Author(s): SM Abdul Aziz Barbhuiya, Ajay Kakati, Muslek Uddin Mazumder, Md Rejwan Ahmed Choudhury, Mosrur Ahmed Laskar

Email(s): smazizbarbhuiya53@gmail.com

DOI: 10.52711/0974-360X.2022.00851   

Address: SM Abdul Aziz Barbhuiya1*, Ajay Kakati2, Muslek Uddin Mazumder1, Md Rejwan Ahmed Choudhury3, Mosrur Ahmed Laskar1
1University of Science and Technology, Ri-Bhoi, Meghalaya – 793101.
1NETES Institute of Pharmaceutical Science, Mirza, 781125, Assam, India.
2College of Veterinary Sciences, AAU, Khanapara, Guwahati, India.
3Assam Downtown University, Panikhati, Guwahati, India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 11,     Year - 2022


ABSTRACT:
Aim: The current research was planned to explore the diverse pharmacognostic standards of unexplored traditionally used medicinal plants from Northeast India (Alpinia galanga, Chenopodium album, Mikania micrantha, Allium hookeri, & Eryngium foetidium). Materials and Methods: Leaves samples were collected, authenticated, elaborative studies by macroscopic, microscopic, and physicochemical characterization (As per WHO-recommended methods of standardization), and methanolic extracts were prepared. The anti-oxidant and anti-inflammatory action of the leaves extracts were also resolute by the DPPH assay with butylated hydroxyl anisole as benchmark and inhibition of protein denaturation method taking diclofenac sodium as a standard drug respectively. Results: The pharmacognostic and physicochemical parameters enable to evaluate purity and avoid adulteration of the crude drugs. Methanolic extract of Eryngium foetidium(MMEF) showed better antioxidant activity and methanolic extract of Alpinia galangal(MMAG) showed profound anti-inflammatory activity amongst all extracts. Conclusion: This study showed preliminary pharmacognostic standards for traditionally used medicinal plants and therapeutic information which would be good tools for future experimental biological activity study, together with the need for drug discovery and development.


Cite this article:
SM Abdul Aziz Barbhuiya, Ajay Kakati, Muslek Uddin Mazumder, Md Rejwan Ahmed Choudhury, Mosrur Ahmed Laskar. The pharmacognostic profiling of traditionally used medicinal plants of Northeast India and evaluation of their in-vitro anti-oxidant and anti- inflammatory potential. Research Journal of Pharmacy and Technology. 2022; 15(11):5062-7. doi: 10.52711/0974-360X.2022.00851

Cite(Electronic):
SM Abdul Aziz Barbhuiya, Ajay Kakati, Muslek Uddin Mazumder, Md Rejwan Ahmed Choudhury, Mosrur Ahmed Laskar. The pharmacognostic profiling of traditionally used medicinal plants of Northeast India and evaluation of their in-vitro anti-oxidant and anti- inflammatory potential. Research Journal of Pharmacy and Technology. 2022; 15(11):5062-7. doi: 10.52711/0974-360X.2022.00851   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-11-36


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