Author(s): Srinivasa Rao Narala, K. Saraswathi

Email(s): srinunarala@gmail.com

DOI: 10.52711/0974-360X.2022.00049   

Address: Srinivasa Rao Narala1*, K. Saraswathi2
1Department of Chemistry, R.V.R. & J.C. College of Engineering, Guntur, A.P., India.
2Department of Chemistry, S.V. University, Tirupathi, A.P., India.
*Corresponding Author

Published In:   Volume - 15,      Issue - 1,     Year - 2022


ABSTRACT:
A simple, rapid and sensitive reverse phase high performance liquid chromatographic method has been developed for the determination of Mesalamine in bulk drug and pharmaceutical dosage forms. It was carried out using a mobile phase of methanol and 0.025 M potassium dihydrogen phosphate buffer (65:35 v/v) on a kromosil C18 column (250 X 4.6 mm, 5µm) in an isocratic mode at a flow rate of 1.0 ml/min. with detection at 250 nm using a UV detector. The linearity was obtained in the concentration range of 20 –100 µg/ml. The developed method was found to be accurate for the determination of Mesalamine in tablet dosage forms.


Cite this article:
Srinivasa Rao Narala, K. Saraswathi. High Performance Liquid Chromatographic Method for the Determination of Mesalamine in Bulk Drug and Pharmaceutical Dosage Forms. Research Journal of Pharmacy and Technology. 2022; 15(1):301-4. doi: 10.52711/0974-360X.2022.00049

Cite(Electronic):
Srinivasa Rao Narala, K. Saraswathi. High Performance Liquid Chromatographic Method for the Determination of Mesalamine in Bulk Drug and Pharmaceutical Dosage Forms. Research Journal of Pharmacy and Technology. 2022; 15(1):301-4. doi: 10.52711/0974-360X.2022.00049   Available on: https://rjptonline.org/AbstractView.aspx?PID=2022-15-1-49


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