Author(s): Rakesh N. Chaudhari, Amit Kumar Jain, Vivekanand K. Chatap


DOI: 10.52711/0974-360X.2022.00389   

Address: Rakesh N. Chaudhari1*, Amit Kumar Jain2, Vivekanand K. Chatap3
1Research Scholar, Faculty of Pharmacy, B.R. Nahata College of Pharmacy, Mandsaur University, Mandsaur, MP – 458001.
2Professor, Faculty of Pharmacy, B.R. Nahata College of Pharmacy, Mandsaur University, Mandsaur, MP – 458001.
3Assistant Professor, H.R. Patel Institute of Pharmaceutical Education and Research, Shirpur, Tal. Shirpur, Dist. Dhule.
*Corresponding Author

Published In:   Volume - 15,      Issue - 5,     Year - 2022

The importance of medicinal plants and traditional health systems in solving the world's health-care problems is increasingly being focused. Worldwide maximum population has a belief in natural resources (i.e. plants) for disease treatment, either due to diseases of drug resistance or synthetic drug side effects. To plant products in current research lines of phytochemical analysis, pharmacological screening and clinical trials, ethano-medicinal studies have thus been recognised in recent years. This analysis offers details about the botanical definition, common uses, phytochemistry and pharmacology of Pyrostegia venusta, one such essential herb. Pyrostegia venusta (Ker Gawl.) Miers, a native of the Brazilian Cerrado and popularly known as "cipó-de-são-joão," Bignoniaceae. In Brazilian herbal medicine, the flowers of P. venusta are used as a general tonic and a treatment for diarrhea, vitiligo, cough, and common illnesses and inflammatory disorders of the respiratory system. The current review could provide a sound basis for further research into the potential discovery of new natural bioactive compounds, and could provide preliminary information for future research.

Cite this article:
Rakesh N. Chaudhari, Amit Kumar Jain, Vivekanand K. Chatap. An Overview on Phyto-chemistry, Traditional and Pharmacological aspects of Pyrostegia Venusta. Research Journal of Pharmacy and Technology. 2022; 15(5):2339-5. doi: 10.52711/0974-360X.2022.00389

Rakesh N. Chaudhari, Amit Kumar Jain, Vivekanand K. Chatap. An Overview on Phyto-chemistry, Traditional and Pharmacological aspects of Pyrostegia Venusta. Research Journal of Pharmacy and Technology. 2022; 15(5):2339-5. doi: 10.52711/0974-360X.2022.00389   Available on:

