Author(s): Husnawati, Elin Yulinah Sukandar, Kusnandar Anggadiredja


DOI: 10.52711/0974-360X.2022.00060   

Address: Husnawati1,2*, Elin Yulinah Sukandar1, Kusnandar Anggadiredja1
1School of Pharmacy, Institut Teknologi Bandung, Bandung 40132, Indonesia.
2Sekolah Tinggi Ilmu Farmasi Riau, Pekanbaru, Riau, Indonesia.
*Corresponding Author

Published In:   Volume - 15,      Issue - 1,     Year - 2022

Hypertension is a risk factor for cardiovascular disease. Several studies have shown that control of hypertension is still low, and the main reason is the low medication adherence to taking medication for patients, especially in rural areas. It can lead to treatment failure, consequently increasing morbidity and mortality. The purpose of this study is to describe the adherence to medication and observance the characteristics of hypertensive patients in rural areas. A cross-sectional design is used in this study. It was adopted to facilitate the survey of hypertensive patients in rural areas. This research was conducted in several districts in the city of Pekanbaru which is a rural area. The sample consisted of 220 patients with hypertension using the quota sampling technique. The characteristics of patients were measured using a validated questionnaire, and patient adherence was measured by the MGL (Morisky, Green and Levine) adherence scale. The results of the study involving 220 respondents showed that the majority of respondents were women, with an age range of 45-59 years (middle age) and with a low level of education (elementary school graduates). The duration of illnesses was >1-5 years with the majority (50.9%) of patients having a low level of medication adherence. There is no association between patient’s characteristics and adherence. Adherence to taking medication for hypertensive patients in rural areas is low. Pharmacists need to give full attention and think of appropriate interventions to increase patient adherence with medication in rural areas.

Cite this article:
Husnawati, Elin Yulinah Sukandar, Kusnandar Anggadiredja. Medication Adherence and Characteristics of Hypertensive Patients: A Study in Rural Areas. Research Journal of Pharmacy and Technology. 2022; 15(1):370-4. doi: 10.52711/0974-360X.2022.00060

Husnawati, Elin Yulinah Sukandar, Kusnandar Anggadiredja. Medication Adherence and Characteristics of Hypertensive Patients: A Study in Rural Areas. Research Journal of Pharmacy and Technology. 2022; 15(1):370-4. doi: 10.52711/0974-360X.2022.00060   Available on:

