Author(s): Chew Khe Jiea, Shivkanya Fuloria, Vetriselvan Subrimanyan, Mahendran Sekar, Kathiresan V. Sathasivam, Saminathan Kayarohanam, Yuan Seng Wu, Venkata Sathya Saiappala Raju Velaga, Ashok Kumar Janakiraman, Mohammad Nazmul Hasan Maziz, Neeraj Kumar Fuloria

Email(s): neerajkumar@aimst.edu.my

DOI: 10.52711/0974-360X.2022.00205   

Address: Chew Khe Jiea1, Shivkanya Fuloria1, Vetriselvan Subrimanyan2, Mahendran Sekar3, Kathiresan V. Sathasivam4, Saminathan Kayarohanam5, Yuan Seng Wu6, Venkata Sathya Saiappala Raju Velaga7, Ashok Kumar Janakiraman8, Mohammad Nazmul Hasan Maziz2, Neeraj Kumar Fuloria1*
1Faculty of Pharmacy, AIMST University, Kedah 08100, Malaysia.
2Faculty of Medicine, Bioscience and Nursing, MAHSA University, Bandar Saujana Putra 42610, Malaysia.
3Faculty of Pharmacy and Health Sciences, Universiti Kuala Lumpur Royal College of Medicine Perak, Ipoh 30450, Malaysia.
4Faculty of Applied Science, AIMST University, Kedah 08100, Malaysia.
5Faculty of Bio-economy and Health Sciences, Geomatika University College Kuala Lumpur 54200, Malaysia.
6Centre for Virus and Vaccine Research & Department of Biological Sciences, School of Medical and Life Sciences, Sunway University, Subang Jaya, Selangor, Malaysia.
7Faculty of Pharmacy, MAHSA University, Bandar Saujana Putra 42610, Malaysia.
8Faculty of Phar

Published In:   Volume - 15,      Issue - 3,     Year - 2022


ABSTRACT:
Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44µg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts.


Cite this article:
Chew Khe Jiea, Shivkanya Fuloria, Vetriselvan Subrimanyan, Mahendran Sekar, Kathiresan V. Sathasivam, Saminathan Kayarohanam, Yuan Seng Wu, Venkata Sathya Saiappala Raju Velaga, Ashok Kumar Janakiraman, Mohammad Nazmul Hasan Maziz, Neeraj Kumar Fuloria. Phytochemical screening and Antioxidant activity of Cananga odorata extract. Research Journal of Pharmacy and Technology. 2022; 15(3):1230-4. doi: 10.52711/0974-360X.2022.00205

Cite(Electronic):
Chew Khe Jiea, Shivkanya Fuloria, Vetriselvan Subrimanyan, Mahendran Sekar, Kathiresan V. Sathasivam, Saminathan Kayarohanam, Yuan Seng Wu, Venkata Sathya Saiappala Raju Velaga, Ashok Kumar Janakiraman, Mohammad Nazmul Hasan Maziz, Neeraj Kumar Fuloria. Phytochemical screening and Antioxidant activity of Cananga odorata extract. Research Journal of Pharmacy and Technology. 2022; 15(3):1230-4. doi: 10.52711/0974-360X.2022.00205   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-48


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