Author(s): Amritha R., Sivakumar R., Y. Haribabu

Email(s): amritha.ar95@gmail.com , rrsk1879@gmail.com

DOI: 10.52711/0974-360X.2022.00227   

Address: Amritha R.1*, Sivakumar R.2, Y. Haribabu3
1Research Scholar, Grace College of pharmacy, Palakkad, Kerala-678004, India.
2Professor, Department of Pharmaceutics, Grace College of Pharmacy, Palakkad, Kerala-678004, India.
3Principal, Grace College of Pharmacy, Palakkad, Kerala-678004, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 3,     Year - 2022


ABSTRACT:
Advancement in chronopharmacology and the necessity of an appropriate technology for time specific and site specific drug delivery has led to the development of novel type of drug delivery systems as “chronotropic or Pulsatile drug delivery systems”. Rationale for designing pulsatile delivery systems is to release the drug at desired time, which results in improved therapeutic efficacy and patient-outcome. These systems are meant for treatment of those diseases that are caused due to circadian changes in body like asthma, peptic ulcer, cardiovascular diseases, arthritis and when zero order drug release is not desired. These pulsatile delivery systems a releases the drug within a short period of time, immediately after a predetermined lag time. The present article focuses on diseases requiring chronotropic systems and their chronological behaviour, various approaches, recent technologies for chronotherapy and currently available marketed formulations.


Cite this article:
Amritha R., Sivakumar R., Y. Haribabu. A Review on Pulsatile Drug Delivery System: Drug Scheduling based on Biological Rhythm. Research Journal of Pharmacy and Technology. 2022; 15(3):1359-4. doi: 10.52711/0974-360X.2022.00227

Cite(Electronic):
Amritha R., Sivakumar R., Y. Haribabu. A Review on Pulsatile Drug Delivery System: Drug Scheduling based on Biological Rhythm. Research Journal of Pharmacy and Technology. 2022; 15(3):1359-4. doi: 10.52711/0974-360X.2022.00227   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-70


