Author(s): Rajashree Sriram, Gopal. V


DOI: 10.52711/0974-360X.2022.00230   

Address: Rajashree Sriram*, Gopal. V
Department of Pharmacognosy, Mother Theresa Post Graduate and Research Institute of Health Sciences, (A Govt of Puducherry Institution) Indira Nagar, Gorimedu, Puducherry - 605006.
*Corresponding Author

Published In:   Volume - 15,      Issue - 3,     Year - 2022

The most frequent dermatological concern and a multisystem degenerative process is skin aging. Age related factors may be either due to declining physiological functions (intrinsic aging) or may be due to environmental factors such as pollution, sun exposure, smoking, stress etc. (extrinsic aging). An aged skin displays pigmented lesions, patchy hypopigmentations, actinic keratoses, fragility, laxity and wrinkles. Skin aging mechanisms involve biochemical changes in collagen, elastin and connective tissues, thereby resulting in a thin, dry, less elastic, wrinkled skin. In the recent years, herbals are largely preferred to synthetic drugs regarding to their traditional use as they help in providing an efficient, low toxicity and cost impressive product. Though a number of traditional plants are available, novel delivery systems need to be integrated so that the efficacy and cost effectiveness of the therapy can be optimized. Functional herbal active constituents and innovative novel formulations are driving the cosmetic industry. This present review put forward extensively on herbs appraisal for skin aging treatment. It also highlights the benefits of herbals and their role in impeding aging of skin. Some commercial branded herbal anti-aging cosmeceuticals and a few novel anti-aging herbal formulations available in the market are also reviewed here.

Cite this article:
Rajashree Sriram, Gopal. V. Phytoformulation studies on Traditional Anti-Wrinkle Preparation. Research Journal of Pharmacy and Technology. 2022; 15(3):1378-4. doi: 10.52711/0974-360X.2022.00230

Rajashree Sriram, Gopal. V. Phytoformulation studies on Traditional Anti-Wrinkle Preparation. Research Journal of Pharmacy and Technology. 2022; 15(3):1378-4. doi: 10.52711/0974-360X.2022.00230   Available on:

