Author(s): Arpan K. Tripathi, Rupesh Soni, Shekhar Verma


DOI: 10.52711/0974-360X.2022.00721   

Address: Arpan K. Tripathi*, Rupesh Soni, Shekhar Verma
1Research Scholer, Department of Pharmacy, Mandsaur University, (M.P).
2Mandsaur University Campus, Mandsaur (M.P), India.
3University College of Pharmacy, Pt. Deendayal Upadhyaya Memorial Health Science and Ayush University of Chhattisgarh, Raipur (C.G), India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 9,     Year - 2022

In the current investigation, made endeavours to audit on a pharmacological movement of Mimosa pudica (Linn.) having a grade with family mimisace. Mimosa pudica (Linn.) is a swarming yearly or enduring herb. It has been documented as lajjalu in Ayurveda. It is called the delicate Plant, humble Plant, disgrace plant, resting grass, contactmenot, namaskari in Sanskrit, chuimui, lajwanti, snoozing grass, unstable Plant, humble Plant, hesitant Plant, get in touch with me not, and various names. The whole Plant of Mimosa pudica (Linn.) is beneficial for different pharmacological and natural exercises. For the most part, roots and leaves of Mimosa pudica (Linn.) are demonstrated the most excellent pharmacological action as hostile to the diabetic, counteragent, antihepatotoxic, cancer prevention agent, and wound recuperating movement, diuretic, anticancer, anticonvulsant. The herb has been used traditionally for ages to treat urogenital disorders, piles, dysentery, sinus, and applied on wounds. This work explores and compiles the different pharmacognostic and pharmacological aspects of the action plant M. pudica reported to date.

Cite this article:
Arpan K. Tripathi, Rupesh Soni, Shekhar Verma. A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds of Mimosa pudica (Linn.). Research Journal of Pharmacy and Technology. 2022; 15(9):4293-9. doi: 10.52711/0974-360X.2022.00721

Arpan K. Tripathi, Rupesh Soni, Shekhar Verma. A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds of Mimosa pudica (Linn.). Research Journal of Pharmacy and Technology. 2022; 15(9):4293-9. doi: 10.52711/0974-360X.2022.00721   Available on:

1.    Gandhiraja N, Sriram S, Meenaa V, Srilakshmi JK, Sasikumar C, Rajeswari R. Phytochemical screening and antimicrobial activity of the plant extracts of Mimosa pudica L. against selected microbes. Ethnobotanical leaflets. 2009; 2009(5):8.
2.    Roblin G. Mimosa Pudica: A Model for the Study of The Excitability IN PLANTS. Biological Reviews. 1979; 54(2)
3.    Patel SP. Anti-urolithiatic activity of extracts of plant-mimosa pudica l. In rats (Doctoral dissertation).
4.    Ahmad H, Sehgal S, Mishra A, Gupta R. Mimosa pudica L. (Laajvanti): An overview. Pharmacognosy Reviews. 2012; 6(12)
5.    Goli.Venkateshwarlu, Ragya Eslavath, Santhosh. Anasuri, Gutha. Suma, Kasireddy.Swapna, E.Rajeshwari. Mimosa pudica-an Important Medicinal Plant: A Review of Its Folklore Medicine and Traditional Uses. Asian J. Res. Pharm. Sci. 4(3): July-Sept. 2014; Page 151-152.
6.    Patwardhan B, Warude D, Pushpangadan P, Bhatt N. Ayurveda and traditional Chinese medicine: a comparative overview. Evidence-based complementary and alternative medicine. 2005 Dec 1; 2(4):465-73.
7.    Muhammad G, Hussain MA, Jantan I, Bukhari SNA. Mimosa pudica L., a High-Value Medicinal Plant as a Source of Bioactives for Pharmaceuticals. Comprehensive Reviews in Food Science and Food Safety. 2016; 15(2)
8.    Srinivas TL, Lakshmi SM, Shama SN, Reddy GK, Prasanna KR. Medicinal plants as anti-ulcer agents. Journal of Pharmacognosy and Phytochemistry. 2013; 2(4):91-7.
