Author(s): Sugashini Settu, Sathiavelu Arunachalam

Email(s): asathiavelu@vit.ac.in

DOI: 10.52711/0974-360X.2023.00261   

Address: Sugashini Settu1, Sathiavelu Arunachalam2*
1School of Bioscience and Technology, Vellore Institute of Technology, Vellore - 14, Tamil Nadu, India.
2VIT School of Agricultural Innovations and Advanced Learning, Vellore Institute of Technology, Vellore - 14, Tamil Nadu, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2023


ABSTRACT:
In the past decade, much progress has been made in understanding the pathophysiology of inflammation and the implication of free radicals in it. Steroid drugs are usually used for treating inflammatory diseases but it requires prolonged treatment and also it causes serious issues. Therefore there is a need to search for alternate treatments. From this perspective, several medicinal plants have been proven to be efficient in treating inflammation and pain. At present, researchers are interested in examining pharmacological impacts and its mode of action of medicinal plants by in-vitro and in-vivo models. Therefore, in this study the methanol and petroleum ether leaf extracts of Momardica charantia, Citrullus lanatus, Coccinia grandis and Lagenaria siceraria were studied for anti-inflammatory activity using protein denaturation assay.


Cite this article:
Sugashini Settu, Sathiavelu Arunachalam. Evaluation of Anti-inflammatory activity of selected medicinal plants of Cucurbitaceae family. Research Journal of Pharmacy and Technology 2023; 16(4):1598-0. doi: 10.52711/0974-360X.2023.00261

Cite(Electronic):
Sugashini Settu, Sathiavelu Arunachalam. Evaluation of Anti-inflammatory activity of selected medicinal plants of Cucurbitaceae family. Research Journal of Pharmacy and Technology 2023; 16(4):1598-0. doi: 10.52711/0974-360X.2023.00261   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-4-9


REFERENCE
1.    Abdullatif A. Ahmad N. Abed NA. Anti-inflammatory activity of natural products. Molecules 2016; 21: 1-19.doi:10.3390/molecules21101321
2.    Sunita V. Medicinal plants with anti-inflammatory activity. The journal of  Phytopharmacology 2016; 5: 157-159.doi:10.31254/phyto.2016.5407
3.    Oukacha A. Abderrahmane Z. Abdellah B. Saida T. Abdelhakim H. Anti-inflammatory activity of methanolic extract from Pistacia atiantica desf. leaves. Pharmacognosy Journal 2018; 10: 71-76.doi:10.5530/pj.2018.1.14
4.    Syed SAS. M.Ijaz H. M.Kashif A. Gildardo R. Natural products; Pharmacological importance of family Cucurbitaceae: A brief review. Mini-Reviews in Medicinal Chemistry 2014; 14: 1-11.doi:10.2174/13895575140820113055
5.    Kamau JK. Nithiga PM. Mwonjoria JK. Ngeranwa JJN. Ngugi MP. Anti-inflammatory activity of methanolic leaf extract of Kigelia Africana(Lam.) benth and stem bark extract of Acacia kockii de wild in mice. Journal of  Developing Drugs 2016; 5: 2-8. doi:10.4172/2329-6631.1000156
6.    Jing Z. Yue G. Tom V. Steve C. Thomas B. Davis RM. Ah-Ng Tony K. James ES. Qingli W. Phytochemical analysis and anti-inflammatory activity of the extracts of the African medicinal plant Ximenia caffra. Journal of Analytical Methods in Chemistry 2015: 1-9.doi.org/10.1155/2015/948262
7.    Angeline CHM. Krishnakumari S. Qualitative phytochemistry profile of watermelon (Citrullus vulgaris schrad) rind extracts with different solvents. Asian Journal of Pharmaceutical and Clinical Research 2015; 8: 62-65.
8.    Mercy A. Felicia N. A review on the economic uses of species of Cucurbitaceae and their sustainability in Nigeria. American Journal Plant Biology 2017; 2: 17-24.doi:10.11648/j.ajpb.20170201.14
9.    Thammaihraj SA. Vittal RR. An ethnobotanical investigation of Cucurbitaceae from south India: A review. Journal on Medicinal Plants Studies 2017; 5: 250-254.
10.    Ranjithadhevi VS. Gayathri S. Saranya S. Sugashini S. Lokesh R. Bioactivity of Phoenix dactylifera seed and its phytochemical analysis. International Journal of Green Pharmacy 2017; 11: 1-6. doi:10.22377/IJGP.V11I02.1037
11.    Gunathilake KDPP. Ranaweera KKDS. Vasantha Rupasinghe HP. In Vitro anti-inflammatory properties of selected green leafy vegetables. Biomedicines 2018; 6: 1-10. doi:10.3390/biomedicines6040107
12.    Ratnasooriya WD. Deraniyagala S. Galhena G. Liyanage SSP. Bathige SDNK. Jayakody JRAC. Anti-inflammatory activity of the aqueous leaf extract of Ixora coccinea. Pharmaceutical Biology 2005; 43: 147-152.doi.org/10.1080/13880200590919483
13.    Pekamwar SS. Kalyankar TM. Kotate SS. Pharmacological activities of Coccinia grandis: Review. Journal of Applied Pharmaceutical Science 2013; 3;114-115.doi:10.7324/JAPS.2013.3522

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available