N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya
N. Vishal Prakasam1, Gayatri Devi. R2, J. Selvaraj3, A. Jothi Priya4
1Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS)
Saveetha University, Chennai – 600077.
2Associate Professor, Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
3Associate Professor, Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
4Assistant Professor, Department of Physiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai – 600077.
Volume - 15,
Issue - 12,
Year - 2022
Background: Mimosa pudica commonly known as the “Touch me not” originated from the family “mimosaceae”. Mimosa pudica possesses a lot of medicinal values such as anti-bacterial, anti-fungal, anti-diabetic properties etc. Euphorbia hirta is commonly known for curing patients suffering from asthma hence the name “Asthma plant”. It has various medicinal properties such as anti-fungal,anti-bacterial,anti-diabetic etc. Both these plants has anti-diabetic property hence the present was done to compare which medicinal herb is a better replacement for the standard synthetic drug “Metformin”. Materials and Methods: Assessment of in vitro anti-diabetic activity of Mimosa pudica and Euphorbia hirta was performed by alpha-amylase inhibitory activity and alpha-glucosidase inhibitory activity. The result was compared to the standard drug metformin. The data were analysed statistically using one way analysis of variance (ONE-WAY ANOVA). Duncan Multiple range test was used to analyze the statistical significance between groups. The levels of significance were considered at the levels of p<0.05. Result: Both the plants showed an increase in percentage on inhibition of alpha amylase and alpha glucosidase in dose dependent manner. Conclusion: In the present study, it was revealed that the medicinal plant Euphorbia hirta showed a better antidiabetic activity than Mimosa pudica.
Cite this article:
N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya. In-vitro Antidiabetic on leaf extracts of Mimosa pudica and Euphorbia hirta - A Comparative Study. Research Journal of Pharmacy and Technology2022; 15(12):5459-3. doi: 10.52711/0974-360X.2022.00920
N. Vishal Prakasam, Gayatri Devi. R, J. Selvaraj, A. Jothi Priya. In-vitro Antidiabetic on leaf extracts of Mimosa pudica and Euphorbia hirta - A Comparative Study. Research Journal of Pharmacy and Technology2022; 15(12):5459-3. doi: 10.52711/0974-360X.2022.00920 Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-12-14
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