Author(s):
Hrithik Shyam, Bhuvaneshwari. G, D. Aruna, P. Neelusree
Email(s):
bhuvaneshwarigunasekar@gmail.com
DOI:
10.52711/0974-360X.2023.00867 
Address:
Hrithik Shyam1, Bhuvaneshwari. G2*, D. Aruna2, P. Neelusree3
1CRRI - MBBS Student, Saveetha Medical College, Thandalam.
2Assistant Professor, Department of Microbiology, Saveetha Medical College, Thandalam,
3Professor and Head of the Department, Department of Microbiology, Saveetha Medical College, Thandalam.
*Corresponding Author
Published In:
Volume - 16,
Issue - 11,
Year - 2023
ABSTRACT:
Staphylococcus is a group of bacteria that comprises of more than 30 species of medical importance. Among which Staphylococcus aureus causes most infections. 60% of Healthcare associated infections were caused by Staphylococcus aureus. They cause many different types of infections like Skin infections, which are the most common types. They also cause Bacteremia, an infection of the bloodstream, which can lead to sepsis. Bone infections, Endocarditis, Food poisoning and Pneumonia were also commonly caused by this bacterium. In past one-decade Staphylococcus species is gaining resistance to the antibiotics which is commonly used and also to the higher level antibiotics. This study mainly emphasis upon the prevalence of these species in a tertiary care hospital in order to frame the antimicrobial stewardship policy. The samples were received from the different departments and antimicrobial susceptibility pattern was interpreted. All the clinical specimens yielding Staphylococcus species were included in this study. 63% of Staphylococcus species were isolated from Exudate specimen following by Urine, Respiratory and Blood. The prevalence of MRCONS and MRSA is higher among inpatients with varying susceptibility pattern. This requires periodical surveillance and stringent infection control practices. This retrospective study was conducted to evaluate the value of the antimicrobial stewardship team (AST) combined with infectious diseases consultation on management and outcomes of Staphylococcus infections in a tertiary-care center.
Cite this article:
Hrithik Shyam, Bhuvaneshwari. G, D. Aruna, P. Neelusree. Retrospective Study on the Prevelance of Antimicrobial susceptibility pattern of staphylococcus species among patients attending Tertiary Care Hospital. Research Journal of Pharmacy and Technology. 2023; 16(11):5354-7. doi: 10.52711/0974-360X.2023.00867
Cite(Electronic):
Hrithik Shyam, Bhuvaneshwari. G, D. Aruna, P. Neelusree. Retrospective Study on the Prevelance of Antimicrobial susceptibility pattern of staphylococcus species among patients attending Tertiary Care Hospital. Research Journal of Pharmacy and Technology. 2023; 16(11):5354-7. doi: 10.52711/0974-360X.2023.00867 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-11-61
REFERENCES:
1. Mohammed S, Nawaz U. Spectrum of Antimicrobial Susceptibility of E. coli and Staphylococcus aureus isolates from Clinical Samples. Research J. Pharm. and Tech. 2015; 8(10): 1399-1402. doi 10.5958/0974-360X.2015.00251.6
2. Ashok Kumar, N.P. Muralidharan. Screening of Nasal Carriers of Staphylococcus aureus in Dental Clinics. Research J. Pharm. and Tech. 2016; 9(10): 1650-1652. doi: 10.5958/0974-360X.2016.00332.2
3. Dilnessa T, Bitew A. Prevalence and antimicrobial susceptibility pattern of methicillin resistant Staphylococcus aureus isolated from clinical samples at Yekatit 12 Hospital Medical College, Addis Ababa, Ethiopia. BMC Infect Dis. 2016; 16: 398. Published 2016 Aug 9. doi:10.1186/s12879-016-1742-5
4. Mohammad Ali Mohaghegh. A Retrospective Study on the Prevalence And Antibiotic Resistance Pattern of Staphylococcus Aureus And Staphylococcus Epidermidis Among Patients Suspicious Of Bacteremia During. 2006 - 2011 3. e22930. doi/10.17795/ijep22930.
5. Saravanan Murugesan1, Sujina TK, Sajani Samuel, Sarath Ke, Parthiban Rudrapathy. A Retrospective Study On Methicillin-Resistant Staphylococci Prevalence In Cancer Patients At A Tertiary Care Cancer Centre. Asian Journal of Pharmaceutical and Clinical Research. 2021; 14(7): 82-85. doi:10.22159/ajpcr.2021.v14i7.41482.
