Author(s): Candra Irawan, Hanafi, Henny Rochaeny, Lilis Sulistiawaty, Andita Utami, Imalia Dwi Putri

Email(s): andita.utami@gmail.com

DOI: 10.52711/0974-360X.2021.00610   

Address: Candra Irawan1, Hanafi2, Henny Rochaeny1, Lilis Sulistiawaty1, Andita Utami1*, Imalia Dwi Putri2
1Department of Chemical Analysis, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia.
2Department of Food Industry Quality Insurance, Politeknik AKA Bogor, Jalan Pangeran Sogiri, Tanah Baru, Bogor 16154, Indonesia.
*Corresponding Author

Published In:   Volume - 14,      Issue - 7,     Year - 2021


ABSTRACT:
Mangifera quadrifida Jack (Isem Kembang) is a rare fruit native to Lampung, Southern Sumatera, Indonesia. Phytochemical composition and antioxidant activity in Mangifera quadrifida Jack baby fruits are still unknown. This study aims to analyze the phytochemical compounds and antioxidant activity contained in Mangifera quadrifida Jack baby fruit extracts. In this study, the baby fruit of Mangifera quadrifida Jack was extracted using n-hexane, ethyl acetate, and methanol as the solvent in a separate experiment. Phytochemical tests were carried out for all extracts, followed by analysis of volatile compounds using GC-MS (Gas Chromatography – Mass Spectrometry). Then the antioxidant activity test was carried out on all three extracts to assess the inhibitory activity against DPPH (2,2-diphenyl-1-picrylhydrazyl) free radicals. Phytochemical test results of Mangifera quadrifida Jack extracts revealed the presence of various bioactive compounds. GC-MS analysis providesl information about volatile compound content for each extract, which involves alkanes, alkenes, esters, carboxylates, phenolic compounds, aromatics, and aldehydes. Antioxidant activity investigation of the extracts obtained from n-hexane, ethyl acetate and methanol showed the IC50 values of 430.63ppm, 24.52ppm, and 23.67 ppm, respectively. This shows that the baby fruit of Mangifera quadrifida Jack can be used as an alternative source of natural antioxidants.


Cite this article:
Candra Irawan, Hanafi, Henny Rochaeny, Lilis Sulistiawaty, Andita Utami, Imalia Dwi Putri. Phytochemical Screening, Volatile Compound Analysis, and Antioxidant Activity of Mangifera quadrifida Jack (Isem Kembang) Baby Fruit collected from Lampung, Indonesia. Research Journal of Pharmacy and Technology. 2021; 14(7):3523-7. doi: 10.52711/0974-360X.2021.00610

Cite(Electronic):
Candra Irawan, Hanafi, Henny Rochaeny, Lilis Sulistiawaty, Andita Utami, Imalia Dwi Putri. Phytochemical Screening, Volatile Compound Analysis, and Antioxidant Activity of Mangifera quadrifida Jack (Isem Kembang) Baby Fruit collected from Lampung, Indonesia. Research Journal of Pharmacy and Technology. 2021; 14(7):3523-7. doi: 10.52711/0974-360X.2021.00610   Available on: https://rjptonline.org/AbstractView.aspx?PID=2021-14-7-7


