Author(s): Ifuling Audrein Yansen, Theresia Indah Budhy, Alexander Patera Nugraha, Florentina Joestandari, Tengku Natasha Eleena binti Tengku Ahmad Noor

Email(s): alexander.patera.nugraha@fkg.unair.ac.id

DOI: 10.52711/0974-360X.2023.00895   

Address: Ifuling Audrein Yansen1, Theresia Indah Budhy2,3, Alexander Patera Nugraha2,4,5*, Florentina Joestandari6, Tengku Natasha Eleena binti Tengku Ahmad Noor7,8
1Graduate Student of Immunology, Post Graduate School, Universitas Airlangga, Surabaya 60115 Indonesia
2Immunology Study Program, Postgraduate School, Universitas Airlangga, Surabaya 60115, Indonesia
3Department of Oral and Maxillofacial Pathology, Faculty of Dental Medicine, Universitas Airlangga, Surabaya 60115, Indonesia
4Department of Orthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya 60115, Indonesia
5Graduate Student of Dental Health Science, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia
6Faculty of Dentistry, Institute of Health Bhakti Wiyata, Kediri, Indonesia
7Membership of Faculty of Dental Surgery, Royal Collage of Surgeon, Edinburgh University, United Kingdom
8Malaysian Armed Forces Dental Officer, 609 Armed Forces Dental Clinic, Kem Semenggo, Kuching, Saraw

Published In:   Volume - 16,      Issue - 11,     Year - 2023


ABSTRACT:
Background: Breast cancer or Carcinoma mammae is a malignancy that damage the gland ducts, and breast supporting tissues. Breast cancer is ranked first as a malignancy that often occurs in the world. The majority of women with breast cancer will have many surgeries. Chemotherapy is frequently used in conjunction with surgery. However, the side effects of chemotherapy drugs can damage healthy cells. Bidara leaf are one of the most promising sources of bioactive compounds for the pharmaceutical field in the treatment of breast cancer. Aims: This review article aims to describe the several types of Bidara leaf that contain compounds and anticancer activity that have potential as alternative treatments for breast cancer through narrative review. Review:This review article discusses several types of Bidara leaf and their anticancer activity. Conclusion: From the results of a journal review, it was found that several types of Bidara leaf with breast anticancer activity were Ziziphus spina christi, Zizyphus mauritiana, Ziziphus nummularia, with various activities such as cytotoxicity, antiproliferative, proapoptotic, and proinflammatory on the MCF-7 breast cancer cell line.


Cite this article:
Ifuling Audrein Yansen, Theresia Indah Budhy, Alexander Patera Nugraha, Florentina Joestandari, Tengku Natasha Eleena binti Tengku Ahmad Noor. Potential of Bidara Leaf as Adjunctive Therapy against Breast Cancer Cell Line: A Review. Research Journal of Pharmacy and Technology. 2023; 16(11):5532-5. doi: 10.52711/0974-360X.2023.00895

Cite(Electronic):
Ifuling Audrein Yansen, Theresia Indah Budhy, Alexander Patera Nugraha, Florentina Joestandari, Tengku Natasha Eleena binti Tengku Ahmad Noor. Potential of Bidara Leaf as Adjunctive Therapy against Breast Cancer Cell Line: A Review. Research Journal of Pharmacy and Technology. 2023; 16(11):5532-5. doi: 10.52711/0974-360X.2023.00895   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-11-89


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