Author(s):
Abdul Rahman Wahid, Dzun Haryadi Ittiqo, Melati Permata Hati, Safwan Safwan, Myra Sulistia Nopianti, Siti Wardia Karim
Email(s):
rahman_apt@yahoo.co.id
DOI:
10.52711/0974-360X.2023.00768 
Address:
Abdul Rahman Wahid1*, Dzun Haryadi Ittiqo2, Melati Permata Hati2, Safwan Safwan1, Myra Sulistia Nopianti3, Siti Wardia Karim3
1Departement of Phytochemical and Pharmacognosy, Faculty of Health Sciences, University of Muhammadiyah Mataram, West Nusa Tenggara, Indonesia.
2Departement of Pharmaceutical, Faculty of Health Sciences, University of Muhammadiyah Mataram.
3Associate Degree, Faculty of Health Sciences, University of Muhammadiyah Mataram.
*Corresponding Author
Published In:
Volume - 16,
Issue - 10,
Year - 2023
ABSTRACT:
Red algae (Eucheuma spinosum) was reported has excellent antioxidant activity. It was collected from Gili Tangkong, Sekotong District, West Lombok, West Nusa Tenggara. The research aims to determine antioxidant activity of the gel form of red algae ethanol extract by DPPH (1,1-diphenyl-2-picrylhydrazil) method. The extract was prepared into gel formulate in various concentrations: F1(10%); F2(20%) and F3(30%) (w/w) by using combination carbopol 940 and HPMC as polymer bases. The physicochemical parameters of gel formulation (organoleptic, pH, spreadability, adhesion) were determined. Stability studies of gel have carried out for 21 days at viscosity and an antioxidant activity using the DPPH method. The results showed that all formulations complied with the required characteristics, which stability analysis did not change significantly in pH, organoleptic, consistency, adhesivity and spreadability during storage. Antioxidant activity of all formulas showed that the value of IC50 on F1 198.88 ppm (weak intensity: 151
Cite this article:
Abdul Rahman Wahid, Dzun Haryadi Ittiqo, Melati Permata Hati, Safwan Safwan, Myra Sulistia Nopianti, Siti Wardia Karim. Physical Stability of Gel of Read Algae (Eucheuma spinosum) Extract and Evaluation of its Antioxidant effect. Research Journal of Pharmacy and Technology 2023; 16(10):4729-6. doi: 10.52711/0974-360X.2023.00768
Cite(Electronic):
Abdul Rahman Wahid, Dzun Haryadi Ittiqo, Melati Permata Hati, Safwan Safwan, Myra Sulistia Nopianti, Siti Wardia Karim. Physical Stability of Gel of Read Algae (Eucheuma spinosum) Extract and Evaluation of its Antioxidant effect. Research Journal of Pharmacy and Technology 2023; 16(10):4729-6. doi: 10.52711/0974-360X.2023.00768 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-10-38
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