Author(s): Avinash Sharma, Rupak Nagraik, Somesh Sharma, P. K. Chauhan

Email(s): avinash.subms@gmail.com

DOI: 10.52711/0974-360X.2021.00752   

Address: Avinash Sharma, Rupak Nagraik, Somesh Sharma, P. K. Chauhan*
Faculty of Applied Sciences and Biotechnology, Shoolini University, Solan, 173229, (H.P) India.
*Corresponding Author

Published In:   Volume - 14,      Issue - 8,     Year - 2021


ABSTRACT:
Plant based compounds are used as an alternate to chemically synthesized compounds in pharmaceutical industries. The main aim of the study was to evaluate the phytochemical, antioxidant and antimicrobial activities of leaf extract of two medicinal plants i.e. Murraya koiengii and Ficus palmata collected from north-western Himalayan region. The phytochemical screening of these plant extract showed the presence of alkaloids, phenols, tannins, flavonoids and the absence of terpenoids and saponins. The qualitative data analysis confirmed the highest level of phytochemicals in Murraya koiengii plant extract as compared to Ficus palmata. The antioxidant results show the dose dependent manner. The minimum inhibitory concentration (MIC) value of the extracts was found at concentration of 1.5625 mg/ml for Murraya koiengii and 3.125 mg/ml for Ficus palmata. The present study supports the use plant extracts as an alternative medicine in the ailment of many diseases.


Cite this article:
Avinash Sharma, Rupak Nagraik, Somesh Sharma, P. K. Chauhan. In-vitro Antioxidant and Antimicrobial activities of Murraya koiengii and Ficus palmata leaf extracts from North-western Himalayan Region. Research Journal of Pharmacy and Technology. 2021; 14(8):4332-6. doi: 10.52711/0974-360X.2021.00752

Cite(Electronic):
Avinash Sharma, Rupak Nagraik, Somesh Sharma, P. K. Chauhan. In-vitro Antioxidant and Antimicrobial activities of Murraya koiengii and Ficus palmata leaf extracts from North-western Himalayan Region. Research Journal of Pharmacy and Technology. 2021; 14(8):4332-6. doi: 10.52711/0974-360X.2021.00752   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-58


REFERENCES:
1.    Pratibha, C., Madhumati, B., Akarsh, P. (2013) Therapeutic properties and significance of different parts of Ashwagandha–a medicinal plant. International Journal of Pure and Applied Bioscience, 1: 94-101.
2.    Yadav, RN., Agarwala, M. (2011) Phytochemical analysis of some medicinal plants. Journal of Phytology. 14.
3.    Rupasinghe HV, Sekhon-Loodu S, Mantso T, Panayiotidis MI (2016) Phytochemicals in regulating fatty acid β-oxidation: Potential underlying mechanisms and their involvement in obesity and weight loss. Pharmacol Therap. 165: 153-163.
4.    Mothana RA, Abdo SA, Hasson S, Althawab F, Alaghbari SA, Lindequist U. (2010) Antimicrobial, antioxidant and cytotoxic activities and phytochemical screening of some yemeni medicinal plants. Evid Based Compl Alt Med. 7(3): 323-3230.
5.    Vats M, Singh H, Sardana S. (2011) Phytochemical screening and antimicrobial activity of roots of Murraya koenigii (Linn.) Spreng. (Rutaceae). Braz J Microbiol. 42(4): 1569-1573.
6.    Narendhirakannan RT, Subramanian S, Kandaswamy M. (2005) Mineral content of some medicinal plants used in the treatment of diabetic mellitus. Biol Trace Elem Res. 103: 109-115.
7.    Vinuthan MK, Girish Kumar V, Ravindra JP, Narayana K. (2004) Effect of extracts of Murraya koenigii leaves on the levels of blood glucose and plasma insulin in alloxan-induced diabetic rats. Indian J Physiol Pharmacol. 48(3): 348-352.
8.    Anonymous, “The Wealth of India”, (2000) National Institute of Science Communications and Information Resources, Council of Scientific & Industrial Research, New Delhi, First Supplement Series, Vol. 4, 168-169.
9.    Bohlooli S, Mohebipoor A, Mohammadi S. (2007) Comparative study of fig tree efficacy in the treatment of common warts (Verruca vulgaris) vs. cryotherapy. Int J Dermatol. 46: 524-526.
10.    Fatemi A, Rasouli A, Asadi F. (2007) Effect of Fig (Ficus carica) Leaf Extract on the Secretion and Content of Cholesterol in Hepg2 Cell. Am J Anim Vet Sci. 2(4): 104-107.
11.    Gilani AH, Mehmoodm H, Janbaz KH, Khan A, Saeed SA. (2008) Ethnopharmacological studies on antispasmodic and antiplatelet activities of F. carica. J Ethnopharmacol. 119(1): 1-5.
12.    Brain KR, Turner TD. (1975) The practical evaluation of phytopharmaceuticals. Bristol: Wright Science Technica.
13.    Trease GE, Evans WC. Pharmacognosy. (1989) 11th Edn., Macmillan Publishers.; London, UK.
14.    Harborne JB. (1973) Phytochemical Methods. Chapman and Hall Ltd., London, UK.1973; pp: 49-188.
15.    Sofowora A. (1993) Medicinal Plants and Traditional Medicine in Africa. 2nd Edn., Spectrum Books Ltd., Ibadan, Nigeria. ISBN-13: 9789782462190, Pages: 289.
16.    Silva LG, Lee IS, Kinghorn DA. (1998) Special problem with the extraction of plants. In: Cannell RJP, ed. Natural Products Isolation. New Jersey, USA: Humana Press Inc: 343- 364.
17.    Rashid A, Quereshi MZ, Raza SA, William J, Arshad M. (2010) Quantitative determination of antioxidant potential of Artemisia persica. Department of chemistry, GCU, Lahore, Pakistan. 19: 23-30.
18.    Obdoni BO, Ochuko PO. (2001) Phytochemical studies and comparative efficacy of the crude extracts of some Homostatic plants in Edo and Delta States of Nigeria. Global J Pure Appl Sci. 8(2): 203-208.
19.    Shon DH, Kim YC, Oh SH. (2003) Hepatoprotective and free radical scavenging effects of Nelumbo nucifera. Phytomed. 10: 165-169.
20.    Benzie IF, Strain JJ. (1999) Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol. 299: 15-27.
21.    Usman H, Haruna AK, Akpulu IN, Ilyas M, Ahmadu AA, Musa YM. (2005) Phytochemical and antimicrobial screenings of the leaf extracts of Celtis integrifolia Lam. J Trop Biosci. 5(2): 72-76.
22.    Pavithra PS, Janani VS, Charamathi KH, Indumathy R, Potala S, Verma RS. (2010) Antibacterial activity of plants used in Indian herbal medicine. Int J Green Pharm. 4(1): 22-8.
23.    Cowan MM.(1999) Plant products as antimicrobial agents. Clin Microbiol Rev. 12(4): 564-82.
24.    Olajuyigbe OO, Babalola AE, Afolayani AJ. (2011) Antibacterial and phytochemical screening of crude ethanolic extracts of Waltheria indica Linn. Afr J Microbiol Res. 5(22): 3760- 4.
25.    Kostova I, Dinchev D. (2005) Saponins in Tribulus terrestris – chemistry and bioactivity. Phytochem Rev. 4(2): 111- 37.
26.    Deshi JJ, Barminas JT, Onwuka J, Dass PM, Maitera O, Muazu I. (2016) Antimicrobial efficacy of biosynthesized silver nanoparticles from different solvent extracts of Waltheria americana root. J Anal Sci Technol. 7(1): 23.

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