REFERENCES:
1.    N. Mishra, et al. Targeted Drug Delivery: A Review. American Journal of Pharmtech Research. 2016; 6(1): 1-24
2.    Neha P Singh, et al. Pulsatile drug delivery system: A Review. World Journal of Pharmcy and Pharmaceutical Sciences. 2016; 5(5): 479-491
3.    M. Efentakis, et al. Design and evaluation of a dry coated drug delivery system with an impermeable cup, swellable top layer and pulsatile release. International Journal of Pharmaceutics. 2006; 311: 147–156.
4.    N. Rouge, et al. Drug Absorption Sites in the Gastrointestinal Tract and Dosage Forms for Site-specific Delivery. International Journal of Pharmaceutics. 1996; 136(1-2): 117–139.
5.    M. Halsas, et al. Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations. Int. J. Pharm. 1999; 189(2): 179–185.
6.    B. Lemmer. Chronopharmacokinetics: Implications for drug treatment. J. Pharm. Pharmacol. 1999; 51(8): 887–890.
7.    R. Nagaraju, et al. Core-in-cup tablet design of metoprolol succinate and its evaluation for controlled release. Curr. Drug Discov. Technol. 2009; 6(4): 299–305.
8.    Subhashis Debnath, G. Vijay Kumar, Debarshi Datta, D. Swetha, M. Niranjan Babu. Chronopharmaceutics as a novel approach for clinically relevant drug delivery system. Research J. Pharma. Dosage Forms and Tech. 2012; 4(6): 309-317.
9.    Sheth Avani, Naman Doshi, Dipen Patel, Badmanaban R, CN Patel. Footsteps of Pulsatile Drug Delivery System in Pharmaceutical Sciences. Research J. Pharm. and Tech. 2010; 3(2): 385-389
10.    Haribansh Narayan Singh, Shivangi Saxena, Sunil Singh, Ajit Kumar Yadav. Pulsatile Drug Delivery System: Drugs used in the Pulsatile Formulations. Research J. Pharma. Dosage Forms and Tech. 2013; 5(3): 115-121.
11.    Deepika Jain, et al. Recent Technologies in Pulsatile Drug Delivery Systems. Biomatter 2011; 1(1): 1-9
12.    Sayeed et al, IJPSR, 2013; 4(3): 960-969
13.    S., K.N. Survase. Pulsatile Drug Delivery: Current Scenario. CRIPS. 2007; 8(2): 27–33.
14.    Modi MP, Prasanth VV, Mathew ST. Pulsatile: A tool for circardian rhythm-A Review. Journal of Drug Delivery and Therapeutics. 2012 Jan 19; 2(1).
15.    Arora S, Ali J, Ahuja A, Baboota S, Qureshi J. Pulsatile drug delivery systems: An approach for controlled drug delivery. Indian Journal of Pharmaceutical Sciences. 2006; 68(3).
16.    Pallab Roy, Aliasgar Shahiwala. Multiparticulate formulation approach to pulsatile drug delivery: Current perspectives. Journal of Controlled Release. 2009; 134: 74-80
17.    Rajendra Asasthi et al. Chronotherapy: Science and Technology of drug scheduling on the basis of biological rhythm. Journal of Chronotherapy and Drug Delivery. 2010; 1(1): 09-18
18.    Anamika Singh et al. Pulsatile drug delivery system: an approach of medication according to circadian rhythm. Journal of Applied Pharmaceutical Science. 2012; 02(03): 166-176.
19.    Gurpreet Arora, Inderbir Singh, Manju Nagpal, Sandeep Arora. Recent Advances in Stimuli Induced Pulsatile Drug Delivery System: A Review. Research J. Pharm. and Tech. 2011; 4(5): 691-703
20.    M. Sukanya, V. Saikishore, P.Y. Shanmukha, K. Srikanth.. Novel Approaches for Pulsatile Drug Delivery System. Research J. Pharma. Dosage Forms and Tech. 2012; 4(4): 197-201.
21.    Sanjay S. Jain, Hemanshu V. Agarwal, Pramod S. Jagtap, Neha M. Dand, Kisan R. Jadhav, Vilasrao J. Kadam. Pulsatile drug delivery system (PDDS): A Brief Overview. Research J. Pharm. and Tech. 2012; 5(4): 449-461.
22.    Vidhi R Patel, Vipulbhai P Patel. Pulsatile drug delivery system-a review. International Journal of Pharmaceutical Sciences and Research. 2015; 6(9): 3676-3688.
23.    Ketousetuo Kuotsu, Biswas Nikhil. Drug delivery system based on chronobiology–A review. Journal of Controlled Release. 2010; 147: 314–325.
24.    Singh D. K., et al.Pulsatile Drug Delivery System: An Overview. International Journal of Current Pharmaceutical Review and Research. 2011; 2(2): 55-80.
25.    Singh Anamika, et al. Pulsatile Drug Delivery System: an Approach of Medication according to Circadian Rhythm. Journal of Applied Pharmaceutical Science. 2012; 2(3): 166-176.
26.    Ms. Shah Radhika, et al. Pulsatile Drug Delivery: A Review. Internationale Pharmaceutica Sciencia. 2012; 2(2): 45-52.
27.    Jatin Patel, Dipen Patel, Savan Vachhani, ST Prajapati, CN Patel. Current Status of Technologies and Devices for Chronotherapeutic Drug Delivery Systems. Research J. Pharm. and Tech. 2010; 3(2): 344-352.
28.    Moturi Vihar, Khan Arshad Bashir. Chronotherapeutics in Development of Pulsatile Delivery Systems. International Journal of Pharmaceutical Sciences and Research. 2012; 3(11): 4086-4095.
29.    Lida E. Kalantzi et al. Recent advances in oral pulsatile drug delivery. Recent Patents on Drug Delivery and Formulation. 2009; 3: 49-63.
30.    Seshni sewlall et al. A timely review of stat-of-art chronopharmaceuticals synchronized with biological rhythms 2010; 7: 370-388.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

0.38
2018CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank


Recent Articles




Tags


Not Available