Author(s): Laith Muslih Najeeb, Safaa Abed Latef Al Meani, Ali Hazim Abdulkareem, Zyad Hameed Fyadh, Mohammed Mukhles Ahmed

Email(s): moh.mukhles@uoanbar.edu.iq

DOI: 10.52711/0974-360X.2022.00706   

Address: Laith Muslih Najeeb1, Safaa Abed Latef Al Meani2, Ali Hazim Abdulkareem3, Zyad Hameed Fyadh4, Mohammed Mukhles Ahmed5
1Department of Biology, College of Science, University of Anbar, Anbar, Iraq.
2,3,5Department of Biotechnology, College of Science, University of Anbar, Anbar, Iraq.
4Iraqi Ministry of Health - Anbar Health Department.
*Corresponding Author

Published In:   Volume - 15,      Issue - 9,     Year - 2022


ABSTRACT:
In many hospitals around the world, antibiotic resistance has reached a crisis. Mainly, Staphylococcus aureus (MRSA), which is immune to methicillin, is swamped and many with Gram-negative multidrug-resistant (MDR). The occurrence of carbapenmases for the first time was considered a major problem because of several factors, such as: many plasmids carrying gene resistance elements take on other resistance elements, including QnrA (QnrA and QnrB) and aminoglycoside (rmtB) Resistance elements. For severe MRSA infections, good treatment options are available, death rates continue to be high. The condition is more complicated and disturbing for MDR Gram-negatives. In developing countries, there are few new agents who can profit from the situation in the coming decade . Although the meanings are muddled, some patients in intensive care are thought to die because of the lack of antibiotics effective against Pseudomonas aeruginosa and A. baumanni. If molecular resistance is to be overcome, additional understanding is needed urgently. We additionally need to install early warning systems to keep pace with new resistances.


Cite this article:
Laith Muslih Najeeb, Safaa Abed Latef Al Meani, Ali Hazim Abdulkareem, Zyad Hameed Fyadh, Mohammed Mukhles Ahmed. Study the Epidemiology of Antibiotics Resistance in Ramadi Hospitals of Iraq. Research Journal of Pharmacy and Technology. 2022; 15(9):4204-7. doi: 10.52711/0974-360X.2022.00706

Cite(Electronic):
Laith Muslih Najeeb, Safaa Abed Latef Al Meani, Ali Hazim Abdulkareem, Zyad Hameed Fyadh, Mohammed Mukhles Ahmed. Study the Epidemiology of Antibiotics Resistance in Ramadi Hospitals of Iraq. Research Journal of Pharmacy and Technology. 2022; 15(9):4204-7. doi: 10.52711/0974-360X.2022.00706   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-9-66


