Author(s): Strelyaeva A. V., Stoyanova Ya. V., Kuznetsov R. M., Strelyaev N. D., Vaskova L. B., Lazareva Yu. B., Bobkova N. V., Prostodusheva T. V., Antsyshkina A. M., Gulyakin I. D.

Email(s): docstrelaeva@mail.ru , yana.v.krivda@gmail.com , roman_m_kuznetsov@rambler.ru , docstrelaeva@mail.ru , vaskova_l_b@staff.sechenov.ru , lazareva_yu_b@staff.sechenov.ru , –bobkovamma@mail.ru , prtatvl@yandex.ru , allants@mail.ru , ilya.gulyakin@yandex.ru

DOI: 10.52711/0974-360X.2023.00042   

Address: Strelyaeva A. V., Stoyanova Ya. V.*, Kuznetsov R. M., Strelyaev N. D., Vaskova L. B., Lazareva Yu. B., Bobkova N. V., Prostodusheva T. V., Antsyshkina A. M., Gulyakin I. D.
Sechenov First Moscow State Medical University (Sechenov University).
*Corresponding Author

Published In:   Volume - 16,      Issue - 1,     Year - 2023


ABSTRACT:
Due to the increase in allergic reactions to synthetic drugs, there has been a demand to expand the range of medications based on medicinal plant-based raw materials. Tanacetum vulgare is a medicinal plant that contains large amount of biologically active substances and is widely used in traditional and modern medicine. The aim of the study was to elaborate the chemical composition and pharmacological activity of extracts (the essential oil, the tincture and the petroleum extract) derived from medicinal plant-based raw materials of Tanacetum vulgare. The object of the study was essential oil obtained from fresh Tanacetum vulgare grass, petroleum extraction of Tanacetum vulgare and tincture obtained from Tanacetum vulgare using the maceration method. The qualitative composition of essential oil, tincture and petroleum extraction was determined by chromatography-mass spectrometry. In essential oil, regardless of the preparation method, the maximal antioxidant activity is shown by the petroleum extraction from the grass of Tanacetum vulgare. Hydrodistillation was performed using a Ginsberg method or hydrodistillation using a Cleveger method. More than 80 compounds have been identified; more than 100 compounds have been identified in tincture, and more than 150 compounds have been identified in petroleum extraction,such as camphor, borneol, ascaridiol, isoaromadendrene, cubenol, limonene, carvacrol, pinene, cineol, terpineol and chrysanthenon. Tincture and essential oil exhibit antioxidant activity slightly lower than petroleum extraction.


Cite this article:
Strelyaeva A. V., Stoyanova Ya. V., Kuznetsov R. M., Strelyaev N. D., Vaskova L. B., Lazareva Yu. B., Bobkova N. V., Prostodusheva T. V., Antsyshkina A. M., Gulyakin I. D.. Comparative Study of Chemical Composition and Antioxidant activity of Essential oil, Tincture and Petroleum extraction from Medicinal plant-based raw material of Tanacetum vulgare. Research Journal of Pharmacy and Technology 2023; 16(1):229-5. doi: 10.52711/0974-360X.2023.00042

Cite(Electronic):
Strelyaeva A. V., Stoyanova Ya. V., Kuznetsov R. M., Strelyaev N. D., Vaskova L. B., Lazareva Yu. B., Bobkova N. V., Prostodusheva T. V., Antsyshkina A. M., Gulyakin I. D.. Comparative Study of Chemical Composition and Antioxidant activity of Essential oil, Tincture and Petroleum extraction from Medicinal plant-based raw material of Tanacetum vulgare. Research Journal of Pharmacy and Technology 2023; 16(1):229-5. doi: 10.52711/0974-360X.2023.00042   Available on: https://rjptonline.org/AbstractView.aspx?PID=2023-16-1-42


