Author(s):
Madhavi Patel, Shivangi Chauhan, Vishal Patel, Hardik Soni, Vikram Trivedi
Email(s):
vishalpatel@vasuresearch.com
DOI:
10.52711/0974-360X.2022.00877
Address:
Madhavi Patel1, Shivangi Chauhan1, Vishal Patel2*, Hardik Soni2, Vikram Trivedi2
1Parul Institute of Pharmacy, Faculty of Pharmacy, Parul University, Vadodara, Gujarat, India.
2Vasu Research Centre (A Div. of Vasu Healthcare Pvt. Ltd.), Vadodara, Gujarat, India.
*Corresponding Author
Published In:
Volume - 15,
Issue - 11,
Year - 2022
ABSTRACT:
Traditional systems of medicine gain upsurge with the estimated 80% preference for maintenance of healthcare in the entire world. As a rich source for the treatment of diseases, Ayurvedic medicine’s consumption have increased day by day which has led to an increase in various forms of adulteration in raw materials. In a view of increasing demand, it is very crucial to maintain batch-to-batch consistency and efficacy avoiding adulteration and safety issues. Thus, standardization of Ayurvedic medicine in all aspects including phytochemical profiling becomes crucial for the manufacturer. So, the present study portrays standardization of an Ayurvedic proprietary laxative tablet comprising Yashtimadhu, Swarnpatri and Aragvadha as major components. General parameters of tablet were evaluated as per Indian Pharmacopoeia method for quality control purpose. For quantification of phytoconstituents, Sennoside-B was selected as a phytomarker of Swarnpatri & Aragvadha and Monoammonium glycyrrhizinate was selected as a phytomarker of Yashtimadhu. Both the markers were effectively quantified using HPTLC method. The Sennoside B and Monoammonium glycyrrhizinate contents in formulation were found to be 5.10 % and 0.634 % w/w, respectively. These standardization tools will help in maintaining the quality and consistency of this vital Ayurvedic formulation.
Cite this article:
Madhavi Patel, Shivangi Chauhan, Vishal Patel, Hardik Soni, Vikram Trivedi. Standardization of Proprietary Ayurvedic Laxative Tablet Formulation – Vasulax. Research Journal of Pharmacy and Technology. 2022; 15(11):5206-0. doi: 10.52711/0974-360X.2022.00877
Cite(Electronic):
Madhavi Patel, Shivangi Chauhan, Vishal Patel, Hardik Soni, Vikram Trivedi. Standardization of Proprietary Ayurvedic Laxative Tablet Formulation – Vasulax. Research Journal of Pharmacy and Technology. 2022; 15(11):5206-0. doi: 10.52711/0974-360X.2022.00877 Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-11-62
REFERENCES:
1. Anupam KS, Garima V, Roopak K. Need of Standardization of Herbal Medicines in Modern Era. International Journal of Phytomedicine. 2016 July 1; 8(3): 300-7. doi: 10.5138/09750185.1847.
2. Anita SW, et al. Evaluation and Standardization of Herbal Formulation. Research Journal of Pharmacognosy and Phytochemistry. 2016 July 1; 8(4): 133-40. doi: 10.5958/0975-4385.2016.00024.8.
3. Neelesh D, Manoj T, Ashok KT. Standardization and Quality Control of Dadimastaka Curna – An Ayurvedic Medicine. Research Journal of Pharmacognosy and Phytochemistry. 2015 April 1; 7(2): 111-15. doi: 10.5958/0975-4385.2015.00019.9.
4. Jain V, Jain T, Swarnlata S, Saraf S. HPTLC method for routine quality control of Ayurvedic formulation Drakshadi gutika. Asian Journal of Pharmaceutical Analysis. 2013 October 1; 3(4): 111-14. Available on: https://ajpaonline.com/AbstractView.aspx?PID=2013-3-4-1.
5. Ajit KT, Pooja R. Pharmacological Perspective of Glycyrrhiza glabra Linn.: A Mini-Review. Journal of Analytical & Pharmaceutical Research. 2017 August 4; 5(5): 156. doi: 10.15406/japlr.2017.05.00156.
6. Kavya R. Glycyrrhiza glabra - An Ayurvedic Medicine in Dentistry. Research Journal of Pharmacy and Technology. 2014 July 1; 7(7): 821-22. Available on https://rjptonline.org/HTMLPaper.aspx?Journal=Research+Journal+of+Pharmacy+and+Technology%3bPID%3d2014-7-7-10.
