Author(s): Arwa R. Althaher

Email(s): ,

DOI: 10.52711/0974-360X.2023.00300   

Address: Arwa R. Althaher*
Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman 11733, Jordan.
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2023

Ajuga orientalis L. is a member of the Lamiaceae family. Many biological properties of A. orientalis, such as antibacterial, anticancer, antioxidant, and anti-inflammatory activities, have been documented. The current study aims to assess the in vitro antidiabetic efficacy of aerial parts A. orientalis extracts through digestive enzymes inhibition assay (?-amylase and ?-glucosidase), which are responsible for the digestion of poly and oligosaccharides. Acarbose, aqueous, and ethanolic extracts of A. orientalis were utilized in various concentrations (100, 200, 300, 400, and 500?g/ml). The absorbance values for the enzymes ?-amylase and ?-glucosidase at 540nm and 400nm, respectively, were measured using a spectrophotometer. Both extracts demonstrated significant inhibition of a-amylase and a-glucosidase enzymes in a dose-dependent manner. Furthermore, the ethanolic extract showed more inhibitory activity than the aqueous extract. In conclusion, A. orientalis extracts exhibited in vitro antidiabetic activity.

Cite this article:
Arwa R. Althaher. In vitro Assessment of the Antidiabetic Activity of Aqueous and Ethanolic Extracts from the Aerial Parts of Ajuga orientalis L.. Research Journal of Pharmacy and Technology 2023; 16(4):1828-2. doi: 10.52711/0974-360X.2023.00300

Arwa R. Althaher. In vitro Assessment of the Antidiabetic Activity of Aqueous and Ethanolic Extracts from the Aerial Parts of Ajuga orientalis L.. Research Journal of Pharmacy and Technology 2023; 16(4):1828-2. doi: 10.52711/0974-360X.2023.00300   Available on:

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