Author(s): Vinod K Mathew, Kishore Gnana Sam, Beulah Milton, Amit Kumar Das

Email(s): mathewvino@gmail.com

DOI: 10.52711/0974-360X.2021.00740   

Address: Vinod K Mathew1*, Kishore Gnana Sam2, Beulah Milton3, Amit Kumar Das4
1Dept. of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore – 35.
2Associate Professor, Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, UAE. 3Professor, Department of Pharmacy Practice, Krupanidhi College of Pharmacy, Bangalore – 35.
4Principal, Krupanidhi College of Pharmacy, Bangalore – 35.
*Corresponding Author

Published In:   Volume - 14,      Issue - 8,     Year - 2021


ABSTRACT:
Background: Schizophrenia is a burdensome illness which virtually affects all aspects of the patient’s life. There is a lack of national level data from India on prescription pattern of Antipsychotics Polypharmacy and other drugs combination in the treatment of Schizophrenia. Aim and Objectives: To evaluate Prescription pattern of Antipsychotic Polypharmacy in schizophrenia. Methodology: The medication records of patients admitted from August 2006 to May 2007 were reviewed to evaluate the prescription pattern of antipsychotics poly pharmacy, Demography of the patients like age, sex, were also evaluated. Results: The medical records of 139 schizophrenic patients were reviewed, out of 139 patients 30.93% (n = 43) patients received combination therapy. In combination therapy 28.77% (n=40) were prescribed two antipsychotics and 0.007% (n= 3) were prescribed three antipsychotic drugs. The average age was 34.4±11.9 years. F 20.0 Paranoid schizophrenia received maximum prescriptions for combination therapy 18.71% (n=26). Comparison of adjunct medication showed Anxiolytics and Anticholinergics 17.26% (n=25) received maximum prescriptions for combination therapy A total of 20.86% (n=29) received combination of Second Generation Antipsychotics SGA + First Generation Antipsychotics FGA, maximum patients 18 was in the combination of Haloperidol + Resperidone. Conclusion: The present study revealed an increasing trend of polypharmacy among schizophrenia patients admitted in a tertiary care hospital. The present study demonstrate the rate of antipsychotic polypharmacy is relatively low in India


Cite this article:
Vinod K Mathew, Kishore Gnana Sam, Beulah Milton, Amit Kumar Das. Prescription Pattern of Antipsychotics Polypharmacy in patients with Schizophrenia in an Indian Hospital. Research Journal of Pharmacy and Technology. 2021; 14(8):4265-9. doi: 10.52711/0974-360X.2021.00740

Cite(Electronic):
Vinod K Mathew, Kishore Gnana Sam, Beulah Milton, Amit Kumar Das. Prescription Pattern of Antipsychotics Polypharmacy in patients with Schizophrenia in an Indian Hospital. Research Journal of Pharmacy and Technology. 2021; 14(8):4265-9. doi: 10.52711/0974-360X.2021.00740   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-46


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