Author(s): Mahavir Singh, H. Sawarkar, Birendra Shrivastav, Bakal

Email(s): vedanshumlv56@gmail.com

DOI: 10.52711/0974-360X.2022.00988   

Address: Mahavir Singh, H. Sawarkar*, Birendra Shrivastav, Bakal
Department of Pharmaceutical Chemistry, School of Pharmacy, Jaipur National University, Jaipur.
Department of Pharmaceutical Chemistry, Dr. Rajendra Gode Institute of Pharmacy, Amravati.
*Corresponding Author

Published In:   Volume - 15,      Issue - 12,     Year - 2022


ABSTRACT:
1, 2, 4-Triazoles and their derivatives have a distinct place in the field of medicinal and pharmaceutical chemistry. These are used as lead compounds for the synthesis of numerous heterocyclic compounds which possess diverse biological activities and play pivotal roles. This review covers the latest literature and knowledge on the synthetic procedures for various triazoles derivatives, their activities and pharmacological applications. The synthetic routes of 1, 2, 4-triazole compounds as well as their pharmacological properties have been described. The review focuses intensively on two methods: cyclo-addition reaction in the syntheses of various 1, 5-dialky-1H-1, 2, 4-triazole derivatives from the reactive cumulenes with the nitrile precursors as well as the microwave irradiation method.


Cite this article:
Mahavir Singh, H. Sawarkar, Birendra Shrivastav, Bakal. A Review on Synthetic Approaches and Activities of 1, 2, 4-Triazoles. Research Journal of Pharmacy and Technology 2022; 15(12):58574-8. doi: 10.52711/0974-360X.2022.00988

Cite(Electronic):
Mahavir Singh, H. Sawarkar, Birendra Shrivastav, Bakal. A Review on Synthetic Approaches and Activities of 1, 2, 4-Triazoles. Research Journal of Pharmacy and Technology 2022; 15(12):58574-8. doi: 10.52711/0974-360X.2022.00988   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-12-82


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