Author(s): N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya

Email(s): gayatridevi@saveetha.com

DOI: 10.52711/0974-360X.2022.00920   

Address: N. Vishal Prakasam1, Gayatri Devi. R2, J. Selvaraj3, A. Jothi Priya4
1Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS) Saveetha University, Chennai – 600077.
2Associate Professor, Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
3Associate Professor, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
4Assistant Professor, Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
*Corresponding Author

Published In:   Volume - 15,      Issue - 12,     Year - 2022


ABSTRACT:
Background: Mimosa pudica commonly known as the “Touch me not” originated from the family “mimosaceae”. Mimosa pudica possesses a lot of medicinal values such as anti-bacterial, anti-fungal, anti-diabetic properties etc. Euphorbia hirta is commonly known for curing patients suffering from asthma hence the name “Asthma plant”. It has various medicinal properties such as anti-fungal,anti-bacterial,anti-diabetic etc. Both these plants has anti-diabetic property hence the present was done to compare which medicinal herb is a better replacement for the standard synthetic drug “Metformin”. Materials and Methods: Assessment of in vitro anti-diabetic activity of Mimosa pudica and Euphorbia hirta was performed by alpha-amylase inhibitory activity and alpha-glucosidase inhibitory activity. The result was compared to the standard drug metformin. The data were analysed statistically using one way analysis of variance (ONE-WAY ANOVA). Duncan Multiple range test was used to analyze the statistical significance between groups. The levels of significance were considered at the levels of p<0.05. Result: Both the plants showed an increase in percentage on inhibition of alpha amylase and alpha glucosidase in dose dependent manner. Conclusion: In the present study, it was revealed that the medicinal plant Euphorbia hirta showed a better antidiabetic activity than Mimosa pudica.


Cite this article:
N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya. In-vitro Antidiabetic on leaf extracts of Mimosa pudica and Euphorbia hirta - A Comparative Study. Research Journal of Pharmacy and Technology2022; 15(12):5459-3. doi: 10.52711/0974-360X.2022.00920

Cite(Electronic):
N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya. In-vitro Antidiabetic on leaf extracts of Mimosa pudica and Euphorbia hirta - A Comparative Study. Research Journal of Pharmacy and Technology2022; 15(12):5459-3. doi: 10.52711/0974-360X.2022.00920   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-12-14


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