Author(s): Dileep Singh Baghel, Saurabh Singh, Narendra Kumar Pandey, Bimlesh Kumar, Amit Mittal, Anand Kumar Chaudhary, Anu Mittal, Amrik Singh

Email(s): bimlesh.12474@lpu.co.in , dileep.15210@lpu.co.in , amit.13145@lpu.co.in

DOI: 10.52711/0974-360X.2022.00334   

Address: Dileep Singh Baghel1, Saurabh Singh1, Narendra Kumar Pandey1, Bimlesh Kumar1, Amit Mittal1*, Anand Kumar Chaudhary2, Anu Mittal3, Amrik Singh4
1School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India.
2Department of Rasa Shastra and Bhaishjya Kalpana (Ayurvedic Pharmaceutics), Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Uttar Pradesh, India.
3Department of Chemistry, Guru Nanak Dev University Collage, Patti, Tran Taran, Punjab, India.
4School of Hotel Management and Tourism, Lovely Professional University, Punjab, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 5,     Year - 2022


ABSTRACT:
Background: Urolithiasis (Mutrakricchra) is an age-old disorder which has multi-factorial etiological as well as associated with re-occurrence. It is standout among the most troubling disorders related to urinary tract. Acharya Sushruta, a pioneer in the art of surgery, described the root causes and management of urolithiasis (Mutrakricchra). In present day restorative practice, a lot of the management/treatment choices are available which begins from the utilization of uresis-elevating specialist to dietary or nourishing enhancement consumption. Amalgamating the Ayurvedic principle/concept with current medicinal practice is a promising methodology used for the management of urolithiasis (Mutrakricchra) now a days. Objective: To prepare apamarg kshar and evaluate its potential against Urolithiasis (Mutrakrichra) by In-vitro technique. Materials and Methods: Apamarg kshar were prepared as per the methodology mentioned in Rasatarangni and the prepared Kshar is compressed in tablet dosage form. Various parameters of apmarg kshar tablets were evaluated. Results: Physicochemical and stability studies have not shown any remarkable variations with prepared tablet dosage form. In-vitro studies shows that 82 % of crystal inhibition at 550 µg/ml. Conclusion: The prepared tablet dosage form of Apamarg Kshar does not have remarkable variation during physicochemical and stability studies. The developed dosage form produces promising result in vitro against Urolithiasis (Mutrakrichra).


Cite this article:
Dileep Singh Baghel, Saurabh Singh, Narendra Kumar Pandey, Bimlesh Kumar, Amit Mittal, Anand Kumar Chaudhary, Anu Mittal, Amrik Singh. Preparation of Apamarg Kshar Tablet and Assessment of In Vitro Potential against Urolithiasis (Mutrakrichra). Research Journal of Pharmacy and Technology. 2022; 15(5):2017-7. doi: 10.52711/0974-360X.2022.00334

Cite(Electronic):
Dileep Singh Baghel, Saurabh Singh, Narendra Kumar Pandey, Bimlesh Kumar, Amit Mittal, Anand Kumar Chaudhary, Anu Mittal, Amrik Singh. Preparation of Apamarg Kshar Tablet and Assessment of In Vitro Potential against Urolithiasis (Mutrakrichra). Research Journal of Pharmacy and Technology. 2022; 15(5):2017-7. doi: 10.52711/0974-360X.2022.00334   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-5-16


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