Author(s): Nadar Sowmya, Chouhan Raghavendra Singh, Kosha Patel, Harshil Patel, Tanvi Dodiya, Muthu Kumaradoss Mohan Maruga Raja

Email(s): sowmyanadar07@gmail.com , raghven.chouhan25@gmail.com , koshapatel99@gmail.com , pharshil208@gmail.com , tanvi.dodiya@paruluniversity.ac.in , mohan.raja19169@paruluniversity.ac.in

DOI: 10.52711/0974-360X.2021.00808   

Address: Nadar Sowmya, Chouhan Raghavendra Singh, Kosha Patel, Harshil Patel, Tanvi Dodiya, Muthu Kumaradoss Mohan Maruga Raja*
Department of Pharmacognosy and Phytochemistry, Parul Institute of Pharmacy and Research, Parul University, Vadodara, Gujarat, India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 9,     Year - 2021


ABSTRACT:
According to the literature survey most of the studies done on Adarak (Zingiber officinale rhizome) were performed on alcoholic extracts or isolated entities of ginger but no profound work has been done on the traditionally prepared or commonly consumed way of ginger. So, in this current study, fresh ginger rhizomes were traditionally pounded to make Adarak juice. The different concentration (0.05%, 0.5%, 1%, 2.5%, 5%, 10%) were taken as sample to perform onion root tip inhibition assay and brine shrimp lethality bioassay. It showed antimitotic inhibition in the range of 0.05-10% concentration with an IC50 value of 0.37 % on number of rootlets was 0.08 % on length of rootlets. The traditionally prepared Adarak juice showed cytotoxicity in the range of 0.05-2.5% concentration with LC50 value of 1.59%. The traditionally prepared Adarak juice possesses cytotoxic and antimitotic activity.


Cite this article:
Nadar Sowmya, Chouhan Raghavendra Singh, Kosha Patel, Harshil Patel, Tanvi Dodiya, Muthu Kumaradoss Mohan Maruga Raja. In-vitro and in vivo studies of traditionally prepared Zingiber officinale juice for Antimitotic and Lethality activity. Research Journal of Pharmacy and Technology. 2021; 14(9):4652-6. doi: 10.52711/0974-360X.2021.00808

Cite(Electronic):
Nadar Sowmya, Chouhan Raghavendra Singh, Kosha Patel, Harshil Patel, Tanvi Dodiya, Muthu Kumaradoss Mohan Maruga Raja. In-vitro and in vivo studies of traditionally prepared Zingiber officinale juice for Antimitotic and Lethality activity. Research Journal of Pharmacy and Technology. 2021; 14(9):4652-6. doi: 10.52711/0974-360X.2021.00808   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-9-22


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