9.    Andallu B, Radhika B. Hypoglycemic, diuretic and hypocholesterolemic effect of winter cherry (Withania somnifera, Dunal) root.
10.    Huffman MA, Seifu M. Observations on the illness and consumption of a possibly medicinal plant Vernonia amygdalina (Del.), by a wild chimpanzee in the Mahale Mountains National Park, Tanzania. Primates. 1989; 30(1):51-63.
11.    Anwar F, Latif S, Ashraf M, Gilani AH. Moringa oleifera: A food plant with multiple medicinal uses. Phytotherapy Research. 2007; 21(1):17-25.
12.    Mohan G, Anand SP, Doss A. Efficacy of aqueous and methanol extracts of Caesalpinia sappan L. and Mimosa pudica L. for their potential antimicrobial activity. South Asian Journal of . Biological Science 2011; 1(2):48-57.
13.    Joseph B, George J, Mohan J. Pharmacology and traditional uses of Mimosa pudica. International journal of pharmaceutical sciences and drug research. 2013; 5(2):41-4.
14.    Chaudhury S, Singh H, Bharati KA. Quantitative analyses on ethnogynecological remedies used by Lodhas of Paschim Medinipur district, West Bengal, India.
15.    Venkateshwarlu Goli, Kanakam Vijay Bhaskar, Sravan Prasad Macharla, Jimmidi.Bhaskar, P. Suvarna Devi, T. Ramchander. Effects of Anti-Inflammatory Activity of Mimosa pudica. Asian J. Pharm. Res. 1(3): July-Sept. 2011; Page 69-71.
16.    Sharma J, Gairola S, Sharma YP, Gaur RD. Ethnomedicinal plants used to treat skin diseases by Tharu community of district Udham Singh Nagar, Uttarakhand, India. Journal of Ethnopharmacology. 2014, 2; 158:140-206.
17.    Ngo Bum E, Dawack DL, Schmutz M, Rakotonirina A, Rakotonirina SV, Portet C, et al. Anticonvulsant activity of Mimosa pudica decoction. Fitoterapia. 2004; 75 (3):309-14.
18.    Ahmed S, Hasan MM, Mahmood ZA. In vitro urolithiasis models: An evaluation of prophylactic management against kidney stones. Journal of Pharmacognosy and Phytochemistry. 2016; 1; 5(3):28.
19.    Swati Paul, Dibyajyoti Saha, Srikanta Chowdhury. Pharmacognostic Studies on Aerial Part of Methanolic Extract of Mimosa Pudica. Asian J. Pharm. Tech. 2(3): July-Sept. 2012; Page 101-103.
20.    Azmi L, Singh MK, Akhtar AK. Pharmacological and biological overview on Mimosa pudica (Linn.) International journal of pharmacy & life sciences. 2011 Nov 1; 2(11).
21.    Singh K, Kumar A, Langyan N, Ahuja M. Evaluation of Mimosa pudica seed mucilage as sustained-release excipient. AAPS PharmSciTech. 2009; 10(4):1121-7.
22.    Nikita Saraswat, Pranay Wal, Rashmi Saxena Pal, Ankita Wal, Yogendra Pal, Akanksha Pandey. Pharmacognostic Evaluation and Standardization of the leaves of Mimosa pudica, leaves of Murraya koenigii and root of Asparagus racemosus. Research J. Pharm. and Tech. 2020; 13(12):5743-5748. 10.5958/0974-360X.2020.01000.8
23.    Lim TK. Mimosa pudica. In: Lim TK, editor. Edible Medicinal And Non-Medicinal Plants: Volume 7, Flowers. Dordrecht: Springer Netherlands; 2014. p. 821-35.
24.    Johnson K, Narasimhan G, Krishnan C. Mimosa pudica Linn-a shyness princess: a review of its plant movement, active constituents, uses and pharmacological activity. Int J Pharm Sci Res. 2014; 1; 5(12):5104. 10.13040/IJPSR.0975-8232.5(12).5104-18
25.    Molina M, Contreras CM, Tellez-Alcantara P. Mimosa pudica may possess antidepressant actions in the rat. Phytomedicine. 1999 Nov 1; 6(5):319-23.
