Author(s): Ibrahim Alfarrayeh, Khaled Tarawneh, Dima Almajali, Wajdy Al-Awaida

Email(s): alfarrayeh@gmail.com , khaled_tarawneh@hotmail.com , w.alawaida@aum.edu.jo , demamajali@gmail.com

DOI: 10.52711/0974-360X.2022.00350   

Address: Ibrahim Alfarrayeh1*, Khaled Tarawneh1, Dima Almajali1, Wajdy Al-Awaida2
1Department of Biological Sciences, Faculty of Sciences, Mu'tah University, Al-Karak, Jordan.
2Department of Biology and Biotechnology, American University of Madaba, Madaba, Jordan.
*Corresponding Author

Published In:   Volume - 15,      Issue - 5,     Year - 2022


ABSTRACT:
In this study, the methanolic extracts from four medicinal plants (Sarcopoterium spinosum, Paronychia argentea, Inula viscosa, and Achillea fragrantissima) were tested in vitro for antibacterial and antioxidant properties. The antibacterial properties of these MPEs were assessed using disc diffusion and Serial dilution techniques. The antioxidant properties were evaluated by DPPH and FRAP methods. The total phenolic compounds were measured according to Folin-Ciocalteu method. Differences were found among the tested plants in their antibacterial and antioxidant properties as well as the phenolic content. Among the four plants, I. viscosa revealed the highest antibacterial effects against all bacterial species under examination followed by S. spinosum. Gram-positive bacteria showed higher susceptibility to the MPEs than Gram-negative bacteria. Antioxidant capacity and polyphenolic content investigations revealed that S. spinosum and I. viscosa have the highest antioxidant activities and the highest amount of phenolic compounds. Moreover, a strong positive linear correlation was found between antioxidant activity and total phenolic content. In conclusion, the MPEs of I. viscosa and S. spinosum have been proven to have good antibacterial and antioxidant activities which were highly related to their contents of phenolic compounds. These plant extracts could be interesting sources for natural antibacterial and antioxidant agents.


Cite this article:
Ibrahim Alfarrayeh, Khaled Tarawneh, Dima Almajali, Wajdy Al-Awaida. Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents. Research Journal of Pharmacy and Technology. 2022; 15(5):2110-6. doi: 10.52711/0974-360X.2022.00350

Cite(Electronic):
Ibrahim Alfarrayeh, Khaled Tarawneh, Dima Almajali, Wajdy Al-Awaida. Evaluation of the Antibacterial and Antioxidant properties of the Methanolic extracts of four Medicinal plants selected from Wadi Al-Karak, Jordan related to their Phenolic contents. Research Journal of Pharmacy and Technology. 2022; 15(5):2110-6. doi: 10.52711/0974-360X.2022.00350   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-5-32


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