Author(s):
A. Shukla, P. Pokhriyal
Email(s):
abha.shukla@gkv.ac.in , priyanka123pokhriyal@gmail.com
DOI:
10.52711/0974-360X.2022.00290
Address:
A. Shukla, P. Pokhriyal*
Department of Chemistry, Kanya Gurukul Campus, Gurukul Kangri Vishwavidyalaya, Haridwar-249404, Uttrakhand, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 4,
Year - 2022
ABSTRACT:
Background: This study aimed to examine the anti-inflammatory and antidiabetic effects of the green solvent extract from F.subincisa Buch-Ham.ExSm.This paper also explains how bio-based products have been highly safe and alternative to the use of organic solvent. Methods: The serial extraction was carried out with increasing polarity using a magnetic stirrer: d-limonene, Isopropyl alcohol, Ethyl lactate, and Hydroalcohol.The concentrated and dried extracts were subjected to analysis the antidiabetic activity and anti-inflammatory activity were assessed by employing standard in vitro techniques. Result: In vitro anti-inflammatory assays were performed using heat-induced bovine serum albumin (BSA) denaturation and erythrocyte membrane stabilization assays.a-amylase and a-glucosidase were used to evaluate the anti-diabetic activity of F.subincisa bark in vitro. Diclofenac sodium, Acarbose, and aspirin were used as reference drugs. The in vitro method showed significant anti-inflammatory and anti-diabetic properties of different bio-based extracts tested. Conclusions: Findings from this study showed that F.subincisa exhibited substantial anti-inflammatory and antidiabetic actions in vitro models.
Cite this article:
A. Shukla, P. Pokhriyal. A desirability approach for Antidiabetic and Antiinflammatory efficacy of Ficus subincisa bark. Research Journal of Pharmacy and Technology. 2022; 15(4):1732-6. doi: 10.52711/0974-360X.2022.00290
Cite(Electronic):
A. Shukla, P. Pokhriyal. A desirability approach for Antidiabetic and Antiinflammatory efficacy of Ficus subincisa bark. Research Journal of Pharmacy and Technology. 2022; 15(4):1732-6. doi: 10.52711/0974-360X.2022.00290 Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-4-56
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