Author(s): Ekhlass M. Taha, Muzahem Mohialdeen Taha, Jinan Hameed Abu-Shana, Saleh M. Rahim, Mays Mohammed Abdullah

Email(s): ekhlassch@yahoo.com , ikhlasmb_chem@csw.uobaghdad.edu.iq

DOI: 10.52711/0974-360X.2022.00795   

Address: Ekhlass M. Taha1*, Muzahem Mohialdeen Taha2, Jinan Hameed Abu-Shana3, Saleh M. Rahim4, Mays Mohammed Abdullah5
1University of Baghdad College of Science for Women Department of Chemistry,Al-Jadriya, Baghdad, Iraq, Postal Codes: 10071.
2Kirkuk University, Kirkuk, Iraq: Postal Codes: 36001. Consultant Orthopedic and Spine Surgeon- Erbil International Hospital.
3Al-Iraqia University- College of Medicine, Baghdad, Iraq, Postal Codes: 10053.
4Kirkuk University, Kirkuk, Iraq: Postal Codes: 36001.
5University of Baghdad College of Science for women Department of Chemistry, Al-Jadriya, Baghdad, Iraq.
*Corresponding Author

Published In:   Volume - 15,      Issue - 10,     Year - 2022


ABSTRACT:
Background and Objectives: The frequency of Brucellosis is expanding in the Middle East particularly in Iraq. Spondylitis is the most incessant difficulty, yet it is hard to analyze in light of the fact that its clinical side effects are vague. The cross-sectional study was conducted to evaluate abnormal serum protein electrophoresis patience living with brucellar spondylitis and it is related to the disease. This study shares out the distribution of protein pattern in Brucellar spondylitis patients. Methods: The current study included a total number of 40 voluntary subjects covers of 25 cases and 15 controls. Total serum protein was determined using the biuret method, serum albumin was determined using bromocresol green method, Serum protein electrophoresis was determined using SAS-MX serum protein gel. Results: Total proteins, Alpha 1 Globulin, and Gamma Globulin were significantly increased in Brucellar spondylitis when compared to controls. Ratio Albumin/Gamma was significantly decreased in Brucellar spondylitis compared to control. Albumin, Alpha 2 Globulin, and Beta Globulin did not appear significant difference. According to the multivariable regression analysis the level of Alpha 1 Globulin was highly related to total protein in Brucellar spondylitis. The cluster analysis showed that the investigated parameters organized into four clusters in the serum of patients with Brucellar spondylitis. Conclusion: we conclude that Total proteins, Alpha 1 Globulin, and Gamma Globulin have altered in patients Brucellar spondylitis when compared to control, Also Alpha 1 Globulin was associated with total protein in the studied cases.


Cite this article:
Ekhlass M. Taha, Muzahem Mohialdeen Taha, Jinan Hameed Abu-Shana, Saleh M. Rahim, Mays Mohammed Abdullah. Brucellar Spondylitis causes Alteration in Serum protein and Electrophoretic pattern. Research Journal of Pharmacy and Technology 2022; 15(10):4733-8. doi: 10.52711/0974-360X.2022.00795

Cite(Electronic):
Ekhlass M. Taha, Muzahem Mohialdeen Taha, Jinan Hameed Abu-Shana, Saleh M. Rahim, Mays Mohammed Abdullah. Brucellar Spondylitis causes Alteration in Serum protein and Electrophoretic pattern. Research Journal of Pharmacy and Technology 2022; 15(10):4733-8. doi: 10.52711/0974-360X.2022.00795   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-10-68


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