Author(s): Juliet Tangka, Elisabeth N. Barung, Diana Lyrawati, Djoko W. Soeatmadji, Nurdiana

Email(s): juliet.tangka@gmail.com , elisabeth.barung1225@gmail.com , diana.l@ub.ac.id , djokowahono@ub.ac.id , nurdianafarmako.fk@ub.ac.id

DOI: 10.52711/0974-360X.2022.00869   

Address: Juliet Tangka1,2, Elisabeth N. Barung2, Diana Lyrawati3*, Djoko W. Soeatmadji4, Nurdiana5
1Doctoral Program of Medical Science, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
2Department of Pharmacy, Politeknik Kesehatan, Kementerian Kesehatan Manado, Manado, Indonesia.
3Department of Pharmacy, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
4Department of Internal Medicine, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
5Department of Pharmacology, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 11,     Year - 2022


ABSTRACT:
Abelmoschus manihot L. Medic, commonly called ‘‘red gedi’’, is an endemic species of Minahasa, Indonesia. The leaves of red gedi have been widely used in ethnomedicine and functional food as an antidiabetic. In this study, the ethanolic extract of the red gedi leaves was characterized by using liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (LC–ESI-MS). Compounds identified were phenolic acid derivates, flavonoids, terpenoids, phytosterols, alkaloids, and lignans. The most abundant flavonoids in the extract sample were quercetin derivatives. In total, 38 metabolite compounds were identified in red gedi leaves and were reported for the first time, including alpha spinasterol which is newly identified in this particular Abelmoschus species.


Cite this article:
Juliet Tangka, Elisabeth N. Barung, Diana Lyrawati, Djoko W. Soeatmadji, Nurdiana. Identification of metabolite compounds from ethanolic extract of the Red Gedi Leaves (Abelmoschus manihot L. Medik) by LC-ESI-MS. Research Journal of Pharmacy and Technology. 2022; 15(11):5164-7. doi: 10.52711/0974-360X.2022.00869

Cite(Electronic):
Juliet Tangka, Elisabeth N. Barung, Diana Lyrawati, Djoko W. Soeatmadji, Nurdiana. Identification of metabolite compounds from ethanolic extract of the Red Gedi Leaves (Abelmoschus manihot L. Medik) by LC-ESI-MS. Research Journal of Pharmacy and Technology. 2022; 15(11):5164-7. doi: 10.52711/0974-360X.2022.00869   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-11-54


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