7. Rajandeep K, Harpreet K, Ajaib SD. Glycyrrhiza Glabra: A Phytopharmacological Review. International Journal of Pharmaceutical Sciences and Research. 2013 July 1; 4(7): 2470-77. doi: 10.13040/IJPSR.0975-8232.4(7).2470-77.
8. Khare P, Kishore K, Sharma DK. A Study on the Standardization Parameters of Cassia angustifolia. Asian Journal of Pharmaceutical and Clinical Research. 2017 July 1; 10(7): 329–32. doi: 10.22159/ajpcr.2017.v10i7.18394.
9. Ramchander JP, Jalwal P, Middha A. (2017) Recent Advances on Senna as a Laxative: A Comprehensive Review. Journal of Pharmacognosy and Phytochemistry. 2017 March 1; 6(2): 349–53. Available on https://www.phytojournal.com/archives/2017/vol6issue2/PartF/6-2-92-932.pdf.
10. Anonymous. The Ayurvedic pharmacopoeia of India. Part-I, Volume-IX. Government of India, Ministry of AYUSH, New Delhi. 2016; pp 92–94.
11. Kushawaha M, Agrawal RC. Biological Activity of Medicinal Plant Cassia fistula – A Review. Journal of Scientific Research in Pharmacy. 2012 September 1; 1(3): 7–11. doi: 10.13140/RG.2.2.18492.44167.
12. Manisha AN, et al. Pharmacological and Phytochemical Review on Cassia fistula. Research Journal of Pharmacy and Technology. 2011 February 1; 4(2): 214-22. Available on https://rjptonline.org/AbstractView.aspx?PID=2011-4-2-31.
13. Sharma DK. Enumerations on Phytochemical, Pharmacological and Ethnobotanical Properties of Cassia fistula linn: Yellow Shower. The Journal of Phytopharmacology. 2017 September 1; 6(5): 300–306. Aavailable on http://www.phytopharmajournal.com/Vol6_Issue5_09.pdf.
14. Manisha AN, et al. Pharmacological and Phytochemical Review on Cassia fistula. Research Journal of Pharmacy and Technology. 2011 February 1; 4(2): 214-22. Available on: https://rjptonline.org/AbstractView.aspx?PID=2011-4-2-31.
15. Jamuna S, Paulsamy S. HPTLC Fingerprints of Various Secondary Metabolites in the Traditional Medicinal Herb Hypochaeris radicata L. Journal of Botany. 2016 February 14; 1-12. doi: 10.1155/2016/5429625.
16. Anonymous. Indian Pharmacopoeia. Ministry of Health and Family Welfare, Government of India, New Delhi. 2018.
17. Tapan KG, et al. In-vitro quality control measurement of some commercially available sustained release tablet containing diclofenac sodium. Research Journal of Pharmacy and Technology. 2012 May 1; 5(5): 687-90. Available on: https://rjptonline.org/AbstractView.aspx?PID=2012-5-5-9.
18. Vamshi KT, et al. Study of Various Physical Parameters of Marketed Products of Paracetamol. Research Journal of Pharmaceutical Dosage Forms and Technology. 2013 July 1; 5(4): 227-231. Available on: https://rjpdft.com/AbstractView.aspx?PID=2013-5-4-6.
19. Anonymous. Quality Standards of Indian Medicinal Plants. Volume-9. Medical Plants Unit ICMR, New Delhi. 2011; pp 175-86.
20. Anonymous. Quality Standards of Indian Medicinal Plants. Volume-1. Medical Plants Unit ICMR, New Delhi. 2003; pp 57-64.
21. Anonymous. Quality Standards of Indian Medicinal Plants. Volume-2. Medical Plants Unit ICMR, New Delhi, 2005; pp 47-53.
22. Chetan S, et al. Development of an Analytical Method to Determine Extracts of Different Species of Glycyrrhizin by HPTLC. Research Journal of Pharmaceutical Dosage Forms and Technology. 2020 April 1; 12(2): 89-92. doi: 10.5958/0975-4377.2020.00016.6.
23. Tapadiya GG, et al. Quantitative Estimation of Sennoside B from Capsule Dosage Form by HPTLC. Research Journal of Pharmacy and Technology. 2019 January 1; 2(1): 97-100. Available on https://rjptonline.org/AbstractView.aspx?PID=2009-2-1-52.