Author(s): Rita Kartika Sari, Maeda Wahyuningrum, Salman Arib Rozan, M. Ilham Aulia, Mohamad Rafi, Ietje Wientarsih

Email(s): rita_kartikasari@apps.ipb.ac.id

DOI: 10.52711/0974-360X.2022.00858   

Address: Rita Kartika Sari1,4*, Maeda Wahyuningrum1, Salman Arib Rozan1, M. Ilham Aulia1, Mohamad Rafi2,4, Ietje Wientarsih3
1Department of Forest Products, Faculty of Forestry and Environment, IPB University, Bogor 16680, Indonesia.
2Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor 16680, Indonesia.
3Department of Clinic, Reproduction, and Pathology, IPB University, Bogor 16680, Indonesia.
4Tropical Biopharmaca Research Center, IPB University, Bogor 16128, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 11,     Year - 2022


ABSTRACT:
This study aimed to determine antioxidant activity (AA), sunscreen activity (SA), and phytochemical profiles of G. versteegii leaf extracts from West Java (WJ) and Central Java (CJ) and its phytosome. The samples were extracted using the maceration method with 50% ethanol (E50). The AA of extracts was evaluated using in vitro assay with the 2,2-diphenyl-l-picrylhydrazyl (DPPH) and cupric reducing antioxidant capacity (CUPRAC) methods. The SA of extracts was expressed as a sun protection factor (SPF). The result showed that the E50 extract from WJ was the higher of yield, AA, SPF, and total phenolic content (TPC) about 25.4%, 38.92 µmol-trolox/g (DPPH) and 768.93 µmol-trolox/g (CUPRAC), 14.84 (classified as maximum), and 77.01 mg gallic acid equivalent (GAE)/g sample, respectively. The phytosome formulas were made with different ratios of E50 extract and soy lecithin of F1 (1:2), F2 (1:1), and F3 (2:1). The best phytosome formula was the F2 (ratio of extract: lecithin was 1:1) with the yield, AA, SPF, and TPC was 85.47%, 1535.1 µmol-trolox/g (CUPRAC), 13.74 (classified as maximum), and 174 mg GAE/g, respectively. TPC of the extract and phytosome was positively correlated with AA.


Cite this article:
Rita Kartika Sari, Maeda Wahyuningrum, Salman Arib Rozan, M. Ilham Aulia, Mohamad Rafi, Ietje Wientarsih. In Vitro Antioxidant and Sunscreen Activities of Gyrinops versteegi Leaf Extract from Different Location in Indonesia and Phytosome Combinations. Research Journal of Pharmacy and Technology. 2022; 15(11):5106-5111. doi: 10.52711/0974-360X.2022.00858

Cite(Electronic):
Rita Kartika Sari, Maeda Wahyuningrum, Salman Arib Rozan, M. Ilham Aulia, Mohamad Rafi, Ietje Wientarsih. In Vitro Antioxidant and Sunscreen Activities of Gyrinops versteegi Leaf Extract from Different Location in Indonesia and Phytosome Combinations. Research Journal of Pharmacy and Technology. 2022; 15(11):5106-5111. doi: 10.52711/0974-360X.2022.00858   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-11-43


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