Author(s):
Jayakumari L, Sivaraj C, Manimaran A
Email(s):
mailtomanimaaran@gmail
DOI:
10.52711/0974-360X.2023.00354
Address:
Jayakumari L1, Sivaraj C2, Manimaran A1
1Department of Advanced Zoology and Biotechnology, Government Arts College (Autonomous) Nandanam, Chennai – 600 035,Tamilnadu, India.
2ARMATS Biotek Training and Research Institute Guindy, Chennai - 600032, Tamilnadu, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 5,
Year - 2023
ABSTRACT:
Syzygium samarangense is a potential medicinal plant and is effective for various health issues such as improving digestion, protecting against diabetes, lowering cholesterol to prevent certain types of cancers. The objectives of the study is to evaluate the antioxidant and antibacterial activities of methanol leaves extract of Syzygium samarangense (pink wax apple) and to identify volatile and semi-volatile compounds by GC-MS analysis. Antioxidant testing methods such as radical scavenging assays and reducing power assays were carried out for methanol leaves extract of Syzygium samarangense.
Cite this article:
Jayakumari L, Sivaraj C, Manimaran A. Methanol leaf extract of Syzygium samarangense: Antioxidant, Antibacterial Activities and GC-MS analysis. Research Journal of Pharmacy and Technology 2023; 16(5):2154-0. doi: 10.52711/0974-360X.2023.00354
Cite(Electronic):
Jayakumari L, Sivaraj C, Manimaran A. Methanol leaf extract of Syzygium samarangense: Antioxidant, Antibacterial Activities and GC-MS analysis. Research Journal of Pharmacy and Technology 2023; 16(5):2154-0. doi: 10.52711/0974-360X.2023.00354 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-5-13
REFERENCES:
1. Behera S, Babu SM, Ramani YR, Choudhury PK. A Comparative Study on Phytochemical Investigation and Antioxidant Activity of Poly herbal Mixture of Ocimum canum and Pongamia pinnata hydro-alcoholic Leaf Extracts. Research J. Pharmacognosy and Phytochemistry. 2012 Sep-Oct; 4(5): 250-261. https://rjpponline.org/ShowPDF_Paper.aspx.
2. Budiono, Elfita, Muhami, Yohandini H, Widjajanti H, Antioxitant Activity of Syzygium samarangense L. and their Endophytic fungi. Molekul. 2019 Jun; 14(1): 48-55. DOI: http://dx.doi.org/10.20884/1.jm.2019.14.1.503.
3. Insani AY, Prameahwari MC, Muharrom NA, Hidayati T, Nugrahani AP, Sakinah EN. Syzygium samarangense leaves ointment Enhances Wound Healing Process Of Skin Burn Based On Collagen. Journal of Agromedicine and Medical Sciences. 2017 Dec; 3(3): 30-33. DOI:10.19184/ams.v3i3.6160.
4. Nair A G, S Krishna, C Ravikrishna, P Madhusudanan., New and rare flavonol glycosides from leaves of Syzygium samarangense. Elsevier, Fitoterapia. 1999; 70: 148-151. https://doi.org/10.1016/S0367-326X(99)00013-1.
5. Choironi NA, Fareza MS. Phytochemical Screening and Antibacterial Activity of Ethanolic Extract of Syzygium samarangense Leaves. Journal of Kartika Kimia. 2018 Nov, 1 (1): 1-4. https://doi.org/10.26874/jkk.v1i1.2.
6. Tarign C, Pramastya H, Insanu M, Fidrianny I. Syzygium samarangense: Review of phytochemical Compounds and pharmacological Activities. Biointerface Research in Applied Chemistry. 2021; 12(2): 2084-2107. https://doi.org/10.33263/BRIAC122.20842107.
7. Purushotham KG, Arun P, Johnsy Jayarani J, Vasanthakumari R, Chamundeeswari D. In Vitro Antibacterial and Antifungal Assay of Tectona grandis-A Screening Study. Research J. Pharmacognosy and Phytochemistry. 2010 Jan-Feb; 2(1): 57-60. https://rjpponline.org/ShowPDF_Paper.aspx.
8. Aung EE, Kristanti AN, Aminah NS, Takaya Y, Ramadhan R. Plant description, phytochemical constituents and bioactivities of syzygium samarangense genus: A review. Journal open Chemistry. 2020 Oct 13; 18: 1256–1281. https://doi.org/10.1515/chem-2020-0175.
9. Yang J, Su JC, Pinglei X, Huang XJ, Zhang DM, Ye WC, Wang Y. Acylphloroglucinol derivatives from the leaves of Syzygium samarangense and their cytotoxic activities. Elsevier 2018 Jun; 129: 1-6. https://doi.org/10.1016/j.fitote.2018.06.002.
10. Mollika S, Islam N, Parvin N, Kabir A, Sayem MW, Luthfunnesa, Saha R. Evaluation of Analgesic, Anti-inflammatory and CNS Activities of the Methanolic Extract of Syzygium samarangense Leave. Global Journal of Pharmacology. 2014; 8(1): 39-46. DOI: 10.5829/idosi.gjp.2014.8.1.81223.
11. Madhavi M, Raghu Ram M. Phytochemical screening and Eval;uation of Biological Activity of Root Extracts of Syzygium samarangense, International Journal of Research in Pharmacy and Chemistry. 2015; 5(4): 753-763. https://www.ijrpc.com/files/26-11-15/27-129.pdf.