26.    Weintraub M. Leaf movements in Mimosa pudica L. The New Phytologist. 1952 Jan 1; 50(3):357-82.
27.    Mapala K, Pattabi M. Mimosa pudica flower extract mediated green synthesis of gold nanoparticles. Nano World Journal. 2017 Jul 11; 3(2):44-50. 10.17756/nwj.2017-045
28.    Chauhan BS, Johnson DE. Germination, emergence, and dormancy of Mimosa pudica. Weed Biology and Management. 2009; 9(1):38-45.
29.    Bhat DM, Murali KS. Phenology of understorey species of tropical moist forest of Western Ghats region of Uttara Kannada district in South India. Current Science. 2001; 10:799-805.
30.    Miléo LJ, Silva JF, Albertino SM, Leite BN, Menezes DS, Santos AF. Phytosociology of weeds in cultivation of two varieties of cassava1. Planta Daninha. 2016; 34:267-76.
31.    Jennifer Suganthi S., Uma Devi P., Suba Kanmani S. Free Radical Scavenging Potential and HPTLC profile of Mimosa pudica. Research J. Pharm. and Tech. 4(7): July 2011; Page 1090-1094.
32.    Souza Filho AP, Alves SM, Figueiredo FJ, Dutra S. Germinação de sementes de plantas daninhas de pastagens cultivadas: Mimosa pudica e Ipomoea asarifolia. Planta Daninha. 2001; 19:23-31.
33.    Ahmad H, Sehgal S, Mishra A, Gupta R. Mimosa pudica L.(Laajvanti): an overview. Pharmacognosy reviews. 2012; 6(12):115.
34.    Yuan K, Lü JL, Yin MW. Chemical constituents of C-glycosylflavones from Mimosa pudica. Yao xue xue bao= Acta pharmaceutica Sinica. 2006; 1; 41(5):435-8.
35.    Oogai S, Fukuta M, Watanabe K, Inafuku M, Oku H. Molecular characterization of mimosinase and cystathionine β-lyase in the Mimosoideae subfamily member Mimosa pudica. Journal of plant research. 2019; 132(5):667-80.
36.    Choudhury MD, Chakrabarti P. Cellular and chloroplast lipid composition of the leaves of Mimosa pudica. Phytochemistry. 1980.1; 19(4):519-23.
37.    Yuan K, Lu JL, Jia A, Zhu JX. Two new C-glycosylflavones from Mimosa pudica. Chinese Chemical Letters. 2007; 1; 18(10):1231-4.
38.    Ghosh R, Biswas S, Roy S. An apyrase from Mimosa pudica contains N5, N10‐methenyl tetrahydrofolate and is stimulated by light. European journal of biochemistry. 1998; 15; 258(3):1009-13.
39.    Vinutha B, Prashanth D, Salma K, Sreeja SL, Pratiti D, Padmaja R, Radhika S, Amit A, Venkateshwarlu K, Deepak M. Screening of selected Indian medicinal plants for acetylcholinesterase inhibitory activity. Journal of ethnopharmacology. 2007; 19; 109(2):359-63.
40.    Leshem YY. Plant membranes: A biophysical approach to structure, development and senescence. Springer Science & Business Media; 2013 Mar 9.
41.    Pande M, Pathak A. Preliminary pharmacognostic evaluations and phytochemical Studies on roots of Mimosa pudica (lajvanti). International Journal of Pharmaceutical Sciences Review and Research.2010; 1(1):50-2.
42.    Rajendran R, Krishnakumar E. Hypolipidemic activity of chloroform extract of Mimosa pudica leaves. Avicenna Journal of Medical Biotechnology. 2010; 2(4):215.
43.    Eloziia N, Kumar N, Kothiyal P, Deka P, Nayak BK. A review on antidepressant plants. Journal of Pharmacy Research. 2017;11(5):382-96. doi 10.22376/ijpbs/lpr.2020.10.5.L180-185
44.    Shaikh Z, Roy SP, Patel P, Gohil K. Medicinal value of Mimosa pudica as an anxiolytic and antidepressant: a comprehensive review. World journal of pharmacy and pharmaceutical sciences. 2016; 13; 5:420-32.
