Author(s): Pratiwi Soesilawati, Nur Imamatul Ummah, Sesaria Junita Mega Rahma Syahnia, Niken Luthfiyya Arini, Aqsa Sjuhada Oki

Email(s): pratiwi-s@fkg.unair.ac.id

DOI: 10.52711/0974-360X.2023.00289   

Address: Pratiwi Soesilawati2*, Nur Imamatul Ummah1, Sesaria Junita Mega Rahma Syahnia1, Niken Luthfiyya Arini1, Aqsa Sjuhada Oki2
1Undergraduate Student, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
2Department of Oral Biology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2023


ABSTRACT:
Periodontitis is a destructive inflammatory disease caused by a specific microorganism causing progressive damage to areas, especially the alveolar bone and periodontal ligament. Clinical manifestations of periodontitis are tooth mobility, pocket formation, and loss of attachment. Periodontitis is divided into two groups, namely aggressive and chronic periodontitis. The prevalence of chronic periodontitis in the world is around 50%. Meanwhile, the prevalence of chronic periodontitis in Indonesia, according to Riskesdas 2018 is 67.8%. Porphyromonas gingivalis is a bacterium that causes chronic periodontitis, which can form biofilm plaque and cause damage to periodontal tissue resulting in tooth loss. The formation of biofilm plaques due to accumulation of opportunistic bacterial species accompanied by increased gram-negative bacterial. These changes in composition affect the host's immune response so that periodontitis develops into a chronic inflammatory condition. Therefore, we conducted a literature search to analyze the effect of oral biofilms on chronic periodontitis.


Cite this article:
Pratiwi Soesilawati, Nur Imamatul Ummah, Sesaria Junita Mega Rahma Syahnia, Niken Luthfiyya Arini, Aqsa Sjuhada Oki. The Role of Porphyromonas gingivalis in Oral Biofilm: Pathophysiology in Chronic Periodontitis. Research Journal of Pharmacy and Technology 2023; 16(4):1754-0. doi: 10.52711/0974-360X.2023.00289

Cite(Electronic):
Pratiwi Soesilawati, Nur Imamatul Ummah, Sesaria Junita Mega Rahma Syahnia, Niken Luthfiyya Arini, Aqsa Sjuhada Oki. The Role of Porphyromonas gingivalis in Oral Biofilm: Pathophysiology in Chronic Periodontitis. Research Journal of Pharmacy and Technology 2023; 16(4):1754-0. doi: 10.52711/0974-360X.2023.00289   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-4-37


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14.   Cervino G. Romeo U. Lauritano F. Bramanti E. Fiorillo L. D’Amico C. et al. Analysis of OSSTEM ® Dental Implant Structural Components: Evaluation of Different Direction Dynamic Loads. 2018;12219–229.doi.org/10.2174/1874210601812010219.

15.   Purbowati R. Hubungan Biofilm dengan Infeksi: Implikasi pada Kesehatan Masyarakat dan Strategi Mengontrolnya. 2018;5(1):1.doi.org/10.30742/jikw.v5i1.1.

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22.   Yan S. Wu G. Can Biofilm Be Reversed Through Quorum Sensing in Pseudomonas Aeruginosa? 2019;101582.doi.org/10.3389/fmicb.2019.01582.

23.   Abedon ST. Ecology of Anti-Biofilm Agents II: Bacteriophage Exploitation and Biocontrol of Biofilm Bacteria. 2015;8(3):559–589.doi.org/10.3390/ph8030559.

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