12. Moneruzzaman Khandaker M, Jahan Sarwar Md, Nashriyah Mat, Boyce AN. Bioactive constituents, antioxitant and antimicrobial activities of three cultivars of wax apple (Syzygium samarangense L.) fruits. Research Journal of Biotechnology. 2015 Jan; 10 (1): 7-16. https://www.researchgate.net/publication/270703189.
13. Peter T, Padmavathi. D, Sajini. RJ, Sarala A. Syzygium samarangense a review on morphology, phytochemistry and pharmacological aspects . Asian Journal of Biochemical and Pharmaceutical Research. 2011; 1(4): 155-163. https://www.cabdirect.org/globalhealth/abstract/20123013209.
14. Tiny A, Johney J, Ragunahan R. Biogenic Synthesis of silver nanoparticles using Syzygium samarangense leaf extract and its Antioxidant, Antibacterial and Drug Conjugation studies. Journal of Pharmaceutical Sciences and Research. 2020 Aug; 12(8): 1124-1130. Available on https://www.jpsr.pharmainfo.in/Documents/Volumes/vol12issue08/jpsr12082020.pdf.
15. Liu X, Dong M, Chen X, Jiang M, Lv X, Yan G. Antioxidant activity and phenolics of endophytic Xylaria sp. From Ginkgo biloba. Elsiever, Food Chemistry. 2007 Apr; 105: 548-554. https://doi.org/10.1016/j.foodchem.2007.04.008.
16. Prieto P, Pineda M, Anguilar M. Spectrometric quantisation of antioxidant capacity through the formation of a Phosphomolybdenyum Complex: Specific application to the determination of Vitamin E. Analytical Biochemistry.1999; 269: 337-341. doi:10.1006/abio.1999.4019.
17. Yen GC, Chen H Y. Antioxidant activity of various tea extracts in relation to their antimutagenicity. Journal of Agricultural and Food Chemistry. 1995; 43(1): 27-32. https://doi.org/10.1021/jf00049a007.
18. Garg A, Mittal SK. Free radical scavenging, antioxidant activity And phenolic content of Salvadora oleoides Decne Leaves. Res. J. Pharmacognosy and Phytochem. 2018 Jan-Mar; 10(1): 27-35. DOI: 10.5958/0975-4385.2018.00005.5.
19. Manisha P, Verma Rohit K, Dharamveer, Koshy MK ,Saraf Shubhini A. Antioxidant Activity of Sida veronicaefolia. Research J. Pharmacognosy and Phytochemistry 2010; 2(1): 79-81. https://rjpponline.org/ShowPDF_Paper.aspx.
20. Nikhat F, Satynarayana D, Subhramanyam EVS. Isolation, Charectrisation and Screening of Antioxidant Activity of the Roots of Syzygiumcuminii (L) Skeel. Asian J. Research Chem. 2009 Apr-Jun; 2(2): 218-221. https://ajrconline.org/ShowPDF_Paper.aspx.
21. P. Arun, Purushotham KG, Jayarani J, Kumari V, Chamundeeswari D. Screening Antibacterial Activity of Various Extracts of Lawsonia inermis. Research J. Pharmacognosy and Phytochemistry. 2010 May-June; 2(3): 185-187. https://rjpponline.org/ShowPDF_Paper.aspx.
22. Paul S, Saha D. Comparative Study of the Efficacy of Barleria prionitis Leaf Extracts against Bacteria. Asian Journal of Pharmaceutical Research. 2012 Jul-Sep; 2(3): 107-110. https://asianjpr.com/Issues.aspx?VID=2&IID=3.
23. Barboza JN, Filho CSM, Silva RO, Jand Venes R. Medeiros, De Sousa DP. An Overview on the Anti-inflammatory Potential and Antioxidant Profile of Eugenol. Oxidative Medicine and Cellular Longevity. 2018; 9 pages, Article ID 3957262. https://doi.org/10.1155/2018/3957262.
24. Ashfaq MH, Siddique A, Shahid S. Antioxidant Activity of Cinnamon zeylanicum: (A Review). Asian Journal of Pharmaceutical Research. 2021 Apr-Jun; 11(2):106-116. DOI: 10.52711/2231-5691.2021.00021.
25. Saravanakumar K, Chelliah R, Ramakrishnan SR, Kathresan K, Oh DH, Wang MH. Antibacterial and antioxidant potentials of non-cytotoxic extract of trichoderma atroviride. Elsevier, Microbial Pathogenesis. 2018 Feb; 115: 338-342. https://doi.org/10.1016/j.micpath.2017.12.081.
26. Balkrushna GS, Mohan GK, Ravindra CS. Spectroscopic Characterization of Phytol isolated from Thespesia populnea Leaves. Res. J. Pharmacognosy and Phytochem. 2018 Jul-Sep; 10(3):203-206. DOI: 10.5958/0975-4385.2018.00032.8.
27. Sharma V, Chitranshi N, Agarwal AK. Significance and Biological Importance of Pyrimidine in the Microbial World. Indian International of Medicinal Chemistry. 2014 March; 1-31, Article ID 202784. https://doi.org/10.1155/2014/202784.
28. Divekar K, Hardik J, Brahmani Priyadarshini S. Synthesis and Biological Evaluation of Some Novel Pyrimidine Derivatives. Asian J. Research Chem. 2011 Jan;4(1): 64-67. https://ajrconline.org/ShowPDF_Paper.aspx.