45.    Goli V, Bhaskar KV, Macharla SP, Bhaskar J, Devi PS, Ramchander T. Effects of anti-Inflammatory activity of Mimosa pudica.International journal of basic and clinical pharmacy. 2011;1 3 :69-71.
46.    Kashmira JG, Mayuri AL, Varsha MS. A comprehensive review on 'Mimosa pudica': A potential herbal panacea. Journal of Biologically Active Products from Nature. 2011;1;1(5-6):285-92.
47.    Bum EN, Dawack DL, Schmutz M, Rakotonirina A, Rakotonirina SV, Portet C, Jeker A, Olpe HR, Herrling P. Anticonvulsant activity of Mimosa pudica decoction. Fitoterapia. 2004;1;75(3-4):309-14.
48.    Naveen A, Mannala S, Jayasree T, Kumar KV, Nagesh C, Narapogu V. Evaluation of anticonvulsant activity of alcoholic extract of Mimosa pudica in Swiss albino rats. Journal of Chemical and Pharmaceutical Research. 2014;6(4):1175-9.
49.    Goli V, Kanakam V, Pavankumar G, Kirankumr P, Harishbabu K, Ravi M. Wound healing activity of Mimosa pudica in albino wistar rats. Journal of Chemical and Pharmaceutical Research. 2011;3(5):56-60.
50.    Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH. Evaluation of wound healing activity of root of Mimosa pudica. Journal of ethnopharmacology. 2009 ;15;124(2):311-5.
51.    Kannan S, Aravinth S, Sam E, Kumar J, Saminathan K, Suthakaran R. Wound healing activity of Mimosa pudica Linn formulation. International Journal of PharmTech Research. 2009; 11(4):1554-8.
52.    Tamilarasi T, Ananthi T. Phytochemical Analysis and Anti Microbial Activity of Mimosa pudica (Linn.) Research Journal of Chemical Sciences; 2012; 2231:606X.
53.    Neela FA, Sonia IA, Shamsi S. Antifungal activity of selected medicinal plant extract on Fusarium oxysporum Schlechtthe causal agent of fusarium wilt disease in tomato. American Journal of Plant Sciences. 2014; 7; 2014.
54.    Digrak M, Alma MH, Ilçim A, Sen S. Antibacterial and antifungal effects of various commercial plant extracts. Pharmaceutical Biology. 1999; 1; 37(3):216-20.
55.    Sutar NG, Sutar UN, Behera BC. Antidiabetic activity of the leaves of Mimosa pudica (Linn.) in albino rats. Journal of herbal medicine and toxicology. 2009; 3(1):123-6.
56.    Yupparach P, Konsue A. Hypoglycemic and hypolipidemic activities of ethanolic extract from Mimosa pudica L. in normal and streptozotocin-induced diabetic rats. Pharmacognosy Journal. 2017; 9(6).
57.    Pandey P, Kang S, Maheshwari DJCS. Isolation of endophytic plant growth promoting Burkholderia sp. MSSP from root nodules of Mimosa pudica. Current Science 2005:177-80.
58.    Rajendiran D, Kandaswamy S, Sivanesan S, Radhakrishnan S, Gunasekaran K. Potential antidiabetic effect of Mimosa pudica leaves extract in high fat diet and low dose streptozotocin-induced type 2 diabetic rats. International Journal of Biology Research. 2017; 2(4):55-62.
59.    Tunna TS, Ahmed QU, Uddin AB, Sarker M, Islam Z. Weeds as alternative useful medicinal source: Mimosa pudica (Linn.) on diabetes mellitus and its complications. In Advanced Materials Research 2014; 995: 49-59).
60.    Rekha Rajendran, S Ruby. Diuretic and Laxative Activities of Methanol Extract of Mimosa pudica Leaves. Research J. Pharm. and Tech. 3(2): April- June 2010; Page 556-558.
61.    Ueda M, Yamamura S. Leaf-closing substance of Mimosa pudica L.; chemical studies on another leaf-movement of mimosa II. Tetrahedron Letters. 1999; 9; 40(15):2981-4.
