Author(s):
Rini Hamsidi, Myrna Adianti, Maya Septriana, Onny Priskila, Wahyuni, Adryan Fristiohady, Muhammad Hajrul Malaka, Vica Aspadiah, La Ode Muhammad Arlan, Karlies Sirupa Baka, Wiwied Ekasari, Aty Widyawaruyanti, Ahmad Fuad Hafid
Email(s):
rini.hamsidi@vokasi.unair.ac.id
DOI:
10.52711/0974-360X.2023.00136 
Address:
Rini Hamsidi1*, Myrna Adianti1, Maya Septriana1, Onny Priskila1, Wahyuni2, Adryan Fristiohady2, Muhammad Hajrul Malaka2, Vica Aspadiah2, La Ode Muhammad Arlan2, Karlies Sirupa Baka2, Wiwied Ekasari3, Aty Widyawaruyanti3,4, Ahmad Fuad Hafid3,4
1Department of Health, Faculty of Vocational Studies, Universitas Airlangga, Surabaya 60286, Indonesia.
2Faculty of Pharmacy, Universitas Halu Oleo, Kendari 93232, Indonesia.
3Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy,
Universitas Airlangga, Surabaya 60115, Indonesia.
4Natural Product Medicine Research and Development, Institute of Tropical Disease,
Universitas Airlangga, Surabaya 60115, Indonesia.
*Corresponding Author
Published In:
Volume - 16,
Issue - 2,
Year - 2023
ABSTRACT:
Safflower plant (Carthamus tinctorius L.) has been reported to be effective for treating people with measles, hypertension, stomach ache, malaria and cholesterol issues. This study aims to assess specific and non-specific parameters of characteristics for the ethanol extract of C. tinctorius L. flowers and its antioxidant properties. The specific parameters include the extract’s organoleptic properties, while the non-specific parameters include the drying shrinkage, microbial contamination content, ash content, as well as the extract’s solubility in water and ethanol according to Materia Medica Indonesia and Pharmacopeia Herbal Indonesia. An antioxidant activity assay was performed using the DPPH method. According to the results, the deep red, viscous organoleptic extract had a distinctive odor, as well as an astringent or chelate taste, and an Rf value of 0.79. Furthermore, the extract contained 0.12% of water-soluble compounds, 0.22% ethanol-soluble compounds, and several phytochemical groups, including flavonoids, saponins, triterpenoids, tannins, quinones, and steroids. According to the non-specific parameters, the extracts demonstrated 1.02%, 0.2237%, 0.96%, 0.23%, and 0.91% for weight, acid-insoluble ash content, dry shrinkage, ash content, and water content, respectively. Meanwhile, the microbial contaminant load was ? 1.0 × 10-1 colony/mL, alongside ? 1.0 × 10-1 colony/mL of mold/yeast. The C. tinctorius L. ethanol extract was observed to show significant antioxidant activities, evidenced by an IC50 which measured 2.511ppm, based on DPPH analysis. A similar outcome was also reported for the ethanol flower extract, which was further determined to fulfil both non-specific and specific standardization parameters.
Cite this article:
Rini Hamsidi, Myrna Adianti, Maya Septriana, Onny Priskila, Wahyuni, Adryan Fristiohady, Muhammad Hajrul Malaka, Vica Aspadiah, La Ode Muhammad Arlan, Karlies Sirupa Baka, Wiwied Ekasari, Aty Widyawaruyanti, Ahmad Fuad Hafid. Characteristic of the Ethanol Extract of Carthamus tinctorius L. Flowers and its Antioxidant Activity. Research Journal of Pharmacy and Technology 2023; 16(2):791-8. doi: 10.52711/0974-360X.2023.00136
Cite(Electronic):
Rini Hamsidi, Myrna Adianti, Maya Septriana, Onny Priskila, Wahyuni, Adryan Fristiohady, Muhammad Hajrul Malaka, Vica Aspadiah, La Ode Muhammad Arlan, Karlies Sirupa Baka, Wiwied Ekasari, Aty Widyawaruyanti, Ahmad Fuad Hafid. Characteristic of the Ethanol Extract of Carthamus tinctorius L. Flowers and its Antioxidant Activity. Research Journal of Pharmacy and Technology 2023; 16(2):791-8. doi: 10.52711/0974-360X.2023.00136 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-2-55
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