Author(s): Mohamed J. Saadh, Saed M. Aldalaen, Hala M. Sbaih

Email(s): msaadeh@meu.edu.com

DOI: 10.52711/0974-360X.2021.00780   

Address: Mohamed J. Saadh1*, Saed M. Aldalaen2, Hala M. Sbaih3
1Faculty of Pharmacy, Middle East University, Amman, Jordan.
2Department of Pharmacology, Faculty of Pharmacy, Mutah University, Jordan.
3Faculty of Pharmacy, Isra University, Amman, Jordan.
*Corresponding Author

Published In:   Volume - 14,      Issue - 8,     Year - 2021


ABSTRACT:
There are several circulated hormones that control intravascular blood volume which are secreted from cardiac tissue, such as atrial natriuretic peptide (ANP) and brain (B-type) natriuretic peptide (BNP). These peptides will be elevated in case of heart failure (HF), and because of their diuretic, natriuretic, vasodilating effects as well as suppressing renin production they will work as compensated for HF. The natriuretic peptides system has critical effect against renin – angiotensin – aldosterone system (RAAS). A suggested therapeutic approach was discussed in HF treatment via performing human recombinant ANP and BNP, but it’s requiring more clinical trials to evaluate the quality of this approach compared to conventional treatment.


Cite this article:
Mohamed J. Saadh, Saed M. Aldalaen, Hala M. Sbaih. Inhibitors of Neutral Peptidase. Research Journal of Pharmacy and Technology. 2021; 14(8):4491-4. doi: 10.52711/0974-360X.2021.00780

Cite(Electronic):
Mohamed J. Saadh, Saed M. Aldalaen, Hala M. Sbaih. Inhibitors of Neutral Peptidase. Research Journal of Pharmacy and Technology. 2021; 14(8):4491-4. doi: 10.52711/0974-360X.2021.00780   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-86


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