Author(s): Made Krisna Adi Jaya, Dewa Ayu Swastini, Baiq Leny Nopitasari, Putu Rika Veryanti

Email(s): krisnaadijaya@unud.ac.id

DOI: 10.52711/0974-360X.2021.00700   

Address: Made Krisna Adi Jaya1*, Dewa Ayu Swastini1, Baiq Leny Nopitasari2, Putu Rika Veryanti3
1Department of Pharmacy, Faculty of Math and Science, Udayana University, Bali-Indonesia.
2Department Pharmacology and Clinical Pharmacy, Faculty of Health Sciences, University of Muhammadiyah Mataram-Indonesia.
3Department of Pharmacy, Faculty of Pharmacy, Institut Sains dan Teknologi Nasional, Jakarta-Indonesia.
*Corresponding Author

Published In:   Volume - 14,      Issue - 8,     Year - 2021


ABSTRACT:
Background: Diabetic Peripheral Neuropathy (DPN) is a microvascular complication that commonly occurs in people with diabetes mellitus. Geriatrics with type 2 diabetes mellitus is one of the populations most vulnerable to this complication. An epidemiological study states that geriatrics has a 32% greater risk of developing this complication compared to other age groups. There have not been many studies conducted to evaluate the risk factors that influence this DPN complication, so it needs to be done an individual evaluation for the elderly population. Objective: This study aims to explore the risk factors that influence the incidence of DPN in elderly patients with type 2 diabetes mellitus. Methods: A case-control study design was carried out on 70 geriatrics with type 2 diabetes mellitus. The outcome determined was the incidence of DPN to track the cause of DPN exposure retrospectively. Influential risk factors are determined by the Odds Ratio (OR) with a 95% confidence interval (CI). All statistical analyzes were two-tailed, and p-values <0.05 were considered as statistically significant. Results: Seven factors influence the incidence of DPN in the elderly consisting of smoking history (OR=13.1), uncontrolled lipid profile (OR=5.1), non-neuroprotector users (OR=5.6), uncontrolled blood glucose (OR=42.7), history of heart disease (OR=9.0), uncontrolled blood pressure (OR=4.3), and BMI above normal (OR=5.1). Conclusion: Strong recommendation for medical personnel to focus attention on seven significant risk factors affected complications of DPN to reduce its progression or prevent upcoming complications.


Cite this article:
Made Krisna Adi Jaya, Dewa Ayu Swastini, Baiq Leny Nopitasari, Putu Rika Veryanti. A Case-Control Study on Risk Factors affected Peripherals Neuropathic complication in Elderly with Type 2 Diabetes Mellitus. Research Journal of Pharmacy and Technology. 2021; 14(8):4040-6. doi: 10.52711/0974-360X.2021.00700

Cite(Electronic):
Made Krisna Adi Jaya, Dewa Ayu Swastini, Baiq Leny Nopitasari, Putu Rika Veryanti. A Case-Control Study on Risk Factors affected Peripherals Neuropathic complication in Elderly with Type 2 Diabetes Mellitus. Research Journal of Pharmacy and Technology. 2021; 14(8):4040-6. doi: 10.52711/0974-360X.2021.00700   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-6


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