Author(s): Amel S. Mahdi, Barakat A. F. Kamel, Athraa S. Ahmed, Kafi M. Dawood

Email(s): baraka1983@uomustansiriyah.edu.iq

DOI: 10.52711/0974-360X.2021.00868   

Address: Amel S. Mahdi, Barakat A. F. Kamel*, Athraa S. Ahmed, Kafi M. Dawood
Department of Chemistry, College of Science, Al-Mustansiriyah University, Iraq.
*Corresponding Author

Published In:   Volume - 14,      Issue - 9,     Year - 2021


ABSTRACT:
In this work the photo degradation of glibinclamide is studied by UV light and different concentrations using solvents (water and ethanol) and different times. The reaction kinetic is studied and found that the photo degradation reaction of glibinclamide is (first-order) reaction and the thermodynamic properties (?Ho, ?So and ?Go) for glibinclamide were calculated and it was found to be (endothermic and spontaneous reaction).


Cite this article:
Amel S. Mahdi, Barakat A. F. Kamel, Athraa S. Ahmed, Kafi M. Dawood. Kinetic, Thermodynamic Studies for Photo Degradation of Glibinclamide Drug. Research Journal of Pharmacy and Technology. 2021; 14(9):4987-0. doi: 10.52711/0974-360X.2021.00868

Cite(Electronic):
Amel S. Mahdi, Barakat A. F. Kamel, Athraa S. Ahmed, Kafi M. Dawood. Kinetic, Thermodynamic Studies for Photo Degradation of Glibinclamide Drug. Research Journal of Pharmacy and Technology. 2021; 14(9):4987-0. doi: 10.52711/0974-360X.2021.00868   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-9-82


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2.    Erejuwa OO., Sulaiman SA., Wahab MS., Sirajudeen KNS., Salzihan Md., Salleh Md and Gurtu S., Antioxidant Protective Effect of Glibenclamide and Metformin in Combination with Honey in Pancreas of Streptozotocin- Induced Diabetic Rats., Int. J. Mol. Sci., 2010; 11: 2056-2066.
3.    Gensheng Z., Xiuhui L., Shufang Z., Huiqing X., Chuli P. and Wei C., A Protective Role of Glibenclamide in Inflammation- Associated Injury., Mediators of Inflammation., 2017; 2017: 11.
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