Rupal S. Sanghavi, Omprakash Agrawal, Md. Rageeb Md. Usman
Rupal S. Sanghavi1*, Omprakash Agrawal2, Md. Rageeb Md. Usman3
1Ph.D Scholar, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P).
2Professor, Department of Pharmacy, Madhyanchal Professional University, Bhopal (M.P).
3Associate Professor, Department of Pharmacognosy, Smt. S.S Patil College of Pharmacy, Chopda (M.S.)
Volume - 15,
Issue - 3,
Year - 2022
Oral route is considered as the most convenient, accepted and safest way for drug delivery, achieving better therapeutic effectiveness by delivery of drug at specific site in controlled manner is getting more attention now a days and GRDDS is one of the novel approaches which prolongs gastric residence time and releases a drug at specific targeted site of stomach for local or systemic effects. This approach is useful for drugs having narrow absorption window in upper part of GI tract. In this review we have discussed various aspects of GRDDS like merits, demerits, physiology of stomach, and potential drug candidate for GRDDS, factors affecting gastric retention, polymers and other materials used in GRDDS, Various approaches for gastric retention and evaluation of GRDDS concisely.
Cite this article:
Rupal S. Sanghavi, Omprakash Agrawal, Md. Rageeb Md. Usman. Gastroretentive Drug Delivery System: An Overview. Research Journal of Pharmacy and Technology. 2022; 15(3):1343-7. doi: 10.52711/0974-360X.2022.00224
Rupal S. Sanghavi, Omprakash Agrawal, Md. Rageeb Md. Usman. Gastroretentive Drug Delivery System: An Overview. Research Journal of Pharmacy and Technology. 2022; 15(3):1343-7. doi: 10.52711/0974-360X.2022.00224 Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-67
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