Author(s): Suma. S, Hari Prasad. V, Abeetha. S, Tejashwini. K, Renu Sharda

Email(s): msrenu01@gmail.com , dr.hariprasad86@gmail.com , subramanian.or.abee@gmail.com , teja16k@gmail.com , meena.30@hotmail.com

DOI: 10.52711/0974-360X.2022.00266   

Address: Suma. S1, Hari Prasad. V2, Abeetha. S3, Tejashwini. K4, Renu Sharda5
1Assistant Professor, Dept of Physiology, Saveetha Medical College and Hospital, Chennai, India.
2Associate Professor, Dept of Forensic Medicine, Panimalar Medical College Hospital and Research Institute, Chennai, India.
3Associate Professor, Dept of Physiology, ACS Medical College and Hospital, Chennai, India.
4Manager, Tata Consultancy Services ltd, Banglore, India.
5Senior Resident, Dept of Plastic Surgery, PGIMER, Chandigarh, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 4,     Year - 2022


ABSTRACT:
Background: Congenital deafness is usually seen to be associated with number of heart diseases. Screening congenitally deaf children with ECG can give us an insight on unidentified congenitally associated heart disease. Aim and objective: To study the ECG changes in congenitally deaf children and compare with normal children of the same age group. Materials and methods: We conducted a community based cross sectional analytical study with a sample size of 120 subjects out of which 60 were children from deaf school as cases and 60 were children from normal school with normal hearing as controls. Both the groups had 30 males and 30 females. 12 lead ECG was taken, studied and compared among the two groups. Results: Deaf children showed significant ECG changes like long QTc (16.7%), left axis deviation (3.3%), right axis deviation (1.6%), clockwise rotation (8.33%), anticlockwise rotation (5%), QRS complex abnormalities (45%), T wave inversions (45%). Conclusion: Our study was able to pick up numerous changes in ECG of deaf children. Yet the findings are inconclusive. Further genetic and thorough cardiac evaluation is necessary to comprehensively establish the relation between co-occurrence of ECG changes and congenital sensorineural deafness.


Cite this article:
Suma. S, Hari Prasad. V, Abeetha. S, Tejashwini. K, Renu Sharda. A Comparative study on ECG changes among normal and otherwise healthy congenitally deaf children. Research Journal of Pharmacy and Technology. 2022; 15(4):1594-7. doi: 10.52711/0974-360X.2022.00266

Cite(Electronic):
Suma. S, Hari Prasad. V, Abeetha. S, Tejashwini. K, Renu Sharda. A Comparative study on ECG changes among normal and otherwise healthy congenitally deaf children. Research Journal of Pharmacy and Technology. 2022; 15(4):1594-7. doi: 10.52711/0974-360X.2022.00266   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-4-32


REFERENCES:
1.    Rokicki W.  Markiewicz-Loskot G. Michalewska A.  Wludarczyk W.  Mizia M.  Preliminary cardiological examination in deaf children. Przegl Lek. 2002; 59(9): 737-739.
2.    Faridi R. Tona R. Brofferio A. Hoa M. Olszewski R. Schrauwen I. Assir MZK et al Mutational and phenotypic spectra of KCNE1 deficiency in Jervell and Lange-Nielsen Syndrome and Romano-Ward Syndrome. Hum Mutat. 2019. Feb;40(2):162-176. doi: 10.1002/humu.23689. Epub 2018 Dec 12. PMID: 30461122; PMCID: PMC6328321.
3.    Priori SG. Schwartz PJ. Napolitano C. Bloise R.  Ronchetti E. Grillo M et al Risk stratification in the long-QT syndrome. N Engl J Med. 2003; 348(19):1866-74. doi: 10.1056/NEJMoa022147. PMID: 12736279.
4.    Schwartz PJ.  Priori SG. Spazzolini C.  Moss AJ.  Vincent GM. Napolitano C et al Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias. Circulation. 2001;103(1):89-95. doi: 10.1161/01.cir.103.1.89. PMID: 11136691.
5.    Surekharani C. Shiddanna M. P. Anita Herur.A. Study of Cardiovascular Autonomic Functions in Congenitally Deaf Children with a Long QTC Interval. Journal of Clinical and Diagnostic research. 2011;5(4):804-807.
6.    Niaz A. Rizvi SF.  Khurram D. Prevalence of long QT syndrome and other cardiac defects in deaf-mute children. J Ayub Med Coll Abbottabad. 2011;23(1):5-8. PMID: 22830134.
7.    Ocal B. Imamoglu A. Atalay S. Ercan Tutar H. Prevalence of idiopathic long QT syndrome in children with congenital deafness. Pediatr Cardiol. 1997;18(6):401-5. doi: 10.1007/s002469900215. PMID: 9326683.
8.    Antzelevitch C. Yan GX. Shimizu W. Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome. J Electrocardiol. 1999;32 Suppl:158-65. doi: 10.1016/s0022-0736(99)90074-2. PMID: 10688320.
9.    Cusimano F. Martines E. Rizzo C. The Jervell and Lange-Nielsen syndrome. Int J Pediatr Otorhinolaryngol. 1991;22(1):49-58. doi: 10.1016/0165-5876(91)90096-t. PMID: 1917338.
10.    Sathyamurthy I.  Jayanthi K.  Dash J. Srinivasan KN. Long QT syndrome in children with congenital deafness. Indian Pediatr. 2009;46(6):507-8. Epub 2009 Jan 1. PMID: 19213984.
11.    Ilhan A. Tuncer C.  Komsuoglu SS. Kali S. Jervell and Lange-Nielsen syndrome: neurologic and cardiologic evaluation. Pediatr Neurol. 1999;21(5):809-13. doi: 10.1016/s0887-8994(99)00100-9. PMID: 10593671.
12.    Garson A.  Dick M.  Fournier A. Gillette PC.  Hamilton R. Kugler JD et al. The long QT syndrome in children. An international study of 287 patients. Circulation. 1993;87(6):1866-72. doi: 10.1161/01.cir.87.6.1866. PMID: 8099317.
13.    Tutar E.  Tekin M. Uçar T.  Comak E.  Ocal B.  Atalay S. Assessment of ventricular repolarization in a large group of children with early onset deafness. Pacing Clin Electrophysiol. 2004;27(9):1217-20. doi: 10.1111/j.1540-8159.2004.00612.x. PMID: 15461711.
14.    Chiang CE.  Roden DM. The long QT syndromes: genetic basis and clinical implications. J Am Coll Cardiol. 2000;36(1):1-12. doi: 10.1016/s0735-1097(00)00716-6. PMID: 10898405.
15.    T wave overview https://lifeinthefastlane.com/ecg-library/basics/t-wave/ accessed on 11/7/2017 at 11:35am.

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