6. Bezlon G., Shanmugha Sundhar D., Rinu Edwin R.E. Design and Stabilization of Natural Antibacterial Compound Allicin against Methicillin-Resistant Staphylococcus Aureus for Treatment as a Novel Antibiotic. Research J. Engineering and Tech. 2013; 4(4): 179-181. doi: 10.5958/2321-581X
7. Francois P, Pittet D, Bento M, et al. Rapid detection of methicillin-resistant Staphylococcus aureus directly from sterile or nonsterile clinical samples by a new molecular assay. J Clin Microbiol. 2003; 41(1): 254-260. doi:10.1128/JCM.41.1.254-260.2003
8. S Singh, A. Study on Coagulase-Negative Staphylococci Causing Blood Stream Infection At An Indian Tertiary Care Hospital: Prevalence, Antimicrobial Resistance And Molecular Characterisation. Indian Journal of Medical Microbiology. 2016; 34(4): 500-505. doi: 10.4103/0255-0857.195374.
9. Young BC, Wilson DJ. On the evolution of virulence during Staphylococcus aureus nasal carriage. Virulence. 2012; 3(5): 454-456. doi:10.4161/viru.21189
10. Sakshi Satyendranarayan Gupta. U.V Radiation Effect on Growth and Survival of Bacteria Staphylococcus aureus. Asian J. Pharm. Ana. 2021; 11(1): 27-28. doi: 10.5958/2231-5675.2021.00005.3
11. Lakshmi T. In Vitro Bactericidal Activity of Herbal Extracts against Coagulase Positive Staphylococcus intermedius – A Common Oral Pathogen in Animal Species. Research J. Pharm. and Tech. 2014; 7(2): 173-175. DOI: 10.5958/0974-360X
12. Wissam Zam, Rim Harfouch, Al Dwiri Mais, Khwanda Rand. Anti-Staphylococcus aureus efficacy of six natural honey samples originated from Syria. Res. J. Pharmacognosy and Phytochem. 2018; 10(1): 23-26. DOI: 10.5958/0975-4385
13. F. Mariyam Niyas, Dr. Gopinath P. Comparative study on detection of MRSA using oxacillin agar screening method, cefoxitin disc diffusion method and mecAgene by PCR among clinical isolates of Staphylococcus aureus. Research J. Pharm. and Tech 2016; 9(9): 1317-1320. doi: DOI: 10.5958/0974-360X.2016.00250.X
14. M. Deepigaa, Gopinath P. Detection of Vancomycin Resistance among Clinical Isolates of Staphylococcus aureus. Research J. Pharm. and Tech 2018; 11(2): 621-623. doi: 10.5958/0974-360X.2018.00115.4
15. K. Kavipriya, A. Maria Therese, A. Felicia Chitra. Effectiveness of Educational Intervention Programme on Knowledge and Behavioral Competence of Methicillin Resistance Staphylococcus Aureus among Nursing OfficersInt. J. Nur. Edu. and Research. 2019; 7(3):383-385. doi: 10.5958/2454-2660.2019.00086.3
16. Abalkhail, A.; Elbehiry, A. Methicillin-Resistant Staphylococcus aureus in Diabetic Foot Infections: Protein Profiling, Virulence Determinants, and Antimicrobial Resistance. Appl. Sci. 2022; 12:10803. https://doi.org/10.3390/ app122110803.
17. Refsahl K, Andersen BM. Clinically significant coagulase-negative staphylococci: identification and resistance patterns. J Hosp Infect. 1992; 22(1): 19-31. doi:10.1016/0195-6701(92)90127-8
18. Gurung S, Kafle S, Dhungel B, et al. Detection of OXA-48 Gene in Carbapenem-Resistant Escherichia coli and Klebsiella pneumoniae from Urine Samples. Infect Drug Resist. 2020; 13: 2311-2321. doi:10.2147/IDR.S259967
19. David Styers, Daniel, Sheehan, Patricia Hogan and Daniel F Sahm. Laboratory-Based Surveillance of Current Antimicrobial Resistance Patterns and trends Among Staphylococcus Aureus: Status In The United States. Ann Clin Microbiol Antimicrob.2006; 9(5): 2. https://doi.org/10.1186/1476-0711-5-2
20. S. Deepa, R. Bharathidasan, K.Kanimozhi, A. Panneerselvam. Bacteriological Profile of Surgical and Non-Surgical Wound Infections in a Tertiary Care Hospital. Research J. Pharm. and Tech. 2012; 5(6): 853-856. DOI: 10.5958/0974-360X