vitamin D and orthodontics: an insight review. Clinical, Cosmetic and Investigational Dentistry. 2018; Volume 10: 165–170. doi:10.2147/ccide.s157840
30.    Anderson, P. H. Vitamin D Activity and Metabolism in Bone. Current Osteoporosis Reports. 2017; 15(5): 443–449. doi:10.1007/s11914-017-0394-8
31.    Krall, E. A. et al. Calcium and vitamin D supplements reduce tooth loss in the elderly. The American Journal of Medicine. 2001;111(6):452–456. doi:10.1016/s0002-9343(01)00899-3
32.    Udeabor, S. E. et al. Serum levels of 25‐hydroxy‐vitamin D in patients with oral squamous cell carcinoma: Making a case for chemoprevention. Clinical and Experimental Dental Research. 2020;6(4), 428–432. doi:10.1002/cre2.294
33.    Grimm, M. et al. Serum vitamin D levels of patients with oral squamous cell carcinoma (OSCC) and expression of vitamin D receptor in oral precancerous lesions and OSCC. Medicina Oral Patología Oral y Cirugia Bucal. 2015; 20(2):188–195. doi:10.4317/medoral.20368
34.    Fathi, N. et al. Role of vitamin D and vitamin D receptor (VDR) in oral cancer. Biomedicine & Pharmacotherapy. 2019; 109: 391–401. doi:10.1016/j.biopha.2018.10.102

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