Author(s):
Pramod Kumar Adusumilli, Bala Sowmya Samanthula, Dharini Boopathi, Deepalakshmi Mani
Email(s):
deepapharmacy@jssuni.edu.in
DOI:
10.52711/0974-360X.2023.00732 
Address:
Pramod Kumar Adusumilli, Bala Sowmya Samanthula, Dharini Boopathi, Deepalakshmi Mani
1Department of Pharmacy Practice, Ramaiahuniversity of Applied Sciences, Bangalore 560054, India.
2Department of Pharmacy Practice, Chebrolu Hanumaiah Institute of Pharmaceutical Sciences,
Guntur, Andhra Pradesh, India.
3ADR Monitoring Centre, Karpagam Faculty of Medical Sciences and Research, Coimbatore.
4Pharmacovigilance Programme of India (NCC-PvPI), Indian Pharmacopoeia Commission,
Department of Pharmacy Practice, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Ooty, Nilgiris, Tamil Nadu, India.
*Corresponding Author
Published In:
Volume - 16,
Issue - 10,
Year - 2023
ABSTRACT:
Lennox gastaut syndrome (LGS) is a childhood onset severe epileptic encephalopathy with multiple seizures types usually refractory to pharmacological management. Despite the availability of various anti-epileptic drugs, children with LGS continue to have seizures. LGS refractory to pharmacological treatment leads to poor prognoses like severe intellectual disability and persisting seizures. Dietary treatment along with anti – epileptics can result in less patient exposure to drugs. In this report, we present a case of 11 years old child of LGS with worsening of intellectual disability. Adapting non pharmacological treatment can reduce the patient exposure to drugs and seizure control. Surgical options are recommended when patient doesn’t respond to anti – epileptic drugs. Corpus callosotomy and vagus nerve stimulation are most recent advances in surgical treatment of LGS. Although more data are needed to confirm efficacy of non pharmacological options, in many cases they resulted in complete reduction of seizure.
Cite this article:
Pramod Kumar Adusumilli, Bala Sowmya Samanthula, Dharini Boopathi, Deepalakshmi Mani. Case Report of Lennoxgastaut Syndrome and An Overview of its Non-Pharmacological Treatments. Research Journal of Pharmacy and Technology 2023; 16(10):493-7. doi: 10.52711/0974-360X.2023.00732
Cite(Electronic):
Pramod Kumar Adusumilli, Bala Sowmya Samanthula, Dharini Boopathi, Deepalakshmi Mani. Case Report of Lennoxgastaut Syndrome and An Overview of its Non-Pharmacological Treatments. Research Journal of Pharmacy and Technology 2023; 16(10):493-7. doi: 10.52711/0974-360X.2023.00732 Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-10-2
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