1.    Gilchrest BA. Skin aging and photoaging. Dermatology Nursing. 1990; 2(2): 79–82.
2.    Joshi B, Agrawal P, Sahu D and Dashora A. Antiaging Cosmetics. Journal of Drug Delivery and Therapeutics. 2013; 3(3):158-162.
3.    Draelos ZD. Concepts in a multiprong approach to photoaging. Skin Therapy Letter. 2006; 11(3): 1-3.
4.    Kang S, Chung JH, Lee JH, et al. Topical N-acetyl cysteine and genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo. Journal of Investigative Dermatology. 2003; 120(5): 835-841.
5.    Chaudhari M and Mengi S. Evaluation of phytoconstituents of Terminalia arjuna for wound healing activity in rats. Phytotherapy Research. 2006; 20(9): 799-805.
6.    Burlando B, Verotta L, Cornara L, et al. Herbal Principles in Cosmetics: properties and mechanisms of action. CRC Press, New York.2010.
7.    Plants in Cosmetics. Council of Europe Publishing, Strassbourg Cedex; 2001.
8.    Alğın Yapar E, İnal Ö, Erdal S. Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil. Acta Pharmaceutica. 2013; 63(4): 531-44.
9.    Goleniowski ME, Bongiovanni GA, Palacio L, et al. Medicinal Plants from the “Sierra De Comechingones”, Argentina. Journal of Ethnopharmacology. 2006; 107(3): 324-341.
10.    Smita Kolhe, Mohini Upadhye, Priyanka Doke. Herbals Used in HIV: A Review. Research Journal of Pharmacology and Pharmacodynamics. 2013; 5(5): 275-282.
11.    Rathi V, Rathi JC, Tamizharasia S, et al. Plants used for hair growth promotion: A review. Pharmacognosy Reviews. 2008; 2(3): 185-187.
12.    Vaidiyanathan. R, B. Anand. Importance of Chemistry in Herbal Cosmetics and Cosmeceuticals. Research Journal of Pharmacy and Technology. 2017; 10(12): 4460-4462.
13.    Pande, SD, Joshi SB, Bobade NN, et al. Formulation and development of a liposome based hair revitalizer. Research Journal of Topical and Cosmetic Science. 2011; 2(1): 14-17.
14.    Sanjay Saklani, Deepak Prashar, Dharmesh Sharma. An Economical Overview on Herbal Cosmetics. Research Journal of Topical and Cosmetic Science. 3(1): Jan. –June 2012 page 4-10.
15.    Kapoor VP. Herbal Cosmetics For Skin And Hair Care. Natural Product Radiance. 2005; 4(4): 306-314.
16.    Kole PI, Jadhav HR, Thakurdesai P, et al. Cosmetics potential of herbal extracts. Natural Product Radiance. 2005; 4(4): 315–321.
17.    Chandrasekar. R. A Comprehensive Review on Herbal Cosmetics in the Management of Skin Diseases. Research Journal of Topical and Cosmetic Science. 2020; 11(1):32-44.
18.    Kim J, Kim G, et al. Study on effect of Skin Pore using Laser and Microcurrent Treatment. Research Journal of Pharmacy and Technology. 2018; 11(11): 4862-4865.
19.    Pankaj Sahu K, et al. Therapeutic and medicinal uses of aloe vera: A review. Journal of Pharmacology and Pharmacy. 2013; 4(8): 599-610.
20.    Jones K, Hughes J, Hong M, et al. Modulation of melanogenesis by aloesin: a competitive inhibitor of tyrosinase. Pigment Cell Research. 2002; 15(5): 335–340.
21.    Pulok Mukherjee K, et al. Bioactive compounds from natural resources against skin ageing. Journal of Phytomedicine. 2011; 19: 64-73.
22.    Hsu MF, Chiang BH. Stimulating effects of Bacillus subtilis natto-fermented Radix astragali on hyaluronic acid production in human skin cells. Journal of Ethnopharmacology. 2009; 125(3): 474–481.
23.    Shivanand Panday, et al. Herbs play an important role in the field of cosmetics. International Journal of PharmTech Research. 2010; 2(1):632-639.
24.    Majmudar G, Rogers KE. Skin lightening cosmetic containing magnesium ascorbyl phosphate and Uninontan-U34 (extract formulation of cucumber extract and lemon extract). 1999; PCT Int Appl 31: WO9949878
25.    Oh HI, Shim JS, Gwon SH, et al. The effect of xanthorrhizol on the expression of matrix metalloproteinase-1 and type-I procollagen in ultraviolet-irradiated human skin fibroblasts. Phytotherapy Research. 2009; 23(9): 1299–1302.
26.    Sumiyoshi M, Kimura Y. Effects of a turmeric extract (Curcuma longa) on chronic ultraviolet B irradiation-induced skin damage in melanin-possessing hairless mice. Phytomedicine. 2009; 16(12): 1137–1143.
27.    Bisht S, Feldmann G, Soni S, et al. Polymeric nanoparticle-encapsulated curcumin (“nanocurcumin”): a novel strategy for human cancer therapy, Journal of Nanobiotechnology. 2007; 5: 3.
28.    Naik GH, Priyadarsini KI, Mohan H. Radioprotecting ability and phytochemical analysis of an Indian medicinal plant: Terminalia chebula. BARC Newsletter(Founder's Day Special Issue). 2002; 1: 22-26.
