Author(s):
Ajith Venugopalan, Krupanidhi Karunanithi, Sreekrishnan TP, AnoojaThampi, Jinu Joy, Thara Thomas, Aswathy Ashok B, Roshini PR, Vimal Koshy, G. Sreekumar, Gireesh Kumar KP
Email(s):
ajith.v123@gmail.com
DOI:
10.52711/0974-360X.2023.00287 
Address:
Ajith Venugopalan1*, Krupanidhi Karunanithi2, Sreekrishnan TP3, AnoojaThampi4, Jinu Joy4, Thara Thomas4, Aswathy Ashok B4, Roshini PR4, Vimal Koshy1, G. Sreekumar1, Gireesh Kumar KP3
1Department of Emergency Medicine, MOSC Medical College Hospital, Kolenchery, Kerala, India.
2Swamy Vivekananda Medical College Hospital and Research Institute, Elayampalayam, Namakkal, Tamil Nadu, India.
3Department of Emergency Medicine and Critical Care, Amrita Institute of Medical Sciences, Amrita Vishwa Vidhyapeetham University, Kochi, Kerala, India.
4Department of Pharmacy Practice, Amrita School of Pharmacy, Amrita Vishwa Vidhyapeetham University, Kochi, Kerala, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 4,
Year - 2023
ABSTRACT:
Introduction: AIDS (acquired immune deficiency syndrome), caused by the human immune deficiency virus (HIV), is a chronic, potentially life-threatening condition. Non-communicable diseases require long – term care and treatment as they are chronic conditions that result in lifelong health consequences. In our study we tried to evaluate the prevalence of Non-Communicable Diseases (NCD) among HIV patients. Methodology: This is a prospective study consisting 191 patients who were presented to the Emergency Medicine and Critical Care Department over 2 year for various HIV related acute problems. Chi-square test was used to find significance of association of qualitative variables. Atherosclerotic cardiovascular disease scale (ASCVD) and Framingham risk score were used. Results: 65.45% of patients were in the age group 40-60 yrs. From the total number of HIV patients, 64.92% (123) of patients were affected by NCDs. The prevalence rate of dyslipidemia 49(25.7%) was found to be high, followed by hypertension 48(25.1%) and diabetes 36(18.8%). There is a major association (p value < 0.001) linking Framingham score and CAD and a borderline significance (p=0.093) between ASCVD score and CAD. Conclusion: The prevalence rate of non-communicable diseases among retro positive patients is high and should be screened in the same manner as done for routine patients. HIV patients presents to the Emergency room with disease related deteriorations and also with NCD associated complications. When managing in the emergency room it is always essential to think of these NCDs in HIV patients and the complication it can produce. This will help in early diagnosis, evaluate the complication in more organised manner and provide effective management. This will also provide in reducing the morbidity and mortality among such patients.
Cite this article:
Ajith Venugopalan, Krupanidhi Karunanithi, Sreekrishnan TP, AnoojaThampi, Jinu Joy, Thara Thomas, Aswathy Ashok B, Roshini PR, Vimal Koshy, G. Sreekumar, Gireesh Kumar KP. Prevalence of Non-Communicable Disease in HIV Infected patients coming to Emergency Medicine and Critical Care Department in A Tertiary Care Centre in South India. Research Journal of Pharmacy and Technology 2023; 16(4):1743-8. doi: 10.52711/0974-360X.2023.00287
Cite(Electronic):
Ajith Venugopalan, Krupanidhi Karunanithi, Sreekrishnan TP, AnoojaThampi, Jinu Joy, Thara Thomas, Aswathy Ashok B, Roshini PR, Vimal Koshy, G. Sreekumar, Gireesh Kumar KP. Prevalence of Non-Communicable Disease in HIV Infected patients coming to Emergency Medicine and Critical Care Department in A Tertiary Care Centre in South India. Research Journal of Pharmacy and Technology 2023; 16(4):1743-8. doi: 10.52711/0974-360X.2023.00287 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-4-35
REFERENCES:
1. Maheshwari P, Manju Sunny. A Prospective Study on the Knowledge, Attitude and Perception on HIV/AIDS among the Nursing and other Healthcare Professionals. Research J. Pharm. and Tech. 2016; 9(9):1403-1406. doi: 10.5958/0974-360X.2016.00271.