REFERENCES:
1.    Theuretzbacher, U. and Piddock, L. J. V. Non-traditional antibacterial therapeutic options and challenges. Cell Host Microbe. 2019 ; 26, 61–72 . https://doi.org/10.1016/j.chom.2019.06.004
2.    Abbas, H. A., Kadry, A. A., Shaker, G. H. and Goda, R. M. Resistance of Escherichia coli and Klebsiella pneumoniae isolated from different Sources to β-lactam Antibiotics. Res. J. Pharm. Technol. 2017 ; 10, 589–591 . DOI : 10.5958/0974-360X.2017.00116.0
3.    Tanzella, G., Motos, A., Battaglini, D., Meli, A. and Torres, A. Optimal approaches to preventing severe community-acquired pneumonia. Expert Rev. Respir. Med. 2019 ;13, 1005–1018 . https://doi.org/10.1080/17476348.2019.1656531
4.    Joel, J. J., Bhat, V. S. and ER, A. R. Study on drug utilization pattern of antibiotics in Respiratory Tract Infections. Res. J. Pharm. Technol. 2019 ; 12, 1189–1192 . DOI: 10.5958/0974-360X.2019.00197.5
5.    Duong, M. T.-Q., Qin, Y., You, S.-H. and Min, J.-J. Bacteria-cancer interactions: bacteria-based cancer therapy. Exp. Mol. Med. 2019 ; 51, 1–15 . DOI: 10.1038/s12276-019-0297-0
6.    Lokhasudhan, G. and Ajitha, P. Role of Antibiotics as Intracanal Medicament-A Literature Review. Res. J. Pharm. Technol. 2018 ; 11, 1691–1696 . DOI : 10.5958/0974-360X.2018.00315.3
7.    Ramalingam, A. J. History of antibiotics and evolution of resistance. Res. J. Pharm. Technol 2015; 8, 1719–1724 . DOI : 10.5958/0974-360X.2015.00309.1
8.    Swan, T. A. Exploring wellness programming awareness, usage, and perceived leadership support among community college employees. 2020 ;. https://hdl.handle.net/11274/12615
9.    Ahmed, M. M. and Al Meani, S. A. L. Occurrence of Klebsiella pneumoniae carbapenemase KPC gene in Klebsiella pneumoniaeisolated from patients in Anbar city of Iraq. Ann. Trop. Med. Public Heal. 2019 ; 22, . DOI: http://doi.org/10.36295/ASRO.2019.220514
10.    Jain, M. S. and Barhate, S. D. Tigecycline is the First Clinically-Available Drug in a new class of Antibiotics called the Glycylcyclines: A Review. Asian J. Pharm. Technol. 2020 ; 10, 48–50. DOI : 10.5958/2231-5713.2020.00010.0
11.    Ibrahim, M. O. and Al Meani, S. A. L. detection of plasmid-mediated Ampc β-lactamase genes and evaluation the synergistic effect of clove volatile oil and antibiotics in clinical isolates of Klebsiella pneumonia in iraq. DOI : 10.35124/bca.2019.19.2.4053
12.    Eveillard, M., Kempf, M., Belmonte, O., Pailhoriès, H. and Joly-Guillou, M.-L. Reservoirs of Acinetobacter baumannii outside the hospital and potential involvement in emerging human community-acquired infections. Int. J. Infect. Dis. 2013 ; 17, e802–e805 . https://doi.org/10.1016/j.ijid.2013.03.021
13.    Abozed, M. F., Abd El Latif, H. K., Serry, F. M. and El Sayed, L. M. Activity of commonly used intravenous nutrient and bisolvon in neonatal intensive care units against biofilm cells and their synergetic effect with antibiotics. Asian J. Pharm. Technol. 2013 ; 3, 81–90. https://doi.org/10.5301/ijao.5000135
14.    Singh, H., Kaur, R. and Singh, S. Use of Syzgium aromaticum (Clove) in combination with standard antibiotics: Application in antimicrobial chemotherapy. Res. J. Pharm. Technol. 2018 ; 11, 1815–1819 . DOI : 10.5958/0974-360X.2018.00337.2
15.    Thyagarajaan, R., Namasivayam, S. K. R., Narendrakumar, G., Singh, V. and Samydurai, S. Evaluation of in Vitro Drug Controlled Release of Biocompatible Metallic and Non Metallic Nanoparticles Incorporated Anti Bacterial Antibiotics and Their Anti Biofilm Activity Against E. coli. Res. J. Pharm. Technol. 2015; 8, 316 . DOI : 10.5958/0974-360X.2015.00052.9