1.    Dar RA, Shahnawaz M, Qazi PH. General overview of medicinal plants: a review. J Phytopharmacol. 2017;6(6):349-51.
2.    Li TS. Medicinal plants: culture, utilization and phytopharmacology. CRC press; 2000.
3.    Hamburger M, Hostettmann K. 7. Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry. 1991;30(12):3864-74. doi: 10.1016/0031-9422(91)83425-K.
4.    Dey YN, Ota S, Srikanth N, Jamal M, Wanjari M. A phytopharmacological review on an important medicinal plant-Amorphophallus paeoniifolius. Ayu. 2012;33(1):27-32. doi: 10.4103/0974-8520.100303, PMID 23049180.
5.    Ferreira DT, Alvares PSM, Houghton PJ, Braz-Filho R. Chemical constituents from roots of Pyrostegia venusta and considerations about its medicinal importance. Quim Nova. 2000;23(1):42-6. doi: 10.1590/S0100-40422000000100010.
6.    Scalon S, Vieira M, Lima A, Souza C, Mussury R. Pregerminative treatments and incubation temperatures on the germination of Cipó-de-são-joão"[Pyrostegia venusta (Ker Gawl.) Miers]-Bignoniaceae. Rev Bras Plant Med. 2008;10:37-42.
7.    Veloso CC, Bitencourt AD, Cabral LD, Franqui LS, Dias DF, dos Santos MH, Soncini R, Giusti-Paiva A. Pyrostegia venusta attenuate the sickness behavior induced by lipopolysaccharide in mice. J Ethnopharmacol. 2010;132(1):355-8. doi: 10.1016/j.jep.2010.07.053, PMID 20727400.
8.    Singh S, Rana A, Chauhan SV. Impact of environmental changes on the reproductive biology in Pyrostegia venusta Presl. J Environ Biol. 2009;30(2):271-3. PMID 20121030.
9.    Ndayisenga I. Pyrostegia venusta ker Gwal Miers [thesis]: Butare city ornamental plant taxonomy and phytogeography; submitted.
10.    Dubey R. Chemical components of Pyrostegia venusta flowers; 1976.
11.    Harborne JB. Comparative biochemistry of the flavonoids-VI. Phytochemistry. 1967;6(12):1643-51. doi: 10.1016/S0031-9422(00)82897-6.
12.    Blatt CTT, dos Santos MD, Salatino A. Flavonoids ofBignoniaceae from the ”cerrado” and their possible taxonomic significance. Plant Syst Evol. 1998;210(3-4):289-92. doi: 10.1007/BF00985673.
13.    Roy P, Amdekar S, Kumar A, Singh V. Preliminary study of the antioxidant properties of flowers and roots of Pyrostegia venusta (Ker Gawl) Miers. BMC Complement Altern Med. 2011;11(1):69. doi: 10.1186/1472-6882-11-69, PMID 21861910.
14.    Gupta MB, Nath R, Srivastava N, Shanker K, Kishor K, Bhargava KP. Anti-inflammatory and antipyretic activities of β-sitosterol. Planta Med. 1980;39(2):157-63. doi: 10.1055/s-2008-1074919, PMID 6967611.
15.    Shen KH, Hung SH, Yin LT, Huang CS, Chao CH, Liu CL, Shih YW. Acacetin, a flavonoid, inhibits the invasion and migration of human prostate cancer DU145 cells via inactivation of the p38 MAPK signaling pathway. Mol Cell Biochem. 2010;333(1-2):279-91. doi: 10.1007/s11010-009-0229-8, PMID 19693651.
16.    Mostafa N, El-Dahshan O, Singab A. Pyrostegia venusta (Ker Gawl.) Miers: a botanical, pharmacological and phytochemical review. Med Aromat Plants. 2013;2(3):1-6.
17.    Altoé TD, de Amorim GM, Gomes JVD, Borges AS, Valadão IC, Silva IV, et al. In vitro antioxidant and cell viability of Pyrostegia venusta (Ker Gawl.) Miers. Orbital Electron J Chem. 2014;6(4):215-22.
18.    Mo Z, Wang X, Zhang X, Su J, Chen H, Liu Y, Zhang Z, Xie J, Su Z. Andrographolide sodium bisulphite-induced inactivation of urease: inhibitory potency, kinetics and mechanism. BMC Complement Altern Med. 2015;15(1):238. doi: 10.1186/s12906-015-0775-4.
19.    Serra CP, Côrtes SdF, Lombardi JA, Braga de Oliveira AB, Braga FC. Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts. Phytomedicine. 2005;12(6-7):424-32. doi: 10.1016/j.phymed.2004.07.002, PMID 16008118.
20.    Magalhaes EA, Silva J, de Campos TA, Silva LP, Silva RM. The evaluation of the genotoxic potency of the Pyrostegia venusta (Ker Gawl.) Miers, Bignoneaceae, crude extract on bone marrow of mice. Rev Bras Farmacognosia. 2010;20(1):65-9.