REFERENCES:
1.    FouziaTehseen, Syed SafiullahGhori, RuqyaKhatoon, Jabeen Sultana, MdSadath Ali, Maria Mahveen. In vitro Antihelmintic Evaluation of a Novel Polyherbal Formulation. Research J. Pharm. and Tech 2020; 13(2):636-638.
2.    K. О. Kalko, O. Ya. Mishchenko, L. V. Derymedvid, M. Yu. Zolotaikina, Т. M. Gontova, V. V. Mashtaler, S. A. Kutsenko. A Screening Study of Hepatoprotective Activity of Liquid Extract from Common Tansy Tanacetum vulgare L. Herb in the setting of Subchronic Hepatitis in Rats. Research J. Pharm. and Tech 2018; 11(10): 4393-4396.             
3.    Saumya Subramanian, PadmajaAnanth Shenoy, Vasudev Pai. Antimicrobial activity of some Essential oils and Extracts from Natural sources on Skin and Soft tissue infection causing microbes: An In-vitro Study. Research Journal of Pharmacy and Technology. 2021; 14(7):3603-9.
4.    Maharaja P, Sengottuvel T, Aarthi A, Gopalasatheeskumar K. Review on Antioxidant and Hepatoprotective activity of Medicinal plants against Paracetamol Induced animal model. Res. J. Pharmacognosy and Phytochem. 2020; 12(2): 114-119.
5.    Devrnja N, et al. In vitro cultivation of tansy (Tanacetum vulgare L.): a tool for the production of potent pharmaceutical agents. Protoplasma. 2021 May;258(3):587-599. doi: 10.1007/s00709-020-01588-9. Epub 2020 Nov 27.
6.    Kleine S, Müller C. Differences in shoot and root terpenoid profiles and plant responses to fertilisation in Tanacetum vulgare. 2018; Phytochemistry, 96, 123–131. doi:10.1016/j.phytochem.2013.09.0
7.    Lahlou S, et al. Acute and chronic toxicity of a lyophilised aqueous extract of Tanacetum vulgare leaves in rodents. Journal of Ethnopharmacology. 2008; 117(2), 221–227. doi:10.1016/j.jep.2008.01.024
8.    Aditi Bahadur, K S Chandrashekar, Vasudev Pai. Formulation and Development of Polyherbal mosquito Repellent Incense Sticks. Research J. Pharm. and Tech. 2020; 13(1): 124-128.
9.    B. R. Malathy, SweetlinAjitha P, Sangeetha K. S, SwethaThampy, Kamala G. Antimicrobial activity of Commercial essential oils on human pathogens. Research Journal of Pharmacy and Technology. 2021; 14(8):4440-4.
10.    C. S. Kandasamy, Sai Lohit Ch., R. Siva Kumar, V. Gopal, Chandini, R. Nair, R. Venkatanarayanan. Analysis of Crude Drugs Present In the Hepatoprotective Polyherbal Formulation by HPTLC Technique. Research J. Pharmacognosy and Phytochemistry 2011; 3(6): 261-265.
11.    Rupali C. Umredkar, Pankaj R. Dhapake. Standardisation and in Vitro Evaluation of Flavonide Containing Medicinal Plants for its Hepatoprotective Activity - Review Article. Res. J. Pharm. Dosage Form. & Tech. 2017; 9(2): 71-82.
12.    Paderin NM, et al. Effect of pectin of tansy, Tanacetum vulgare L., on feeding behaviour and food intake in mice. Journal of Functional Foods.2018; 47, 66–71. doi:10.1016/j.jff.2018.05.040
13.    Puk K, Guz L. Parasiticidal effects of Tanacetum vulgare extract against Ichthyophthirius multifiliis. Pol J Vet Sci. 2021 Mar; 24(1):159-161. doi: 10.24425/pjvs.2021.136805.
14.    Radulović NS, et al. Toxic essential oils. Part V: Behaviour modulating and toxic properties of thujones and thujone-containing essential oils of Salvia officinalis L., Artemisia absinthium L., Thuja occidentalis L. and Tanacetum vulgare L. Food and Chemical Toxicology, 2017. 105, 355–369. doi:10.1016/j.fct.2017.04.044
15.    Dinesh SangarranRamachandram, V. Chitra, Rini. R. Correlation of Anti-oxidant, Anti-angiogenic, and Cytotoxic activity of Tanacetum parthenium compared with Amlodipine using Chorioallantoic membrane Assay. Research J. Pharm. and Tech. 2020; 13(4):1665-1671.
16.    Wolf VC, et al. Genetic and chemical variation of Tanacetum vulgare in plants of native and invasive origin. Biological Control, 2012. 61(3), 240–245. doi:10.1016/j.biocontrol.2012.01
17.    Naima Boukraa, SegniLadjel, Mohamed Bilal Goudjil, Amar Eddoud, Kifah Waleed Mustafa Sanori. Chemical compositions, Fumigant and Repellent Activities, of Essential oils from three Indigenous medicinal plants and their mixture, against stored grain pest, Triboliumcastaneum (Herbst) (Coleoptera: Tenebrionidae). Asian J. Research Chem. 2020; 13(6):455-464.

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