Author(s): Sowmya Cherukuri, Anitha Paramanayagam, Prabakaran R, Mayakannan M, Lavakumar Vuppalapati

Email(s): csowmya05@gmail.com

DOI: 10.52711/0974-360X.2023.00046   

Address: Sowmya Cherukuri1, Anitha Paramanayagam2*, Prabakaran R3, Mayakannan M3, Lavakumar Vuppalapati3
1Assistant Professor, Dept of Pharmaceutics, Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai – 600116, Tamilnadu, India.
2Associate Professor, Dept of Pharmacognosy, St. Mariam College of Pharmacy, Tirunalveli - 627851, Tamilnadu, India.
3Dept of Pharmacology, Arulmigu Kalasalingam College of Pharmacy, Anand Nagar, Srivilliputtur - 626126, Tamilnadu, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 1,     Year - 2023


ABSTRACT:
The current study was aimed to evaluate the wound healing activity of ethyl acetate extract of fruit peels of Citrus aurantium. An ethyl acetate extract of fruit peel of Citrus aurantium was loaded into an ointment base with three different concentrations (0.25% w/w, 0.5% w/w and 1%w/w) and tested for wound healing activity using excision wound model by measuring the healing area and dermal toxicity. Wound healing activity and histopathology studies confirmed that all the tested three concentrations of extract accelerate the wound healing process by decreasing the surface area of the wound and increases the muscle tensile strength. Out of tested ointments, 5% w/w concentration showed comparative activity with the standard. Hence, natural Citrus aurantium peel-based ointment is an alternative ointment in wound healing.


Cite this article:
Sowmya Cherukuri, Anitha Paramanayagam, Prabakaran R, Mayakannan M, Lavakumar Vuppalapati. Evaluation of Cutaneous Wound Healing Activity of Citrus aurantium Fruit Peel Extract-based Ointment in Albino Rats. Research Journal of Pharmacy and Technology 2023; 16(1):250-4. doi: 10.52711/0974-360X.2023.00046

Cite(Electronic):
Sowmya Cherukuri, Anitha Paramanayagam, Prabakaran R, Mayakannan M, Lavakumar Vuppalapati. Evaluation of Cutaneous Wound Healing Activity of Citrus aurantium Fruit Peel Extract-based Ointment in Albino Rats. Research Journal of Pharmacy and Technology 2023; 16(1):250-4. doi: 10.52711/0974-360X.2023.00046   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-1-46


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