29.    Kim SJ, Sancheti SA, Sancheti SS, et al. Effect of 1,2,3,4,6-penta-O-galloyl-beta-d-glucose on elastase and hyaluronidase activities and its type II collagen expression. Acta Poloniae. Pharmaceutica. 2010; 67(2): 145-150.
30.    Fujii T, Wakaizumi M, Ikami T, Saito M. Amla (Emblica officinalis Gaertn.) extract promotes procollagen production and inhibits matrix metalloproteinase-1 in human skin fibroblasts. Journal of Ethnopharmacology. 2008; 119(1): 53-7.
31.    Kim J, Hwang JS, Cho YK, et al. Protective effects of (-)-epigallocatechin-3-gallate on UVA- and UVB-induced skin damage. Skin Pharmacology and Applied Skin Physiology. 2001; 14(1): 11-9.
32.    Yuen Shan Ho, et al. Anti-aging herbal medicine - How and Why can they be used in ageing associated neurodegenerative diseases. Ageing Research Reviews. 2010; 9(3): 354-362.
33.    Cimino F, Cristani M, Saija A, et al. Protective effects of a red orange extract on UVB-induced damage in human keratinocytes. Biofactors. 2007; 30(2): 129–138.
34.    Lanny Parengkuan, et al. Anti-glycation activity of various fruits. Anti-Ageing Medicine. 2013; 10(4): 70-76.
35.    Jung E, Lee J, Baek J, et al. Effect of Camellia japonica oil on human type I procollagen production and skin barrier function. Journal of Ethnopharmacology. 2007; 112(1): 127-131.
36.    Kuldeep Rajpoot, Mishra RN. Boerhaavia diffusa roots (Punarnava Mool) - Review as Rasayan (Rejuvenator / antiaging). International Journal of Research in Pharmaceutical and Biomedical Sciences. 2011; 2(4): 1450-1460.
37.    Robin Mitra. Medicinal plants of Indonesia. Asia Pacific Biotech News. 2007; 11(11): 726-743.
38.    Tsoyi K, Hyung BP, Young MK, et al. Protective effect of anthocyanins from black soybean seed coats on UVB-induced apoptotic cell death in vitro and in vivo. Journal of Agricultural and Food Chemistry. 2008; 56(22): 10600–10605.
39.    Mio Hori, et al. Inhibition of advanced glycation end product formation by herbal teas and its relation to antiaging. Journal of Antiaging Medicine. 2012; 9(6): 35-145.
40. (Accessed on 29 Nov. 2010).
41.    Sable Namita V, Pagar Swati A. A review on Lotus: use in herbal cosmetics. Research Journal of Topical and Cosmetic Science. 2013; 4(1): 81-83.
42.    Mishra AK, Mishra A, Chattopadhyay P. Herbal Cosmeceuticals for photoprotection from ultraviolet B radiation: A Review. Tropical Journal of Pharmaceutical Research. 2011; 10(3): 351-360.
43.    Fathima A, Varma S, Jagannath P, Akash M. General review on herbal cosmetics. International Journal of Drug Formulation and Research. 2011; 2(5): 140-65.
44.    Rajashree H, Varsha P. Novel Anti-aging Technologies and Products. International Journal of Pharmaceutical and Chemical sciences. 2013; 2(4): 1756-61.
45.    Vender RB. Topical acne therapies: Optimizing patient compliance. Skin Therapy Letter - Family Practice. 2008; 4: 1-4.
46.    Savita M, Maitreyee C, et al. Liposomes: A Promising Future in Medicine. Asian Journal of Research in Chemistry. 2020; 13(4): 287-290.
47.    Abedon B. Consumers seeking nutricosmetics with multifunctional benefits. Las Vegas: West International Trade Show and Conference. 2009; 7-8.
48.    Corley JW. Natural and Organic: The Emerging Revolution. In Natural and Organics in Cosmetics: From R and D to the Marketplace. Edited by Lawrence BM, USA: Allured Publishing Corporation; 2007; pp. 55-66.
49.    Matthews I. Naturals hit mainstream. In Natural and organics in cosmetics: From R and D to the Marketplace. Edited by Lawrence BM, USA: Allured Publishing Corporation; 2007; pp. 17-20.
50.    Whittaker MH, Engimann E, Sambrook I. Eco-labels: Environmental marketing in the beauty industry. Global Cosmetic Industry. 2009; 177: 30-4.
51.    Tripathi S, Chaurey M, et al. Grewia asiatica Linn. - As a Phytomedicine: A Review. Research Journal of Pharmacy and Technology. 2010; 3(1): 1-3.
52.    Iroko Emamuzo M, Khokhlenkova N. The Use of Phytomedicines in Dentistry. Research Journal of Pharmacy and Technology. 2016; 9(5): 581-586.
53.    Bouidin AS, et al. Pharmacy and Herbal Medicine in the US. Social Science and Medicine. 1999; 49(2): 279-289.
54.    Farooqi AHA, Sharma S and Kumar S. Herbal Skin Care formulation and a process for the preparation thereof. U.S.Patent 6368639. 2002.
55.    Jadhav S, Sawale J. Standardization of Poly-herbal Formulations: A Comprehensive Review. Research Journal of Pharmacognosy and Phytochemistry. 2016; 8(2): 85-89.

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