Author(s): VA Kurkin, EA Kupriyanova

Email(s): kurkinvladimir@yandex.ru

DOI: 10.52711/0974-360X.2021.00726   

Address: VA Kurkin*, EA Kupriyanova
Department of Pharmacognosy, Botany and Phytotherapy, Samara State Medical University, Ulitsa Chapaevskaya 89, Samara, 443099, Russian Federation.
*Corresponding Author

Published In:   Volume - 14,      Issue - 8,     Year - 2021


ABSTRACT:
From the leaves of the black poplar (Populus nigra L., Salicaceae family) there were for the first time isolated rutin (quercetin-3-O-rutinoside), calendoflavobioside (quercetin-3-O-neohesperidoside) (flavonoids) and ferulic acid (phenylpropanoid) by using of liquid column chromatography. The chemical structures of the isolated compounds there were elucidated by means of 1H-NMR-, 13C-NMR-, UV-spectroscopy, mass spectrometry and results of chemical transformations. The isolated flavonoids are the dominant phenolic components of the raw material of the investigated plant. It was determined, that the isolated flavonoids cause the spectral characteristics of the UV spectra of the water-ethanolic extract from the Populus nigra leaves. It was substantiated the expediency of the estimation of the total flavonoids in the leaves of Populus nigra calculated on rutin. As results there was development the method of the quantitative determination of the total flavonoids in the leaves of Populus nigra by the using of the differential spectrophotometry at an analytical wavelength of 414 nm. It was determined that the content of the total flavonoids in the raw materials of the studied plant varies from 2.04±0.09% to 2.99±0.11%. The relative degree of the determination of the total flavonoids in the leaves of black poplar in developed method with confidence probability 0.95 is no more than ± 6.26%.


Cite this article:
VA Kurkin, EA Kupriyanova. The Phytochemical Study of the Populus nigra L. Leaves. Research Journal of Pharmacy and Technology. 2021; 14(8):4192-6. doi: 10.52711/0974-360X.2021.00726

Cite(Electronic):
VA Kurkin, EA Kupriyanova. The Phytochemical Study of the Populus nigra L. Leaves. Research Journal of Pharmacy and Technology. 2021; 14(8):4192-6. doi: 10.52711/0974-360X.2021.00726   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-8-32


REFERENCES:
1.    Braslavskii VB. Willow, Poplar, and Propolis in Medicine and Pharmacy: Monograph [in Russian]; Samara: Oxford Publ.; 2012; pp. 116.
2.    Plant Resources of the USSR: Flowering Plants, Their Chemical Composition and Use: Families Paeoniaceae – Thymelaeaceae; Leningrad: Nauka; 1986; pp. 336.
3.    The State Pharmacopoeia of the Russian Federation [in Russian], XIV edition, Vol. 4, Moscow; 2018; pp. 1832 [Electronic resource] / URL: http://resource.rucml.ru/feml/pharmacopia/14_4/HTML/index.html - 26.04.2020.
4.    Turetskova VF, Lobanova IYu, Rassypnova SS, Talykova NM. Populus tremula as a promising source of anti-ulcer and anti-inflammatory drugs [in Russian]; Bulletin of Siberian Medicine; 2011; 5: 106-111.
5.    Kurkin VA. Pharmacognosy: A Textbook for Students of Pharmaceutical Universities; Ed. 4th, rev. and add. [in Russian]; Samara:  Oxford Publ.; 2019; pp. 1278.
6.    Mabry TJ, Markham KR, Thomas MB. The Systematic Identification of Flavonoids; Berlin-Heidelberg-New York: Springer Verlag, 1970; pp. 354.
7.    Akkola EK, Süntara I, Keleşb H, Sezika E, Gürlerc G. Bioassay-guided isolation and characterization of wound healer compounds from Morus nigra L. (Moraceae); Rec. Nat. Prod.; 2015; 9(4): 484–495.
8.    Komissarenko NF, Chernobai VT, Derkach AI. Flavonoids of inflorescences of Calendula officinalis; Chemistry of Natural Compounds; 1988; 24(6): 675-680.

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