21.    Moreira CG, Horinouchi CD, Souza-Filho CS, Campos FR, Barison A, Cabrini DA, Otuki MF. Hyperpigmentant activity of leaves and flowers extracts of Pyrostegia venusta on murine B16F10 melanoma. J Ethnopharmacol. 2012;141(3):1005-11. doi: 10.1016/j.jep.2012.03.047, PMID 22504061.
22.    Moreira CG, Carrenho LZ, Pawloski PL, Soley BS, Cabrini DA, Otuki MF. Pre-clinical evidences of Pyrostegia venusta in the treatment of vitiligo. J Ethnopharmacol. 2015;168:315-25. doi: 10.1016/j.jep.2015.03.080, PMID 25862965.
23.    De Sousa MB, Júnior JOCS, Barbosa WLR, da Silva Valério E, da Mata Lima A, de Araújo MH, Muzitano MF, Nakamura CV, de Mello JC, Teixeira FM. Pyrostegia venusta (Ker Gawl.) miers crude extract and fractions: prevention of dental biofilm formation and immunomodulatory capacity. Pharmacogn Mag. 2016;12(Suppl 2);Suppl 2:S218-22. doi: 10.4103/0973-1296.182150, PMID 27279710.
24.    Nisha P, Shruti N, Sweta Swamy K, Meera Kumari VA, Krishna V, Joy HH. Anthelmintic activity of Pyrostegia venusta using Pheretima posthuma. Int J Pharm Sci Drug Res. 2012;4(3):205-8.
25.    Figueiredo CR, Matsuo AL, Pereira FV, Rabaça AN, Farias CF, Girola N, Massaoka MH, Azevedo RA, Scutti JA, Arruda DC, Silva LP, Rodrigues EG, Lago JH, Travassos LR, Silva RM. Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo. Pharmacogn Mag. 2014;10(Suppl 2);Suppl 2:S363-76. doi: 10.4103/0973-1296.133284, PMID 24991116.
26.    Pereira A, Hernandes C, Pereira S, Bertoni B, França S, Pereira P, Taleb-Contini S. Anticandidal and antioxidant activities of fractions and isolated compounds of Pyrostegia venusta (Ker Gawl.) Miers. Planta Med. 2013;79(5):7. doi: 10.1055/s-0033-1336449.
27.    Veloso CC, Cabral LDM, Bitencourt AD, Franqui LS, Santa-Cecília FV, Dias DF, Soncini R, Vilela FC, Giusti-Paiva A. Anti-inflammatory and antinociceptive effects of the hydroethanolic extract of the flowers of Pyrostegia venusta in mice. Rev Bras Farmacognosia. 2012;22(1):162-8. doi: 10.1590/S0102-695X2011005000209.
28.    Pan MH, Lai CS, Wang YJ, Ho CT. Acacetin suppressed LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice. Biochem Pharmacol. 2006;72(10):1293-303. doi: 10.1016/j.bcp.2006.07.039, PMID 16949556.
29.    Pan MH, Hsieh MC, Hsu PC, Ho SY, Lai CS, Wu H, Sang S, Ho CT. 6‐Shogaol suppressed lipopolysaccharide‐induced up‐expression of iNOS and COX‐2 in murine macrophages. Mol Nutr Food Res. 2008;52(12):1467-77. doi: 10.1002/mnfr.200700515, PMID 18683823.
30.    Cytokine DR. sickness behavior, and depression. Immunology and Allergy Clinics. 2009;29(2):247-64.
31.    De Paiva VN, Lima SN, Fernandes MM, Soncini R, Andrade CA, Giusti-Paiva A. Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice. Behav Brain Res. 2010;215(1):146-51. doi: 10.1016/j.bbr.2010.07.015, PMID 20654654.
32.    Usman MRM, Chaubey N. Anti-inflammatory and analgesic Activities of Pyrostegia venusta pres. stems. Int J Pharm Sci Res. 2018;9(11):4696-700.
33.    Kumar A, Asthana M, Roy P, Amdekar S, Singh V. Phytochemistry and pharmacology of Pyrostegia venusta: a plant of family Bignoniaceae. Int J Phytomed. 2013;5(3):257.
34.    Lima LA, Siani AC, Brito FA, Sampaio ALF, Henriques MdGMO, Riehl CAdS. Correlation of anti-inflammatory activity with phenolic content in the leaves of Syzygium cumini (L.) Skeels (Myrtaceae). Quim Nova. 2007;30(4):860-4. doi: 10.1590/S0100-40422007000400019.
35.    Mertz PM, Ovington LG. Wound healing microbiology. Dermatol Clin. 1993;11(4):739-47. doi: 10.1016/S0733-8635(18)30226-2, PMID 8222357.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

56th percentile
Powered by  Scopus

SCImago Journal & Country Rank

Recent Articles


Not Available