Author(s): Abdulhusein Mizhir Almaamuri, Ghassan Salah Ahmed, Falah Hassan Shari, Aiman Mohammed Baqir Al-Dhalimy, Haider Abdulkareem Almashhadani, Mustafa M. Kadhim

Email(s): ,

DOI: 10.52711/0974-360X.2023.00256   

Address: Abdulhusein Mizhir Almaamuri1, Ghassan Salah Ahmed2, Falah Hassan Shari3, Aiman Mohammed Baqir Al-Dhalimy4,5, Haider Abdulkareem Almashhadani6, Mustafa M. Kadhim7,8
1Pharmacy Department, Al-Mustaqbal University College, Baghdad, Iraq.
2Department of Clinical Pharmacy, College of Pharmacy, University of Basrah, Iraq.
3Department of Clinical Laboratory Sciences, College of Pharmacy, University of Basrah, Iraq.
4Department of Nursing, Altoosi University College, Najaf, Iraq.
5The Islamic University, Najaf, Iraq.
6Dentistry Department, Al-Rasheed University College, Iraq.
7Research Center, Kut University College, Kut, Wasit 52001, Iraq.
8Medical Laboratory Techniques Department, Al-Farahidi University, Iraq, Baghdad.
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2023

The extract of fig fruit has shown significant medical usefulness in various fields. The entrance of nanotechnology into the field of medicinal and pharmacology has shown remarkable advantages. Plants contain diverse molecules thatcan reduce metals, and provide a safe, eco-friendly approach for synthesizing nanoparticles. Iron oxide nanoparticles (IONPs) have been reported to possess an antimicrobial effect against some strains of bacteria and moulds. We have aimed to synthesize IONPs from fig fruit extract and investigate the influence of fig extract and IONPs in wound healing of mice. UV-Vis spectroscopy, X-ray diffraction (XRD), and field emission scanning electron microscopy were used to characterize the IONPs that were produced. The UV-Vis spectrum has indicated a maximum absorbance of around 400 nm, which is characterized by IONPs. The XRD examination has indicated the formation of a-Fe2O3 NPs, while the morphological examination by FESEM indicated the presence of aggregated rough IONPs. Then, 15 mice were divided into three groups equally; control, fig extract treated, and IONPs treated mice. Mice treated with fig extract or IONPs have shown obvious improvement after 5 days compared to control. On the 14th day, almost complete healing was observed in mice treated with fig fruit extract or IONPs. In conclusion, the possibility of using plants and NPs as antibacterial and anti-inflammatory agents would provide a great advancement in the administration of mild skin injuries.

Cite this article:
Abdulhusein Mizhir Almaamuri, Ghassan Salah Ahmed, Falah Hassan Shari, Aiman Mohammed Baqir Al-Dhalimy, Haider Abdulkareem Almashhadani, Mustafa M. Kadhim. The Wound Healing effect of the Green Synthesized Iron Oxide Nanoparticles: A Study on Mice. Research Journal of Pharmacy and Technology 2023; 16(4):1569-3. doi: 10.52711/0974-360X.2023.00256

Abdulhusein Mizhir Almaamuri, Ghassan Salah Ahmed, Falah Hassan Shari, Aiman Mohammed Baqir Al-Dhalimy, Haider Abdulkareem Almashhadani, Mustafa M. Kadhim. The Wound Healing effect of the Green Synthesized Iron Oxide Nanoparticles: A Study on Mice. Research Journal of Pharmacy and Technology 2023; 16(4):1569-3. doi: 10.52711/0974-360X.2023.00256   Available on:

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