62.    Baghel A, Rathore DS, Gupta V. Evaluation of diuretic activity of different extracts of Mimosa pudica (Linn.) Pakistan journal of biological sciences. 2013 Oct 1; 16(20):1223-5.
63.    Sangma TK, Meitei UD, Sanjenbam R, Khumbongmayum S. Diuretic property of aqueous extract of leaves of Mimosa pudica (Linn.) on experimental albino rats. Journal of Natural Products. 2010; 3(2010):172-8.
64.    Meenatchisundaram S, Michael A. Preliminary studies on antivenom activity of Mimosa pudica root extracts against Russell's viper and saw scaled viper venom by in vivo and in vitro methods. Pharmacologyonline. 2009; 2:372-4.
65.    Sanaye MM, Joglekar CS, Pagare NP. Mimosa-A brief overview. Journal of Pharmacognosy and Phytochemistry. 2015 Jul 1; 4(2).
66.    Nishijima CM, Rodrigues CM, Silva MA, Lopes-Ferreira M, Vilegas W, Hiruma-Lima CA. Anti-hemorrhagic activity of four Brazilian vegetable species against Bothrops jararaca venom. Molecules. 2009; 14(3):1072-80.
67.    Meenatchisundaram S, Sindhu MK. In Vivo and In Vitro Studies on Neutralizing Effects of Acorus calamus and Withania somnifera root extracts against Echis carinatus venom. Iranian journal of pharmacology and therapeutics (2011): 26-30.
68.    Girish K, Mohanakumari HP, Nagaraju S, Vishwanath B, Kemparaju K. Hyaluronidase and protease activities from Indian snake venoms: neutralization by Mimosa pudica root extract. Fitoterapia. 2004; 75 3-4:378-80.
69.    Soares AM, Ticli FK, Marcussi S, Lourenço MV, Januario AH, Sampaio SV, Giglio JR, Lomonte B, Pereira PS. Medicinal plants with inhibitory properties against snake venoms. Current Medicinal Chemistry.1; 12(22):2625-41.
70.    Serova LI, Laukova M, Alaluf LG, Sabban EL. Intranasal infusion of melanocortin receptor four (MC4R) antagonist to rats ameliorates development of depression and anxiety related symptoms induced by single prolonged stress. Behavioural brain research. 2013; 1; 250:139-47.
71.    Sajid I, Bijan K, Zamiul R, Mominul I, Ekramul H. CNS Depressant and Antinociceptive Activities of the Aerial Parts of Mimosa pudica. Indian Journal Pharmaceutical Science; 2013; 5:127-33.
72.    Hossain M, Sultana S, Pharmacy. In-vivo Assessment of Neuropharmacological Activity of Methanol Bark Extract of Mimosa pudica in Mice. Advance in Pharmacology and Pharmacy. 2019; 7 2
73.    Adeyemi OO, Akindele AJ, Yemitan OK, Aigbe FR, Fagbo FI. Anticonvulsant, anxiolytic and sedative activities of the aqueous root extract of Securidaca longepedunculata Fresen. Journal of ethnopharmacology. 2010; 20; 130(2):191-5.
74.    Balsaraf SV, Chole RH. Antibacterial efficacy of Mimosa Pudica (Lajavanti) against streptococcus mutans. Journal of Indian Association of Public Health Dentistry. 2014; 1; 12(4):317.
75.    Sandeep DS, Narayana Charyulu R, Prashant Nayak, Aliss Maharjan, Indira Ghalan. Formulations of Antimicrobial Polyherbal Hand wash. Research J. Pharm. and Tech. 2016; 9(7):864-866.
76.    Rajalakshmi. K, N. Banu. Evaluation of Antibacterial Activity of Sodium Copper Chlorophyll in from Mimosa pudica L. Research J. Pharm. and Tech. 2017; 10(2): 487-489.
77.    Jainey P. James, Sneh Priya, Divya Jyothi. Effect of PLGA polymer on Antimicrobial Activity and the Release Studies of Nanoparticle Hydrogel Containing Mimosa pudica Extract. Research J. Pharm. and Tech 2018; 11(7): 2876-2880.
