Author(s): Deeksha Sharma, Abha Vashistha, Manish Sharma

Email(s): abhavashistha29@gmail.com

DOI: 10.52711/0974-360X.2023.00276   

Address: Deeksha Sharma1, Abha Vashistha2*, Manish Sharma3
1Department of Biotechnology and Microbiology, Meerut Institute of Engineering and Technology, NH-58, Baghpat Road, Bypass Crossing-250005, Meerut, U.P. (India).
2University Institute of Biotechnology, Chandigarh University, NH-95, Chandigarh-Ludhiana Highway -140413, Mohali, Punjab (India).
3Pioneer Center of Biosciencesfor Advanced Training and ResearchMohan Nagar- 201007, Ghaziabad, U.P. (India).
*Corresponding Author

Published In:   Volume - 16,      Issue - 4,     Year - 2023


ABSTRACT:
Inspite of multi model cure therapy the mortality rate among the patients of brain tumor always remain high.The low survival rate is due to the ability of these tumors to recur quickly and aggressively. The cellular, genetic, and epigenetic heterogeneity of Glioblastoma multiforme tumors makes designing targeted treatments difficult. Within the tumor there are distinct subpopulations of cells that are stem-like in their behavior and are critical as therapeutic target. The regulation of these cells at molecular level is not yet properly studied. The presence of hypoxic environment controls the stem cells and slower down the progression of tumor. The goal of this work is to use PCR to determine gene expression in glial cells that have been exposed to hypoxia.


Cite this article:
Deeksha Sharma, Abha Vashistha, Manish Sharma. Study of Gene Expression in Glioblastoma Hypoxic Model. Research Journal of Pharmacy and Technology 2023; 16(4):1685-8. doi: 10.52711/0974-360X.2023.00276

Cite(Electronic):
Deeksha Sharma, Abha Vashistha, Manish Sharma. Study of Gene Expression in Glioblastoma Hypoxic Model. Research Journal of Pharmacy and Technology 2023; 16(4):1685-8. doi: 10.52711/0974-360X.2023.00276   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-4-24


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