Author(s): Riya Jalan, Biswaranjan Pradhan, Santosh Kumar Singh, Anuradha Das, Rajib Lochan Barik, Jyotisikha Meher, Rashmi Ranjan Mishra, Debasmita Dubey, Bikash Chandra Behera

Email(s): bikashnou@gmail.com

DOI: 10.52711/0974-360X.2022.00242   

Address: Riya Jalan1, Biswaranjan Pradhan2, Santosh Kumar Singh3, Anuradha Das4, Rajib Lochan Barik5, Jyotisikha Meher1, Rashmi Ranjan Mishra1, Debasmita Dubey6, Bikash Chandra Behera1*
1Department of Biotechnology, MITS School of Biotechnology, Odisha - 751024, India.
2S.K. Dash Centre of Excellence of Biosciences and Engineering and Technology, Indian Institute of Technology, Bhubaneswar - 752050, India.
3Department of Biotechnology, School of Health and Allied Sciences, Arka Jain University, Jamshedpur – 831001, India.
4School of Chemical Sciences, National Institute of Science Education and Research, Bhubaneswar - 752050, India.
5District Public Health Laboratory, District Head Quarters Hospital, Baripada - 757001, India.
6Medical Research Laboratory, IMS and SUM Hospital, Siksha ‘O’Anusandhan Deemed to be University, Bhubaneswar - 751003, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 4,     Year - 2022


ABSTRACT:
Nine actinobacteria were isolated from the mangrove soil of Bhitarkanika and screened for their bioactive metabolites and antimicrobial property. Out of the nine actinobacterial isolates, the bacterial isolate BAB-7 showed positive activity towards most of the enzymes screened, i.e., cellulase, phosphate solubilization, L-asparaginase, protease, and amylase. The actinobacterial isolate BAB-7 also exhibited antimicrobial activity against K. pneumoniae, V. alginolyticus, V. parahaemolyticus, P. aeruginosa, E. coli, S. typhimurium, and S. salivarius. Based on biochemical characterization, the actinobacterial isolate BAB-7 was identified as Steptomyces sp. The secondary metabolites produced by the bacterial strain were analyzed through GC-mass spectroscopy and found to be similar to the peaks of 2-cyclohex-3-en-1-yl-2-oxoacetic acid derivative (ketomycin).


Cite this article:
Riya Jalan, Biswaranjan Pradhan, Santosh Kumar Singh, Anuradha Das, Rajib Lochan Barik, Jyotisikha Meher, Rashmi Ranjan Mishra, Debasmita Dubey, Bikash Chandra Behera. Isolation and Identification of Antibacterial compound from Actinomycetes isolated from Mangrove soil. Research Journal of Pharmacy and Technology. 2022; 15(4):1461-6. doi: 10.52711/0974-360X.2022.00242

Cite(Electronic):
Riya Jalan, Biswaranjan Pradhan, Santosh Kumar Singh, Anuradha Das, Rajib Lochan Barik, Jyotisikha Meher, Rashmi Ranjan Mishra, Debasmita Dubey, Bikash Chandra Behera. Isolation and Identification of Antibacterial compound from Actinomycetes isolated from Mangrove soil. Research Journal of Pharmacy and Technology. 2022; 15(4):1461-6. doi: 10.52711/0974-360X.2022.00242   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-4-8


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