REFERENCES:
1.    Hermanto C, Indriani NLP, Hadiati I. Diversity of Archipelago Tropical Fruit: Agricultural Research and Development Agency. Jakarta: IAARD Press. 2013.
2.    Robinson T. Organic Content of Higher Plant. Bandung: ITB Press. 1995; 4th Edition.
3.    Harbone JB. Phytochemical Methods: Determination of Modern Ways to Analyze Plants. Bandung: ITB Press. 1996.
4.    Chakraborty P, Kumar S, Dutta D, Gupta V. Role of Antioxidants in Common Health Diseases. Research J. Pharm. and Tech.2 (2): April.-June. 2009.Page 238-244.
5.    Menon R. Antioxidants and their Therapeutic Potential - A Review. Research J. Pharm. and Tech. 6(12): 2013; Page 1426-1429.
6.    Vaishali M. Antioxidants in Health and Diseases. Research J. Pharm. and Tech. 7(4): April, 2014; Page 489-493.
7.    Pietta PG. Reviews: Flavonoid as Antioxidant. Journal National Product. 1999; 63:1035-1042.
8.    Kuncahyo I, Sunardi. Antioxidant Activity Test for Carambola Extract (Averrhoa bilimbi, L.) against 1,1-Diphenyl-2-Picrylhidrazyl (DPPH). National Seminar on Technology. Yogyakarta: 24 Nov 2007.
9.    Kayani SA, Masood A, Achakzai AKK, Anbreen S. Distribution of Secondary Metabolites in Plants of Quetta-Balochistan. Pakistan J. Botany. 2007; 39: 1173–1179.
10.    Khan AM, Qureshi RA, Ullah F, Gelani SA, Nohseen A. Phytochemical Analysis of Selected Medicinal Plants of Margalla Hills and Surroundings. J Med Plant Res. 2011; 5(25): 6017-6023.
11.    Ayoola GA, Coker H, Adesegun SA, Adepoju-Bello AA, Obaweya K, Ezennia EC, Atangbayila TO. Phytochemical Screening and Antioxidant Activities of Some Selected Medicinal Plants Used for Malaria Therapy in Southwestern Nigeria. Trop. J. Pharm. Res. 2008; 7: 1019–1024.
12.    Praveena A, Ramkumar G, Sanjayan KP. Phytochemical Screening of the Extract of the Root-Bark of Morinda tinctoria (Rubiaceae) for Secondary Metabolites. Research J. Pharm. and Tech. 5(1): Jan. 2012; Page 83-87.
13.    Molyneux P. The Use of The Stable Free Radical Diphenyl-picrylhydrazyl (DPPH) for Estimating Antioxidant Activity. Journal Science of Technology. 2004; 26(2): 211-219.
14.    Narasimhan R, Sathiyamoorthy M. Phytochemical Screening and Antioxidant Studies in the Pulp Extracts of Cucurbita maxima. Asian J. Pharm. Res. 6(1): January -March, 2016; Page 01-04. doi: 10.5958/2231-5691.2016.00001.0
15.    Gupta N, Agrawal RC, Shrivastava V,Roy A, Prasad P. In vitro Antioxidant Activity and Phytochemical Screening of Aegle marmelos Extracts. Research J. Pharmacognosy and Phytochemistry 2012; 4(2): 80-83.
16.    Tarange RG, Kharat JS, Jedage HD, Manjunath K . Phytochemical screening for Antioxidant and Antifungal activity of Lagenaria siceraria (Molina) Standl. leaf extract. Res. J. Pharmacognosy and Phytochem. 2019; 11(3): 155-159.
17.    Oskoueian E, Omar AR, Abdullah N, Ahmad S, Saad WZ, Ho YW. Bioactive Compounds and Biological Activities of Jatropha curcas, L.. Kernel Meal Extract Int. J. Mol. Sci. 2011; 12: 5955-5970.
18.    Miguel MG. Antioxidant and Anti- Inflammatory Activities of Essential Oils: A Short Review. Molecules. 2010; 15(12): 9252-9287.
19.    Astani A, Reichling J, Schnitzler P. Screening for Antiviral Activities of Isolated Compounds from Essential Oils. Evid Based Complement Alternat Med. 2011; 253-643.
20.    Marrufo T, Nazzaro F, Mancini E, Fratianni F, Coppola R, De Martino L, Agostinho AB, De Feo V. Chemical Composition and Biological Activity of the Essential Oil from Leaves of Moringa oleifera Lam. Cultivated in Mozambique. Molecules. 2013; 18: 10989-11000.
21.    Yoshida Y, Niki E. Antioxidant Effects of Phytosterol and Its Components. Journal of Nutritional Science and Vitaminology. 2003; 49: 277–280.
22.    Balamurugan R, Duraipandiyan V, Ignacimuthu S. Antidiabetic Activity of γ-sitosterol Isolated from Lippia nodiflora L. in Streptozotocin Induced Diabetic Rats. Eur J Pharmacol, 2011. 667: 410–8.
23.    Wagh SS, Jain SK, Patil AV, Vadnere GP. In vitro free radical scavenging and antioxidant activity of Cicer arietinum, L. (Fabaceae). Int. J. PharmTech. Res. 2012; 4(1): 343-350.
24.    Eitenmiller RR, Lee J. Vitamin E: Food Chemistry. Composition and Analysis. New York: Marcel Dekker. 2004.
25.    Roy A, Bhoumik D, Sahu RK, Dwivedi J. Phytochemical Screening and Antioxidant Activity of Sesbania grandiflora Leaves Extracts. Asian J. Res. Pharm. Sci. 4(1): Jan.-Mar. 2014; Page 16-21.
26.    Raj AJ, Dorairaj S. Phytochemical Screening and In-vitro Antioxidant Activity of Cissus quadrangua lris. Asian J. Research Chem. 3(4): Oct. - Dec. 2010; Page 876-878.
27.    Preeti, Jain A, Kumar G, Karthik L, Rao KVB. Phytochemical composition and antioxidant activity of Ficus elastica Roxb. (Moraceae) leaves. Research J. Pharm. and Tech. 8(3): Mar, 2015; Page 259-264.

Recomonded Articles:

Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal.... Read more >>>

RNI: CHHENG00387/33/1/2008-TC                     
DOI: 10.5958/0974-360X 

1.3
2021CiteScore
 
56th percentile
Powered by  Scopus


SCImago Journal & Country Rank

Journal Policies & Information


Recent Articles




Tags


Not Available