78.    Akter A, Neela F, Khan M, Islam M, Alam M. Screening of ethanol, petroleum ether and chloroform extracts of medicinal plants, Lawsonia inermis L. and Mimosa pudica L. for antibacterial activity. Indian journal of pharmaceutical science. 2010; 72 3 :388.
79.    Sreenivasulu V, Kumar NS, Suguna M, Asif M, Al-Ghurabi EH, Huang ZX, Zhen Z. Biosynthesis of silver nanoparticles using Mimosa pudica plant root extract: characterization, antibacterial activity and electrochemical detection of dopamine. International journal of electrochemistry and science. 2016 Dec 1; 11:9959-71.
80.    Tomar RS, Shrivastava V, Kaushik S. In vitro efficacy of methanolic extract of Mimosa pudica against selected micro-organisms for its broad spectrum antimicrobial activity. International Journal of Current Microbiology and Applied Sciences. 2014; 3(4):780-4.
81.    Md. Omar Faruk, Dibyajyoti Saha, Srikanta Chowdhury, Swati Paul, Md. Golam Kabir. In vitro Antioxidant activity of Methanolic Aerial Part Extract of Mimosa pudica. Research J. Pharmacology and Pharmacodynamics.2012; 4(4): 202-205.
82.    Muhammad MT, Abdullahi K, Shehu K, Shinkafi SA. Antifungal activity of Mimosa pudica leaves extracts against fungal isolates from razor bumps in Sokoto Metropolis, Nigeria. Annals of Biological Sciences. 2015; 3(1):16-9.
83.    Robinson RD, Williams LA, Lindo JF, Terry SI, Mansingh A. Inactivation of strongyloides stercoralis filariform larvae in vitro by six Jamaican plant extracts and three commercial anthelmintics. The West Indian Medical Journal. 1990; 1; 39(4):213-7.
84.    Malayan J, Selvaraj B, Warrier A, Shanmugam S, Mathayan M, Menon T. Anti-mumps virus activity by extracts of Mimosa pudica, a unique Indian medicinal plant. Indian journal of Virology 2013; 24(2):166-73.
85.    Jaya V, Ibrahim H, Othman L. Activities of Selected Plants against Hepatitis B Immunological Marker HBsAg. Malaysian Journal of Science. 2004; 26; 23(2):127-33.
86.    Nazeema T, Brindha V. Antihepatotoxic and antioxidant defense potential of Mimosa pudica. International Journal of drug discovery. 2009; 1:1-4.
87.    P. Muthukumaran, P. Shanmuganathan , C. Malathi. In Vitro Antioxidant Evaluation of Mimosa pudica. Asian J. Pharm. Res. 1(2): April-June 2011; Page 44-46.
88.    Zhang J, Yuan K, Zhou W-l, Zhou J, Yang P. Studies on the active components and antioxidant activities of the extracts of Mimosa pudica (Linn.) from southern China.Pharmacognosy magazine .2011; 25(7) :35.
89.    Arokiyaraj S, Sripriya N, Bhagya R, Radhika B, Prameela L, Udayaprakash NK. Phytochemical screening, antibacterial and free radical scavenging effects of Artemisia nilagirica, Mimosa pudica and Clerodendrum siphonanthus–An in–vitro study. Asian Pacific Journal of Tropical Biomedicine. 2012;1;2(2):S601-4.
90.    Ahmed S, Hasan MM, Mahmood ZA. Antiurolithiatic plants of family Fabaceae: A memoir of mechanism of action, therapeutic spectrum, formulations with doses. Journal of Pharmacognosy and Phytochemistry. 2017; 6(3):592-6.
91.    Lakshmi T, Devaraj E. Antiurolithiatic activity of phytochemical extracts: A review. Journal of Advanced Pharmacy Education & Research.2017; 7(3).
92.    KVSRG P, Sujatha D, Bharathi K. Herbal drugs in urolithiasis-a review. Pharmacog Rev. 2007 Jan; 1(1):175-8.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Recent Articles


Not Available