Author(s): Anita Kumari, Renu Khedar, Taruna Pandey, R V Singh, Nighat Fahmi

Email(s): ,

DOI: 10.52711/0974-360X.2023.00764   

Address: Anita Kumari, Renu Khedar, Taruna Pandey, R V Singh, Nighat Fahmi*
Department of Chemistry, University of Rajasthan, Jaipur, India – 302004.
*Corresponding Author

Published In:   Volume - 16,      Issue - 10,     Year - 2023

A green, straightforward, microwave-assisted method of synthesizing organogermanium complexes derived from 1-acetylferrocenehydrazinecarboxamide (AcSCZH) and 1-acetylferrocenehydrazinecarbothioamide (AcTSCZH) have been reported. For structural elucidation, elemental analysis, melting point measurements, and a mix of UV, IR, and 1H NMR spectroscopy methods were used to describe all of the produced compounds. According to physicochemical and spectroscopic investigations, the ligands are coupled to the Ge (IV) by azomethine nitrogen and the thiolicsulphur atom/enoloic oxygen atom. A trigonal-bipyramidal structure has been assigned to 1:1 germanium (IV) complexes, while an octahedral structure has been assigned to 1:2 germanium (IV) complexes. Antibacterial and antifungal activity of the compounds were investigated in vitro against human pathogenic bacteria and fungi respectively. The complexes' DNA cleavage abilities and antioxidant properties were also investigated. The present research work highlights the current progress in the development of germanium complexes as novel anti-oxidant and DNA cleavage agents.

Cite this article:
Anita Kumari, Renu Khedar, Taruna Pandey, R V Singh, Nighat Fahmi. Microwave assisted Facile Green Synthesis, Characterization and Biological Evaluation of Organogermanium (IV) complexes. Research Journal of Pharmacy and Technology 2023; 16(10):4703-0. doi: 10.52711/0974-360X.2023.00764

Anita Kumari, Renu Khedar, Taruna Pandey, R V Singh, Nighat Fahmi. Microwave assisted Facile Green Synthesis, Characterization and Biological Evaluation of Organogermanium (IV) complexes. Research Journal of Pharmacy and Technology 2023; 16(10):4703-0. doi: 10.52711/0974-360X.2023.00764   Available on:

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