16.    Ahmed, A. M. M. and Al Meani, S. L. Occurrence of Klebsiella pneumoniae carbapenemase KPC gene in Klebsiella pneumoniaeisolated from patients in Anbar city of Iraq. Ann. Trop. Med. Heal. 2019;22, 108–116. DOI: http://doi.org/10.36295/ASRO.2019.220514
17.    Rupashri, S. V and Karpagavalli, S. Benefits of Prophylactic Antibiotics in Third Molar Impaction. Res. J. Pharm. Technol. 2015 ; 8, 1028–1032 . DOI : 10.5958/0974-360X.2015.00175.4
18.    Hameed, A. M. and Najeeb, L. M. Molecular Detection of blaOXA-51 in Carbapenem-resistant Acinetobacterbaumannii Isolated from Different Clinical Sources. Med. Leg. Updat. 2020; 20, 693–696 . https://doi.org/10.1186/s13756-019-0611-6
19.    Gayathri, A., Madhanraj, P. and Panneerselvam, A. Diversity, Antibacterial Activity And Molecular Characterization of Actinomycetes Isolated From Salt Pan Region of Kodiakarai, Nagapattinam DT. Asian J. Pharm. Technol. 2011;1, 79–81 . DOI: 10.5958/0974-360X.2020.00545.4
20.    Ragheb, Y. M. and Abdulkarim, A. H. Phenotypic and Genotypic Detection Ampc β-Lactmase Producing E. coli Isolated from UTI in Anbar Governate. Ann. Rom. Soc. Cell Biol. 2021;1181–1192 . https://doi.org/10.1155/2020/8042540
21.    Hemalatha, K., Raj, D. N., Begam, M. F., Sharanya, V. K. and Girija, K. Synthesis, Characterization, Docking study and Anti-Bacterial Evaluation of Benzimidazole Derivatives as Biotin Carboxylase Inhibitors. Asian J. Pharm. Technol. 2017;7, 109–114 . DOI : 10.5958/2231-5713.2017.00019.8
22.    Ahmed, S. H. and Shehan, M. A. Phenotypic and Genotypic Detection of Extended Spectrum β-lactamase in MDR-Klebsiella pneumoniae in Anbar Governate. Ann. Rom. Soc. Cell Biol. 2021; 4984–4992 . https://www.annalsofrscb.ro/index.php/journal/article/view/3051
23.    Kale, D. R., Khedkar, A. N. and Pawar, J. B. Formulation and in-vitro Evaluation of floating tablets of Antibiotics used in the treatment of Peptic ulcer. Asian J. Pharm. Technol. 2021; 11, DOI : 10.5958/2231-5713.2021.00004.0
24.    Sun, J. et al. Prolonged persistence of SARS-CoV-2 RNA in body fluids. Emerg. Infect. Dis. 2020 ;26, 1834 . doi: 10.3201/eid2608.201097
25.    Patil, S. D. et al. Evaluation Ixora coccinea Formulation for antibacterial and antioxidant activity. Asian J. Pharm. Technol. 2018 ; 8, 88–91 . DOI : 10.5958/2231-5713.2018.00014.4
26.    Spellberg, B. and Gilbert, D. N. The future of antibiotics and resistance: a tribute to a career of leadership by John Bartlett. Clin. Infect. Dis. 2014;59, S71–S75. https://doi.org/10.1093/cid/ciu392
27.    Malathi, R., Cholarajan, A., Karpagam, K., Jaya, K. R. and Muthukumaran, P. Antimicrobial studies on selected medicinal plants (Coleus amboinicus, Phyla nodiflora and Vitex negundo). Asian J. Pharm. Technol. 2011;1, 53–55. DOI: http://dx.doi.org/10.20902/IJCTR.2011.110821
28.    Lowy, F. D. Antimicrobial resistance: the example of Staphylococcus aureus. J. Clin. Invest. 2003 ; 111, 1265–1273 . https://doi.org/10.1172/JCI18535.
29.    Chopra, I. and Roberts, M. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. Microbiol. Mol. Biol. Rev. 2001; 65, 232–260 . DOI:https://doi.org/10.1128/MMBR.65.2.232-260.2001
30.    Abuskhuna, S. M., Zeglam, T. H., Fhid, O. N. R. and Jebril, A. O. Antibacterial Activity of Hydroxyimidazole Derivatives. Asian J. Pharm. Technol. 2020;10, 7–10 . DOI : 10.5958/2231-5713.2020.00002.1
31.    Kumar, R. and Pundir, S. Bacterial cell, classification and required essential contents for growth. Asian J. Pharm. Technol. 2021;11, 181–187 . DOI: 10.52711/2231-5713.2021.00030

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