Rasmita Jena, Diptirani Rath, Monalisa Rout, Sovan Pattanaik, Durga Madhab Kar
Rasmita Jena1,2, Diptirani Rath1, Monalisa Rout1, Sovan Pattanaik1, Durga Madhab Kar1*
1Department of Pharmacology, School of Pharmaceutical Sciences, Siksha ‘O’ Anusandhan Deemed to be University, Bhubaneswar -751003, Odisha, India.
2School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Odisha, India.
Volume - 15,
Issue - 8,
Year - 2022
Bacopa monnieri and Convolvulus pluricaulis with the Panchagavya ghrita are expected to have better nootropic activity than the combination of Bacopa monnieri and Convolvulus pluricaulis. These marshy herbs are found throughout India having various medicinal importances like treatment of ulcer, epilepsy, memory improvement. The present study was focused on the exploration and assessment of memory and learning activity from the aqueous and methanol extract of Bacopa monnieri (Brahmi) and Convolvulus pluricaulis (Sankhapuspi) leaves with and without the Panchagavya ghrita (PGG) by performing different pharmacological screening models. The study of nootropic activity was performed by using different screening methods such as; phenobarbitone sodium-induced sleeping time, elevated plus maze, radial arm maze, actophotometer. Both methanol and aqueous extracts of Brahmi, Sankhapuspi with the combinations of Panchagavya ghrita showed a significant increase in memory and learning activity as compared to solvent control group where methanol extract containing combination exhibited better enhancement of memory learning activity in all experimental models as compared to aqueous extract. However, it is confirmed that herbs are having excellent activities in learning and memory when combined with Panchagavya ghrita.
Cite this article:
Rasmita Jena, Diptirani Rath, Monalisa Rout, Sovan Pattanaik, Durga Madhab Kar. Evaluation of Nootropic activity of Bacopa monnieri and Convolvulus pluricaulis herbs extracts with Panchagavya ghrita. Research Journal of Pharmacy and Technology. 2022; 15(8):3365-9. doi: 10.52711/0974-360X.2022.00563
Rasmita Jena, Diptirani Rath, Monalisa Rout, Sovan Pattanaik, Durga Madhab Kar. Evaluation of Nootropic activity of Bacopa monnieri and Convolvulus pluricaulis herbs extracts with Panchagavya ghrita. Research Journal of Pharmacy and Technology. 2022; 15(8):3365-9. doi: 10.52711/0974-360X.2022.00563 Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-8-5
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