Author(s): Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood‎, Ashour H. Dawood

Email(s): shahla@esraa.edu.iq , sara.ashour@esraa.edu.iq , dr.ashouralsaedi@gmail.com

DOI: 10.52711/0974-360X.2022.00734   

Address: Shahlaa Zuhair Abdul-Majeed*, Sarah A. Hamood‎, Ashour H. Dawood
Al-Esraa University College, Baghdad, Iraq.
*Corresponding Author

Published In:   Volume - 15,      Issue - 10,     Year - 2022


ABSTRACT:
The used Resveratrol-Thiadiazol derivatives (A, B, C) were prepared and characterized by 1H-13C NMR and FT-IR spectroscopies. This study used two cell lines for cytotoxicity testing: ?MCF-7 (Human Breast Cancer Cells) and WRL-68 (Human Normal Liver Cells), The result of anticancer study showed ?that derivative C had significant selectivity on MCF-7 used in this study even in very low concentration used to evaluate ?the anticancer activity while derivatives A and B showed non-significant selectivity on MCF-7 in low concentration while ?in high concentration showed small selectivity which may be negligible, this selectivity determined according to the ?comparison between: MCF-7 (Human Breast Cancer Cells) and WRL-68 (Human Normal Liver Cells).?


Cite this article:
Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood‎, Ashour H. Dawood. Studying the Anti-Cancer Activity of Resveratrol 1,3,4-Thiadiazol ‎Derivatives ‎. Research Journal of Pharmacy and Technology2022; 15(10):4377-1. doi: 10.52711/0974-360X.2022.00734

Cite(Electronic):
Shahlaa Zuhair Abdul-Majeed, Sarah A. Hamood‎, Ashour H. Dawood. Studying the Anti-Cancer Activity of Resveratrol 1,3,4-Thiadiazol ‎Derivatives ‎. Research Journal of Pharmacy and Technology2022; 15(10):4377-1. doi: 10.52711/0974-360X.2022.00734   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-10-7


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