2. Thiruchelvi. R, Aryaman Das. Modus Operandi for Rehabilitating Aids with Tetrasilver Tetroxide Molecular Crystal Devices. Research J. Pharm. and Tech. 2019; 12(3): 1418-1424. doi: 10.5958/0974-360X.2019.00236.1
3. Jintanat Ananworanich, et al. HIV and Non-Communicable Diseases: The Asian Perspective. J Acquired Immune Deficiency Syndrome. 2014;67: S99-S103. PMID: 25117967. doi: 10.1097/QAI.0000000000000262
4. Nurul Diana Dzaraly, Nor Iza A. Rahman, Nordin Simbak, Suhaimi Ab. Wahab, Omar Osman, Salwani Ismail, Mainul Haque. Patterns of Communicable and Non-Communicable Diseases in Pilgrims during Hajj. Research J. Pharm. and Tech. 7(9): Sept. 2014 Page 1060-1064.
Available on: https://rjptonline.org/AbstractView.aspx?PID=2014-7-9-13
5. Raj Purnima, Temburnikar Pankaj, Agrawal Avantika, Shrivastava PK, Rathod Mritunjay and Verma VB. To Study Awareness of HIV/AIDS in Female HIV Positive Patient and Access Adverse Reactions in Female Patient on Anti Retro Viral Therapy along with Their Adherence to Therapy in Chhattisgarh. Research J. Pharmacology and Pharmacodynamics. 2011; 3(4): 171-175.
6. RT Kakade, SD Firke, PS Bafna, AK Tilva. Overview on Acquired immunodeficiency syndrome . Research J. Pharmacology and Pharmacodynamics. 4(3): 2012;158-162.
7. Sanat Sharma, Tabish Ahmed, Syed Sajid Ali, Raj Sharma, Devender Sachdev. Knowledge, Attitude and Practice about HIV amongst the Medical Undergraduates of Bastar Region. Research Journal of Pharmacology and Pharmacodynamics. 2014; 6(2): 82-85
8. College of Cardiology, American Heart Association. ASCVD Risk Estimator. 2014. Available on : https://tools.acc.org/ascvd-risk-estimator-plus/#!/calculate/estimate/
9. Estimation of cardiovascular risk in an individual patient without known cardiovascular disease Framingham risk score. 2015.
10. Gibson B Kagaruki, Mary T Mayige, Ester S Ngadaya et al. Magnitude and risk factor of non- communicable diseases among people living with HIV in Tanzania: a cross sectional study from Mbeya and Dares Salaam regions. BMC Public Health. 2014;14: 904-913. doi: https://doi.org/10.1186/1471-2458-14-904
11. Sylvie Lang, Murielle Mary Krause, Anne Simon, et al. HIV Replication and Immune Status are Independent Predictors of the risk of Myocardial Infarction in HIV infected individuals. CID. 2012;55(4):600-607. doi: 10.1093/cid/cis489
12. Reinsch N, et al. Are HIV patients Undertreated? Cardiovascular risk factors in HIV: results of the HIV-HEART study. Eur J Prev Cardiol. 2012 Apr;19:267-74. doi: 10.1177/1741826711398431.
13. Theo Smart. HIV and non-communicable diseases (NCDs). HATiP 2011 Issue 182: October;6:3. Available on: https://stoptb.org/wg/tb_hiv/assets/documents/HATIP_182_NCDs_HIV_&_TB.pdf
14. Ministry of Health GoK. Kenya NCD Estimates Report 2019. (NACC) NACC; 2019. Available on: https://www.health.go.ke/wp-content/uploads/2021/07/Kenya-Non-Communicable-Disease-NCD-Strategic-Plan-2021-2025.pdf
15. Virginia A. Triant, et al. Epidemiology of Coronary Heart Disease in HIV Patients. Rev Cardiovasc Med 2014;15: S1-S8.
16. Jintanat Ananworanich et al. HIV and Non Communicable Diseases: The Asian Perspective. J Acquir Immune Defic Syndr 2014;67: S99-S103 doi: 10.1097/QAI.0000000000000262.