1.    Liang HB. The classification of common antihypertensive drugs and clinical practice. Clinical Focus. 2011; 26(24): 2186–2188.
2.    Al-Ramahi R. Adherence to medications and associated factors: A cross-sectional study among Palestinian hypertensive patients. Journal of Epidemiology and Global Health. 2015; 5(2): 125–132.
3.    Kamran A, et al. Determinants of patient’s adherence to hypertension medications: application of health belief model among rural patients. Annals of Medical and Health Sciences Research. 2014; 4(6): 922-927.
4.    Venkatachalam J, et al. Determinants of patient's adherence to hypertension medications in a rural population of Kancheepuram District in Tamil Nadu, South India. Indian Journal of Community Medicine: Official Publication of Indian Association of Preventive and Social Medicine. 2015; 40(1): 33.
5.    Ma C. A cross-sectional survey of medication adherence and associated factors for rural patients with hypertension. Applied Nursing Research. 2016; 31: 94-99.
6.    Nguyen C, et al. Adherence to hypertension medication: Quantitative and qualitative investigations in a rural Northern Vietnamese community. PloS one. 2017; 12(2): e0171203.
7.    Rahmawati R, Bajorek B. Factors affecting self-reported medication adherence and hypertension knowledge: A cross-sectional study in rural villages, Yogyakarta Province, Indonesia. Chronic Illness. 2018; 14(3): 212-227.
8.    Chukumnird S, et al. Factors influencing adherence to preventive behaviors among Thais with hypertension: A literature review. Walailak Journal of Science and Technology (WJST). 2019; 16(8): 509-521.
9.    Chow CK, et al. Prevalence, awareness, treatment, and control of hypertension in ruraland urban communities in high-, middle-, and low-income countries. Journal of the American Medical Association. 2013; 310(9): 959–968.
10.    Archana S, Ram M. A prospective study on assessment of medication adherence of patients towards antihypersentive medications. Research Journal of Pharmacy and Technology. 2017; 10(11): 3779-3782.
11.    Indonesian Ministry of Health (Kementerian Kesehatan Republik Indonesia). Ministry of health strategic plan 2015-2019. Indonesian Ministry of Health, Jakarta. 2015.
12.    Banning MA. Review of interventions used to improve adherence to medication in older people. International Journal of Nursing Studies. 2009; 46: 1505-1515.
13.    National Centre for Cardiovascular Disease. Report on cardiovascular diseases in China, 2008–09. Encyclopedia of China Publishing House, Beijing. 2010.
14.    Sibomana JP, et al. Patient, clinician and logistic barriers to blood pressure control among adult hypertensives in rural district hospitals in Rwanda: a cross-sectional study. BMC Cardiovascular Disorders. 2019; 19(1): 1-8.
15.    Patidar K, Kalal S. A Study to assess the effectiveness of video assisted teaching on knowledge regarding prevention of stroke among hypertensive patients in selected hospitals of Mehsana. International Journal of Advances in Nursing Management. 2019; 7(2): 89-90.
16.    Athiyah U, et al. The influence of participation of the social security agency (bpjs) health on therapeutic success in hypertension patients at community health centers. Research Journal of Pharmacy and Technology. 2019; 12(1): 93-98.
17.    Pristianty L, et al. Effects of behavior factor on patients’ adherence to antihypertensive medicine taking at Pucang Sewu local government clinic Surabaya. Research Journal of Pharmacy and Technology. 2020; 13(4): 1623-1626.
18.    Rasajati QP, et al. Factors related to medication adherence in patients with hypertension in the work area of Puskesmas Kedungmundu kota Semarang. Unnes Journal of Public Health. 2015; 4(3): 16-23.
19.    Wahyudi CT, et al. The influence of demographic, psychosocial, and duration of primary hypertension on adherence to take antihypertensive drugs. JKFT Journal. 2018; 2(2): 14-28.
20.    Magnabosco P, et al. Comparative analysis of non-adherence to medication treatment for systemic arterial hypertension in urban and rural populations. Revista Latino-Americana de Enfermagem. 2015; 23(1): 20-27.
21.    Suoth M, et al. Relationship of lifestyle with the event of hypertension in Puskesmas Kolongan Kalawat North Minahasa District. Nursing ejournal (e-Kp.). 2014; 2(1): 1-10.
22.    Pramana GA, et al. Factors that influence medication adherence in hypertensive patients participating in prolanis in Puskesmas Pringapus Semarang District. Indonesian Journal of Pharmacy and Natural Product. 2019; 2(1): 52-58.
23.    Girija M, Kokilavani N. Effectiveness of structured teaching programme on knowledge, attitude and practice among patients with hypertension. Asian Journal of Nursing Education and Research. 2014; 4(1): 136-139.
24.    Kaur M. A Quasi experimental study on effectiveness of structured teaching programme on knowledge regarding complementary modalities of hypertension among hypertensive patients in selected rural areas of District Jalandhar, Punjab 2012. International Journal of Advances in Nursing Management. 2016; 4(2): 141-147.
25.    Alsolami F, et al. Factors affecting antihypertensive treatment adherence: a Saudi Arabian perspective. Clinical Medicine and Diagnostics. 2012; 2(4): 27-32
26.    Nielsen JO, et al. Non-adherence to anti-hypertensive medication in low- and middle-income countries: A systematic review and meta-analysis of 92443 subjects. J Hum Hypertens. 2017; 31: 14–21.
27.    Sulochana C, Rani SJ. Quasi experimental study to assess the relationship between lifestyle and blood pressure among prehypertensive employees in a workplace hypertension prevention program at Kanyakumari District, Tamil Nadu. Asian Journal of Nursing Education and Research. 2019; 9(3): 323-326.
28.    Sumathy P, et al. A prospective study on comparative efficacy between two combinational therapies for hypertension. Research Journal of Pharmacy and Technology. 2016; 9(11): 2005-2008.
29.    Yeswanthi S, Jayakumari S. A prospective study on combinational drug efficacy in hypertensive patients. Research Journal of Pharmacy and Technology. 2018; 11(2): 509-512.
30.    Bowry AD, et al. A systematic review of adherence to cardiovascular medications in resource-limited settings. Journal of General Internal Medicine. 2011; 26(12): 1479-1491.
31.    Mathew AC, et al. Assessment of medication adherence patterns and various causes of non-adherence in long term therapies in a tertiary care hospital. Research Journal of Pharmacy and Technology. 2020; 13(5): 2420-2426.
32.    Balasubramanian A, et al. Adherence to treatment among hypertensives of rural Kerala, India. Journal of Family Medicine and Primary Care. 2018; 7(1): 64.
33.    Kakumani KV, Waingankar P. Assessment of compliance to treatment of diabetes and hypertension amongst previously diagnosed patients from rural community of Raigad District of Maharashtra. J Assoc Physicians India. 2016; 64(12): 36-40.
34.    Fatima J, et al. Patient medication adherence and the health outcome. Asian Journal of Pharmaceutical Research. 2018; 8(2): 78-82.

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