Author(s): Mohammmad Younis Dar, Md Sajid, Riehana Gani, Abdul Jalil Shah, Rampratap Meena, Seema Akbar, Tariq Ahmad Malik

Email(s): myounis985@gmail.com

DOI: 10.52711/0974-360X.2023.00926   

Address: Mohammmad Younis Dar*, Md Sajid, Riehana Gani, Abdul Jalil Shah, Rampratap Meena,Seema Akbar, Tariq Ahmad Malik
Regional Research Institute of Unani Medicine, Naseem Bagh, University of Kashmir Hazratbal, Srinagar, J&K - 190006, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 12,     Year - 2023


ABSTRACT:
Colchicum luteum (Liliaceae) belongs to genus Colchicum. The Liliaceae family consists of 280 genera and 4000 species, with diverse geographical locations. In the Kashmir valley, they are widely distributed. Colchicum luteum is a perennial plant with corms and starchy rhizomes. This drug holds a prime position in the Unani system of medicine due to presence of alkaloid colchicine, which is found to be effective in arthritis, gout, rheumatism, and used as a carminative, laxative, and aphrodisiac. Its hydro-alcoholic extract was screened for the presence of several phytoconstituents using preliminary phytochemical methods. The microscopy of the Colchicum luteum corm revealed the presence of Fragment of Vessels with Spiral and Annular Thickening, Parenchyma and Part of a Spirally Thickened Vessel, Calcium-Oxalate Crystal, Starch-Granule and Single-Fibre. Proximate analysis revealed that Colchicum luteum corm dry plant powder has a 2.6% Total Ash Value, 1.0% Acid Insoluble Ash Value, and 1.8% Water Soluble Ash Value. 10.6 percent was determined to be the loss on drying. Post treatment with various chemical agents, fluorescence examination of the powdered plant material was performed under UV light at 254 nm and visible light. The current study showed the microscopical characters, the preliminary phytochemical screening and the proximate analysis of the Colchicum luteum corm. Information collected from such studies can be used as benchmark in the quality control of this plant as herbal medicine for treatment of various diseases.


Cite this article:
Mohammmad Younis Dar, Md Sajid, Riehana Gani, Abdul Jalil Shah, Rampratap Meena,Seema Akbar, Tariq Ahmad Malik. Pharmacognostic and Phytochemical Characteristics of the Colchicum luteum Baker (Suranjan) growing wild in Kashmir Valley, India. Research Journal of Pharmacy and Technology. 2023; 16(12):5728-1. doi: 10.52711/0974-360X.2023.00926

Cite(Electronic):
Mohammmad Younis Dar, Md Sajid, Riehana Gani, Abdul Jalil Shah, Rampratap Meena,Seema Akbar, Tariq Ahmad Malik. Pharmacognostic and Phytochemical Characteristics of the Colchicum luteum Baker (Suranjan) growing wild in Kashmir Valley, India. Research Journal of Pharmacy and Technology. 2023; 16(12):5728-1. doi: 10.52711/0974-360X.2023.00926   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-12-27


REFERENCES:
1.    Rather, R.A., et al., The Assessment of Morphological Diversity of Colchicum luteum L., an Economically Important Threatened Medicinal Plant of Kashmir Himalaya. Sustainability, 2022. 14 (3): p.1327. doi.org/10.3390/su14031327
2.    Afsahul, K.M. F. Anjum, Suranjan (Colchicum autumnale L. and Merendra persica): great resolvent herbs of Unani system of medicine- a review. International Journal of Unani and Integrative Medicine, 2020. 4 (1): p.7-11. doi.org/10.33545/2616454X.2020.v4.i1a.115
3.    Khan, Asim Ali, et al. Majoon Suranjan: a potent Unani formulation for arthritis. Journal of Drug Delivery and Therapeutics. 2018; 8)6): 351-355. doi.org/10.22270/jddt. v8i6.2149
4.    Ng, S.W., et al., Simultaneous detection of 22 toxic plant alkaloids (aconitum alkaloids, solanaceous tropane alkaloids, sophora alkaloids, strychnos alkaloids and colchicines) in human urine and herbal samples using liquid chromatography–tandem mass spectrometry. Journal of Chromatography B, 2013; 942: 63-69. doi: 10.1016/j.jchromb.2013.10.020
5.    Rigante, D., et al., The pharmacologic basis of treatment with colchicines in children with familial Mediterranean fever. European Review for Medical and Pharmacological Sciences, 2006.10 (4): 173.
6.    Pırıldar, S.,et al., Chemical constituents of the different parts of Colchicum baytopiorum and their cytotoxicactivities on K562 and HL60 cell lines. Pharmaceutical Biology. 2010. 48(1): 32-39. doi:10.3109/13880200903029373
7.    Larsson, S. and N. Ronsted, Reviewing Colchicaceae alkaloids–perspectives of evolution on medicinal chemistry. Current Topics in Medicinal Chemistry. 2014. 14(2): 274-289.doi: 10.2174/1568026613666131216110417
8.    Evans, W.C., Trease and Evans' Pharmacognosy: Elsevier Health Sciences. 2009.
9.    Harborne, A., Phytochemical methods a guide to modern techniques of plantanalysis. Springer science & business media. 1998.
10.    Kokoski, C.J., R.J. Kokoski, and F.J. Slama, Fluorescence of powdered vegetable drugs under ultraviolet radiation. Journal of the American Pharmaceutical Association (Scientificed.). 1958. 47 (10): p.715-717.doi:10.1002/jps.3030380612
11.    Gupta, S., etal., Volatile (As and Hg) and non-volatile (Pb and Cd) toxic heavy metals analysis in rhizome of Zingiber officinale collected from different locations of North Western Himalayas by Atomic Absorption Spectroscopy. Food and Chemical Toxicology. 2010; 48 (10): 2966-2971. doi.org/10.1016/j.fct.2010.07.034
12.    WHO, G., WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues. 2007.
13.    Afla Test Instruction manual. 1999. (AflaTest). Pdf accessed on 06 Sep 2022,http://www.biotic.com.tw/index.files/GN-MC9508-5%20

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